mitoxantrone has been researched along with Opportunistic Infections in 10 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
Opportunistic Infections: An infection caused by an organism which becomes pathogenic under certain conditions, e.g., during immunosuppression.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty-one patients with recurrent or refractory indolent lymphoma were treated with a regimen of fludarabine 25 mg/m2/d intravenously (IV) on days 1 to 3, mitoxantrone 10 mg/m2 IV on day 1, and dexamethasone 20 mg/d IV or orally on days 1 to 5." | 9.08 | Fludarabine, mitoxantrone, and dexamethasone: an effective new regimen for indolent lymphoma. ( Cabanillas, F; Hagemeister, FB; Keating, M; McLaughlin, P; Pate, O; Romaguera, JE; Sarris, AH; Swan, F; Younes, A, 1996) |
| "54 patients with advanced breast cancer were randomised into a prospective, non-blinded, controlled trial to receive: mitoxantrone 28 mg/m2 intravenous day 1 and granulocyte-colony stimulating factor (G-CSF) 5 micrograms/kg/day subcutaneously days 2 to 16 (n = 27) or the same regimen plus thymostimulin (TS) 50 mg/day intramuscular at days 2 to 16 (n = 27)." | 9.08 | A randomised study comparing granulocyte-colony stimulating factor (G-CSF) with G-CSF plus thymostimulin in the treatment of haematological toxicity in patients with advanced breast cancer after high dose mitoxantrone therapy. ( Milla, A; Sanchiz, F, 1996) |
| " We report here on the unusual case of a patient with acute myelogenous leukemia and zygomycosis unresponsive to monotherapy with liposomal amphotericin B, who responded favorably following the addition of the echinocandin caspofungin acetate." | 7.73 | Successful treatment of rhinocerebral zygomycosis with a combination of caspofungin and liposomal amphotericin B. ( Caballero, D; Mateos, JJ; Perez, E; San Miguel, JF; Sanz-Rodriguez, C; Vazquez, L, 2005) |
| "Fifty-one patients with recurrent or refractory indolent lymphoma were treated with a regimen of fludarabine 25 mg/m2/d intravenously (IV) on days 1 to 3, mitoxantrone 10 mg/m2 IV on day 1, and dexamethasone 20 mg/d IV or orally on days 1 to 5." | 5.08 | Fludarabine, mitoxantrone, and dexamethasone: an effective new regimen for indolent lymphoma. ( Cabanillas, F; Hagemeister, FB; Keating, M; McLaughlin, P; Pate, O; Romaguera, JE; Sarris, AH; Swan, F; Younes, A, 1996) |
| "54 patients with advanced breast cancer were randomised into a prospective, non-blinded, controlled trial to receive: mitoxantrone 28 mg/m2 intravenous day 1 and granulocyte-colony stimulating factor (G-CSF) 5 micrograms/kg/day subcutaneously days 2 to 16 (n = 27) or the same regimen plus thymostimulin (TS) 50 mg/day intramuscular at days 2 to 16 (n = 27)." | 5.08 | A randomised study comparing granulocyte-colony stimulating factor (G-CSF) with G-CSF plus thymostimulin in the treatment of haematological toxicity in patients with advanced breast cancer after high dose mitoxantrone therapy. ( Milla, A; Sanchiz, F, 1996) |
| "A 64-year-old man with acute myelogenous leukemia (FAB classification, M7) in remission received consolidation chemotherapy with mitoxantrone/cytosine arabinoside." | 4.85 | [Bacillus cereus sepsis and subarachnoid hemorrhage following consolidation chemotherapy for acute myelogenous leukemia]. ( Gondo, H; Kawatani, E; Kishikawa, Y; Kuwahara, N; Matsuishi, E; Mori, D; Osoegawa, K; Sankoda, C, 2009) |
