mitoxantrone has been researched along with Osteogenic Sarcoma in 7 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To determine whether IL-6 or IL-8 overexpression contributes directly to the drug resistant phenotype, IL-6 or IL-8 cDNA were introduced into the paclitaxel sensitive human osteosarcoma cell line U-2OS using the pIRESneo bicistronic expression vector." | 7.71 | Overexpression of IL-6 but not IL-8 increases paclitaxel resistance of U-2OS human osteosarcoma cells. ( Duan, Z; Kronish, KM; Lamendola, DE; Penson, RT; Seiden, MV, 2002) |
| " In particular, we found that treatment of U-2 OS osteosarcoma cells with the anthracycine daunorubicin or with ultraviolet (UV-C) light resulted in a form of NF-kappaB that repressed rather than induced NF-kappaB reporter plasmids and the expression of specific anti-apoptotic genes." | 3.73 | Differential regulation of NF-kappaB activation and function by topoisomerase II inhibitors. ( Campbell, KJ; O'Shea, JM; Perkins, ND, 2006) |
| " To determine whether IL-6 or IL-8 overexpression contributes directly to the drug resistant phenotype, IL-6 or IL-8 cDNA were introduced into the paclitaxel sensitive human osteosarcoma cell line U-2OS using the pIRESneo bicistronic expression vector." | 3.71 | Overexpression of IL-6 but not IL-8 increases paclitaxel resistance of U-2OS human osteosarcoma cells. ( Duan, Z; Kronish, KM; Lamendola, DE; Penson, RT; Seiden, MV, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Workenhe, ST | 1 |
| Pol, JG | 1 |
| Lichty, BD | 1 |
| Cummings, DT | 1 |
| Mossman, KL | 1 |
| Gopinath, SC | 1 |
| Wadhwa, R | 1 |
| Kumar, PK | 1 |
| Zhang, F | 1 |
| Throm, SL | 1 |
| Murley, LL | 1 |
| Miller, LA | 1 |
| Steven Zatechka, D | 1 |
| Kiplin Guy, R | 1 |
| Kennedy, R | 1 |
| Stewart, CF | 1 |
| Campbell, KJ | 1 |
| O'Shea, JM | 1 |
| Perkins, ND | 1 |
| Moser, K | 1 |
| Pohl, A | 1 |
| Ogilvie, GK | 1 |
| Straw, RC | 1 |
| Jameson, VJ | 1 |
| Walters, LM | 1 |
| Lafferty, MH | 1 |
| Powers, BE | 1 |
| Withrow, SJ | 1 |
| Duan, Z | 1 |
| Lamendola, DE | 1 |
| Penson, RT | 1 |
| Kronish, KM | 1 |
| Seiden, MV | 1 |
1 review available for mitoxantrone and Osteogenic Sarcoma
| Article | Year |
|---|---|
[Recent developments in chemotherapy of malignant diseases].
Topics: Anthraquinones; Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy | 1982 |
6 other studies available for mitoxantrone and Osteogenic Sarcoma
| Article | Year |
|---|---|
Combining oncolytic HSV-1 with immunogenic cell death-inducing drug mitoxantrone breaks cancer immune tolerance and improves therapeutic efficacy.
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; CD8-Positive T-Lymphocytes; Cell Death; Cell Line, T | 2013 |
Expression of noncoding vault RNA in human malignant cells and its importance in mitoxantrone resistance.
Topics: Antineoplastic Agents; Base Sequence; Bone Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; G | 2010 |
MDM2 antagonist nutlin-3a reverses mitoxantrone resistance by inhibiting breast cancer resistance protein mediated drug transport.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette | 2011 |
Differential regulation of NF-kappaB activation and function by topoisomerase II inhibitors.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Catechin; Cell Line, Tumor; Daunorubicin; DNA Da | 2006 |
Evaluation of single-agent chemotherapy for treatment of clinically evident osteosarcoma metastases in dogs: 45 cases (1987-1991).
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Dog Diseases; Dog | 1993 |
Overexpression of IL-6 but not IL-8 increases paclitaxel resistance of U-2OS human osteosarcoma cells.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamil | 2002 |