mivacurium and Obesity

Mivacurium is a short-acting non-deplolarizing neuromuscular blocking agent. Its use in an obese patient with myotonic dystrophy undergoing laparoscopic cholecystectomy is reported. Mivacurium was used as a bolus dose of 0.07 mg. kg-1, followed by a continuous infusion at the rate of 0.003 mg. kg-1. min-1. Muscle relaxation, monitored by a train of four count, was adequate throughout the surgery. Spontaneous recovery of the neuromuscular function was obtained fifteen minutes after the end of mivacurium infusion. Neostigmine was not given. Postoperative mechanical ventilation and respiratory complications were avoided.

Topics: Anesthesia; Cholecystectomy; Female; Humans; Isoquinolines; Laparoscopy; Middle Aged; Mivacurium; Myotonic Dystrophy; Neuromuscular Nondepolarizing Agents; Obesity; Respiratory Function Tests