mitoxantrone has been researched along with Osteogenic Sarcoma in 7 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
Excerpt | Relevance | Reference |
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" To determine whether IL-6 or IL-8 overexpression contributes directly to the drug resistant phenotype, IL-6 or IL-8 cDNA were introduced into the paclitaxel sensitive human osteosarcoma cell line U-2OS using the pIRESneo bicistronic expression vector." | 7.71 | Overexpression of IL-6 but not IL-8 increases paclitaxel resistance of U-2OS human osteosarcoma cells. ( Duan, Z; Kronish, KM; Lamendola, DE; Penson, RT; Seiden, MV, 2002) |
" In particular, we found that treatment of U-2 OS osteosarcoma cells with the anthracycine daunorubicin or with ultraviolet (UV-C) light resulted in a form of NF-kappaB that repressed rather than induced NF-kappaB reporter plasmids and the expression of specific anti-apoptotic genes." | 3.73 | Differential regulation of NF-kappaB activation and function by topoisomerase II inhibitors. ( Campbell, KJ; O'Shea, JM; Perkins, ND, 2006) |
" To determine whether IL-6 or IL-8 overexpression contributes directly to the drug resistant phenotype, IL-6 or IL-8 cDNA were introduced into the paclitaxel sensitive human osteosarcoma cell line U-2OS using the pIRESneo bicistronic expression vector." | 3.71 | Overexpression of IL-6 but not IL-8 increases paclitaxel resistance of U-2OS human osteosarcoma cells. ( Duan, Z; Kronish, KM; Lamendola, DE; Penson, RT; Seiden, MV, 2002) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (14.29) | 18.7374 |
1990's | 1 (14.29) | 18.2507 |
2000's | 2 (28.57) | 29.6817 |
2010's | 3 (42.86) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Workenhe, ST | 1 |
Pol, JG | 1 |
Lichty, BD | 1 |
Cummings, DT | 1 |
Mossman, KL | 1 |
Gopinath, SC | 1 |
Wadhwa, R | 1 |
Kumar, PK | 1 |
Zhang, F | 1 |
Throm, SL | 1 |
Murley, LL | 1 |
Miller, LA | 1 |
Steven Zatechka, D | 1 |
Kiplin Guy, R | 1 |
Kennedy, R | 1 |
Stewart, CF | 1 |
Campbell, KJ | 1 |
O'Shea, JM | 1 |
Perkins, ND | 1 |
Moser, K | 1 |
Pohl, A | 1 |
Ogilvie, GK | 1 |
Straw, RC | 1 |
Jameson, VJ | 1 |
Walters, LM | 1 |
Lafferty, MH | 1 |
Powers, BE | 1 |
Withrow, SJ | 1 |
Duan, Z | 1 |
Lamendola, DE | 1 |
Penson, RT | 1 |
Kronish, KM | 1 |
Seiden, MV | 1 |
1 review available for mitoxantrone and Osteogenic Sarcoma
Article | Year |
---|---|
[Recent developments in chemotherapy of malignant diseases].
Topics: Anthraquinones; Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy | 1982 |
6 other studies available for mitoxantrone and Osteogenic Sarcoma
Article | Year |
---|---|
Combining oncolytic HSV-1 with immunogenic cell death-inducing drug mitoxantrone breaks cancer immune tolerance and improves therapeutic efficacy.
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; CD8-Positive T-Lymphocytes; Cell Death; Cell Line, T | 2013 |
Expression of noncoding vault RNA in human malignant cells and its importance in mitoxantrone resistance.
Topics: Antineoplastic Agents; Base Sequence; Bone Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; G | 2010 |
MDM2 antagonist nutlin-3a reverses mitoxantrone resistance by inhibiting breast cancer resistance protein mediated drug transport.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette | 2011 |
Differential regulation of NF-kappaB activation and function by topoisomerase II inhibitors.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Catechin; Cell Line, Tumor; Daunorubicin; DNA Da | 2006 |
Evaluation of single-agent chemotherapy for treatment of clinically evident osteosarcoma metastases in dogs: 45 cases (1987-1991).
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Dog Diseases; Dog | 1993 |
Overexpression of IL-6 but not IL-8 increases paclitaxel resistance of U-2OS human osteosarcoma cells.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamil | 2002 |