mitoxantrone has been researched along with Renal Insufficiency in 3 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-one patients with ovarian cancer who had failed chemotherapy were treated, 24 at the MTD." | 6.68 | A phase I-II study of high-dose melphalan, mitoxantrone and carboplatin with peripheral blood stem cell support in patients with advanced ovarian or breast carcinoma. ( Baldwin, P; Buckner, CD; Greco, FA; Hainsworth, JD; Lewis, M; Schwartzberg, L; Weaver, CH; West, WH; Wittlin, F; Zhen, B, 1997) |
| "Thirty-one patients with ovarian cancer who had failed chemotherapy were treated, 24 at the MTD." | 2.68 | A phase I-II study of high-dose melphalan, mitoxantrone and carboplatin with peripheral blood stem cell support in patients with advanced ovarian or breast carcinoma. ( Baldwin, P; Buckner, CD; Greco, FA; Hainsworth, JD; Lewis, M; Schwartzberg, L; Weaver, CH; West, WH; Wittlin, F; Zhen, B, 1997) |
| " Mitoxantrone plasma samples were obtained prior to dosing and at 0, 0." | 1.28 | Distribution characteristics of mitoxantrone in a patient undergoing hemodialysis. ( Battaglia, AC; Boros, L; Cacek, T; Pine, RB, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amine, B | 1 |
| Benbouazza, K | 1 |
| Harzy, T | 1 |
| Rahmouni, R | 1 |
| Guedira, N | 1 |
| Lazrak, N | 1 |
| Hajjaj-Hassouni, N | 1 |
| Weaver, CH | 1 |
| Greco, FA | 1 |
| Hainsworth, JD | 1 |
| Zhen, B | 1 |
| Baldwin, P | 1 |
| Wittlin, F | 1 |
| Lewis, M | 1 |
| West, WH | 1 |
| Schwartzberg, L | 1 |
| Buckner, CD | 1 |
| Boros, L | 1 |
| Cacek, T | 1 |
| Pine, RB | 1 |
| Battaglia, AC | 1 |
1 trial available for mitoxantrone and Renal Insufficiency
| Article | Year |
|---|---|
A phase I-II study of high-dose melphalan, mitoxantrone and carboplatin with peripheral blood stem cell support in patients with advanced ovarian or breast carcinoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Breast Neoplasms; Carbo | 1997 |
2 other studies available for mitoxantrone and Renal Insufficiency
| Article | Year |
|---|---|
IgD kappa myeloma: a new case.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Humans; Hypercalcemia; Immunoglobulin | 2004 |
Distribution characteristics of mitoxantrone in a patient undergoing hemodialysis.
Topics: Aged; Female; Humans; Lymphoma; Mitoxantrone; Renal Dialysis; Renal Insufficiency; Time Factors; Tis | 1992 |