mitoxantrone has been researched along with Pleural Effusion in 6 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
Pleural Effusion: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.
| Excerpt | Relevance | Reference |
|---|---|---|
| "From 11/87 until 7/90 103 patients entered a prospective randomized trial on the treatment of malignant pleural effusions (MPE) with intrapleural mitoxantrone versus placebo (pleural tube alone with instillation of isotonic NaCl)." | 9.07 | Intrapleural palliative treatment of malignant pleural effusions with mitoxantrone versus placebo (pleural tube alone). ( Gatzemeier, U; Groth, G; Häussingen, K; Heckmayr, M; Magnussen, H; Neuhauss, R; Pavel, JV, 1991) |
| "Mitoxantrone, an anthracenedione, has been shown to be as effective as doxorubicin, but with less local or systemic toxicity, when used for the treatment of advanced breast cancer." | 9.06 | [Efficacy and toxicity of intrapleural mitoxantrone: apropos of 18 cases of pleural metastases of breast cancer]. ( Brun, B; Calitchi, E; Feuilhade, F; Haddad, E; Le Bourgeois, JP; Otzmeguine, Y; Pierquin, B, 1989) |
| "From 11/87 until 7/90 103 patients entered a prospective randomized trial on the treatment of malignant pleural effusions (MPE) with intrapleural mitoxantrone versus placebo (pleural tube alone with instillation of isotonic NaCl)." | 5.07 | Intrapleural palliative treatment of malignant pleural effusions with mitoxantrone versus placebo (pleural tube alone). ( Gatzemeier, U; Groth, G; Häussingen, K; Heckmayr, M; Magnussen, H; Neuhauss, R; Pavel, JV, 1991) |
| "Mitoxantrone, an anthracenedione, has been shown to be as effective as doxorubicin, but with less local or systemic toxicity, when used for the treatment of advanced breast cancer." | 5.06 | [Efficacy and toxicity of intrapleural mitoxantrone: apropos of 18 cases of pleural metastases of breast cancer]. ( Brun, B; Calitchi, E; Feuilhade, F; Haddad, E; Le Bourgeois, JP; Otzmeguine, Y; Pierquin, B, 1989) |
| "Mitoxantrone, 1." | 1.30 | Acute and chronic pleural changes after the intrapleural instillation of mitoxantrone in rabbits. ( Antonangelo, L; Light, RW; Silva, LM; Strunz, CM; Teixeira, LR; Vargas, FS, 1998) |
| "Pleural effusions are a frequent complication of malignant gynecologic diseases, especially in breast cancer with an incidence of about 50%." | 1.28 | [Local treatment of malignant pleural effusion in gynecologic tumors]. ( Kuhn, W; Musch, E; Seitzer, D, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Franke, M | 1 |
| Theurich, S | 1 |
| Beyer, F | 1 |
| Persigehl, T | 1 |
| Vargas, FS | 1 |
| Teixeira, LR | 1 |
| Antonangelo, L | 1 |
| Silva, LM | 1 |
| Strunz, CM | 1 |
| Light, RW | 1 |
| Seitzer, D | 1 |
| Musch, E | 1 |
| Kuhn, W | 1 |
| Groth, G | 1 |
| Gatzemeier, U | 1 |
| Häussingen, K | 1 |
| Heckmayr, M | 1 |
| Magnussen, H | 1 |
| Neuhauss, R | 1 |
| Pavel, JV | 1 |
| Green, AR | 1 |
| Campbell, IA | 1 |
| Poynton, C | 1 |
| Bentley, DP | 1 |
| Feuilhade, F | 1 |
| Brun, B | 1 |
| Calitchi, E | 1 |
| Otzmeguine, Y | 1 |
| Haddad, E | 1 |
| Le Bourgeois, JP | 1 |
| Pierquin, B | 1 |
2 trials available for mitoxantrone and Pleural Effusion
| Article | Year |
|---|---|
Intrapleural palliative treatment of malignant pleural effusions with mitoxantrone versus placebo (pleural tube alone).
Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Mitoxantrone; Neoplasms; Palliati | 1991 |
[Efficacy and toxicity of intrapleural mitoxantrone: apropos of 18 cases of pleural metastases of breast cancer].
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Injectio | 1989 |
4 other studies available for mitoxantrone and Pleural Effusion
| Article | Year |
|---|---|
[Pulmonary differentiation -/ATRA syndrome within the scope of therapy of acute promyelocytic leukemia (APL)].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Diagnosis, Differential; D | 2014 |
Acute and chronic pleural changes after the intrapleural instillation of mitoxantrone in rabbits.
Topics: Animals; Instillation, Drug; Male; Mitoxantrone; Pleura; Pleural Effusion; Pleurodesis; Rabbits; Tim | 1998 |
[Local treatment of malignant pleural effusion in gynecologic tumors].
Topics: Breast Neoplasms; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Mitoxantrone; Ovaria | 1990 |
Acute myeloid leukaemia presenting with pleural effusions.
Topics: Antigens, Differentiation; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Cytar | 1989 |