miuraenamide-a and Neoplasms

miuraenamide-a has been researched along with Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for miuraenamide-a and Neoplasms

Article	Year
Total syntheses and biological evaluation of miuraenamides. Angewandte Chemie (International ed. in English), 2015, Apr-07, Volume: 54, Issue:15 The miuraenamides, relatively simple representatives of a class of cyclodepsipeptides with high antitumor activity, can be easily and flexibly obtained by the concept of peptide modification. A reaction sequence consisting of an aldol reaction, oxidation, and methylation of the glycine subunit of the cyclodepsipeptides allows the incorporation of the unusual α,β-unsaturated dehydroamino acid in one of the last steps of the synthesis. Topics: Actins; Antineoplastic Agents; Cell Line, Tumor; Depsipeptides; Humans; Methylation; Neoplasms; Oxidation-Reduction	2015

Article

Year

Total syntheses and biological evaluation of miuraenamides.

Angewandte Chemie (International ed. in English), 2015, Apr-07, Volume: 54, Issue:15

The miuraenamides, relatively simple representatives of a class of cyclodepsipeptides with high antitumor activity, can be easily and flexibly obtained by the concept of peptide modification. A reaction sequence consisting of an aldol reaction, oxidation, and methylation of the glycine subunit of the cyclodepsipeptides allows the incorporation of the unusual α,β-unsaturated dehydroamino acid in one of the last steps of the synthesis.

Topics: Actins; Antineoplastic Agents; Cell Line, Tumor; Depsipeptides; Humans; Methylation; Neoplasms; Oxidation-Reduction

2015