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mitoxantrone and Uterine Neoplasms

mitoxantrone has been researched along with Uterine Neoplasms in 12 studies

Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.

Uterine Neoplasms: Tumors or cancer of the UTERUS.

Research Excerpts

ExcerptRelevanceReference
"Twenty-nine evaluable patients with metastatic or recurrent leiomyosarcoma or malignant mixed mesodermal tumors of the uterus were treated with mitoxantrone 12 mg/m2 every 3 weeks."5.06Mitoxantrone in the treatment of advanced uterine sarcoma. A phase II trial of the Gynecologic Oncology Group. ( Adcock, L; Beecham, J; Bundy, BN; Muss, HB, 1990)
" As a functional consequence, knockdown of BCRP by siRNAs increased the sensitivity of human choriocarcinoma BeWo cells to mitoxantrone and topotecan by 10."3.72Modulation of breast cancer resistance protein (BCRP/ABCG2) gene expression using RNA interference. ( Beck, WT; Ee, PL; He, X; Ross, DD, 2004)
"35 ovarian cancer patients with ascites have been treated intraperitoneally with mitomycin C or mitoxantrone or interferon beta or tumor necrosis factor (TNF)."3.68[Locoregional ascites therapy with cytostatic drugs and immune modulators in gynecologic neoplasms]. ( Chronides, A; Diedrich, K; Krebs, D; Mallmann, P; Wagner, U; Werner, A, 1991)
"Mitoxantrone was administered to 12 patients with advanced or recurrent endometrial carcinoma of whom only 1 had received prior chemotherapy (chlorambucil)."1.27Phase II study of mitoxantrone in advanced or metastatic endometrial carcinoma. ( Boadle, DJ; Tattersall, MH, 1987)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's4 (33.33)18.2507
2000's2 (16.67)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yu, P1
Diao, W1
Jiang, X1
Chandacham, A1
Kietpeerakool, C1
Khunamornpong, S1
Suprasert, P1
Srisomboon, J1
Charoenkwan, K1
Phongnarisorn, C1
Cheewakraingkrai, C1
Siriaree, S1
Tantipalakorn, C1
Ee, PL1
He, X1
Ross, DD1
Beck, WT1
Görich, J1
Brensing, KA1
Kunze, V1
Sokiranski, R1
Rilinger, N1
Müller-Miny, H1
Brambs, HJ1
Werner, A2
Mallmann, P1
Chronides, A1
Diedrich, K2
Wagner, U1
Krebs, D2
Veenhof, KH1
George, M1
Forni, M1
Tumolo, S1
Rotmensz, N1
Vermorken, JB1
Muss, HB2
Bundy, BN2
Adcock, L1
Beecham, J1
Runge, HM1
Meerpohl, HG1
Pfleiderer, A1
Bode, U1
Musch, E1
Boadle, DJ1
Tattersall, MH1
DiSaia, PJ1
Ehrlich, CE1
Hilgers, RD1
Von Hoff, DD1
Stephens, RL1
Boutselis, JG1
Rivkin, SE1

Trials

1 trial available for mitoxantrone and Uterine Neoplasms

ArticleYear
Mitoxantrone in the treatment of advanced uterine sarcoma. A phase II trial of the Gynecologic Oncology Group.
    American journal of clinical oncology, 1990, Volume: 13, Issue:1

    Topics: Adult; Aged; Drug Evaluation; Female; Humans; Leiomyosarcoma; Middle Aged; Mitoxantrone; Multicenter

1990

Other Studies

11 other studies available for mitoxantrone and Uterine Neoplasms

ArticleYear
A Successfully Treated Metastatic Choriocarcinoma Coexistent With Pregnancy: A Case Report of a 4-Year Follow-Up.
    Medicine, 2016, Volume: 95, Issue:21

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cesarean Section; Choriocarcinoma; Cyclophosp

2016
Successfully conservative treatment of large cervical choriocarcinoma with profuse vaginal bleeding.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2009, Volume: 92, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Cytarabine; Diagnosis, Diffe

2009
Modulation of breast cancer resistance protein (BCRP/ABCG2) gene expression using RNA interference.
    Molecular cancer therapeutics, 2004, Volume: 3, Issue:12

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette

2004
[Percutaneous drainage of refractory necrotizing tumors: experience in 9 patients].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1995, Volume: 163, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Cystadenocarcinoma; Drainage; Female; His

1995
[Locoregional ascites therapy with cytostatic drugs and immune modulators in gynecologic neoplasms].
    Zentralblatt fur Gynakologie, 1991, Volume: 113, Issue:23

    Topics: Ascites; Breast Neoplasms; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Interferon-

1991
Mitoxantrone in advanced and/or recurrent endometrial carcinoma.
    European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:5

    Topics: Adenocarcinoma; Aged; Drug Evaluation; Female; Humans; Middle Aged; Mitoxantrone; Uterine Neoplasms

1990
Mitoxantrone therapy of advanced adenocarcinoma of the endometrium. A phase II trial.
    Onkologie, 1989, Volume: 12, Issue:2

    Topics: Adenocarcinoma; Aged; Drug Evaluation; Female; Follow-Up Studies; Humans; Middle Aged; Mitoxantrone;

1989
[Tolerance of intraoperative, intraperitoneal chemotherapy in advanced gynecologic malignancies].
    Geburtshilfe und Frauenheilkunde, 1988, Volume: 48, Issue:8

    Topics: Adolescent; Adult; Aged; Chemotherapy, Cancer, Regional Perfusion; Combined Modality Therapy; Female

1988
Phase II study of mitoxantrone in advanced or metastatic endometrial carcinoma.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1987, Volume: 27, Issue:4

    Topics: Adenocarcinoma; Aged; Drug Evaluation; Female; Humans; Middle Aged; Mitoxantrone; Neoplasm Recurrenc

1987
Mitoxantrone for carcinoma of the endometrium: a phase II trial of the Gynecologic Oncology Group.
    Cancer treatment reports, 1987, Volume: 71, Issue:2

    Topics: Adult; Aged; Drug Evaluation; Female; Humans; Middle Aged; Mitoxantrone; Neoplasm Metastasis; Uterin

1987
Mitoxantrone in adenocarcinoma of the endometrium: a Southwest Oncology Group Study.
    Cancer treatment reports, 1985, Volume: 69, Issue:11

    Topics: Adenocarcinoma; Aged; Anthraquinones; Endometrium; Female; Humans; Middle Aged; Mitoxantrone; Uterin

1985