mivacurium and Diabetic-Retinopathy

Maintaining intraocular pressure (IOP) is important in preventing ocular complications in patients undergoing ophthalmic surgery for general anesthesia. The effects of non-depolarizing neuromuscular blockers on IOP remain unclear. The present study compared the effects of cisatracurium, rocuronium, and mivacurium on IOP during induction of general anesthesia in vitreous retinal surgery.. In this prospective randomized double-blinded study, 133 patients undergoing vitreous retinal surgery were randomized into one of the three groups: Group cisatracurium (n=45), Group rocuronium (n=44), or Group mivacurium (n=44). Each drug (cisatracurium 0.1 mg kg. Both ipsi-operative and control-operative IOP at T1, T2, and T3 significantly decreased from the baseline values (T0) in all three groups (. Bilateral IOP significantly decreased from the baseline values in all three groups during the induction phase. Cisatracurium, rocuronium, and mivacurium did not induce significant changes in bilateral IOP.

Topics: Adolescent; Adult; Aged; Anesthesia, General; Atracurium; Corneal Injuries; Diabetic Retinopathy; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Middle Aged; Mivacurium; Ophthalmologic Surgical Procedures; Prospective Studies; Rocuronium; Young Adult