| " We report here on the unusual case of a patient with acute myelogenous leukemia and zygomycosis unresponsive to monotherapy with liposomal amphotericin B, who responded favorably following the addition of the echinocandin caspofungin acetate." | 3.73 | Successful treatment of rhinocerebral zygomycosis with a combination of caspofungin and liposomal amphotericin B. ( Caballero, D; Mateos, JJ; Perez, E; San Miguel, JF; Sanz-Rodriguez, C; Vazquez, L, 2005) |
| "A 23-year-old man with acute myelogenous leukemia (AML) (M2) who was pretreated with chemotherapy for autologous bone marrow transplantation developed a skin ulcer on the left groin." | 1.39 | Dermatic Scedosporium apiospermum infection after autologous bone marrow transplantation. ( Chen, H; Hu, J; Hu, L; Jiang, M; Li, B; Li, Y; Lou, X; Ning, H; Wang, J; Xu, C; Yu, Z, 2013) |
| "Mucormycosis is a rare fungal infection that has been described mainly in oncologic and diabetic patients." | 1.29 | [Pulmonary mucormycosis in leukemic patients. Apropos of 2 cases]. ( Cancelas, JA; Cerveró, C; García-Laraña, J; López, J; Navarro, JL; Odriozola, J; Pérez-Oteyza, J; Sánchez-Sousa, A; Sastre, JL, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, Z | 1 |
| Hu, L | 1 |
| Jiang, M | 1 |
| Ning, H | 1 |
| Xu, C | 1 |
| Li, B | 1 |
| Li, Y | 1 |
| Lou, X | 1 |
| Wang, J | 1 |
| Hu, J | 1 |
| Chen, H | 1 |
| Kawatani, E | 1 |
| Kishikawa, Y | 1 |
| Sankoda, C | 1 |
| Kuwahara, N | 1 |
| Mori, D | 1 |
| Osoegawa, K | 1 |
| Matsuishi, E | 1 |
| Gondo, H | 1 |
| Löfgren, C | 1 |
| Paul, C | 1 |
| Aström, M | 1 |
| Hast, R | 1 |
| Hedenius, M | 1 |
| Lerner, R | 1 |
| Liliemark, J | 1 |
| Nilsson, I | 1 |
| Rödjer, S | 1 |
| Simonsson, B | 1 |
| Stockelberg, D | 1 |
| Tidefelt, U | 1 |
| Björkholm, M | 1 |
| Köppler, H | 1 |
| Heymanns, J | 1 |
| Pandorf, A | 1 |
| Weide, R | 1 |
| Hendry, L | 1 |
| Bowen, A | 1 |
| Matutes, E | 1 |
| Swansbury, J | 1 |
| Catovsky, D | 1 |
| Vazquez, L | 1 |
| Mateos, JJ | 1 |
| Sanz-Rodriguez, C | 1 |
| Perez, E | 1 |
| Caballero, D | 1 |
| San Miguel, JF | 1 |
| Sastre, JL | 1 |
| Pérez-Oteyza, J | 1 |
| López, J | 1 |
| Cerveró, C | 1 |
| Sánchez-Sousa, A | 1 |
| García-Laraña, J | 1 |
| Cancelas, JA | 1 |
| Odriozola, J | 1 |
| Navarro, JL | 1 |
| McLaughlin, P | 1 |
| Hagemeister, FB | 1 |
| Romaguera, JE | 1 |
| Sarris, AH | 1 |
| Pate, O | 1 |
| Younes, A | 1 |
| Swan, F | 1 |
| Keating, M | 1 |
| Cabanillas, F | 1 |
| Sanchiz, F | 1 |
| Milla, A | 1 |
| Kern, W | 1 |
| Aul, C | 1 |
| Maschmeyer, G | 1 |
| Kuse, R | 1 |
| Kerkhoff, A | 1 |
| Grote-Metke, A | 1 |
| Eimermacher, H | 1 |
| Kubica, U | 1 |
| Wörmann, B | 1 |
| Büchner, T | 1 |
| Hiddemann, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I Trial of Autologous CLL B Cells Transduced to Express Chimeric CD154 (ISF35)[NCT00779883] | Phase 1 | 9 participants (Actual) | Interventional | 2006-06-30 | Completed | ||
| A Phase 1B Extension Trial to Allow Repeat Dosing of Autologous CLL B Cells Transduced to Express Chimeric CD154 (ISF35) in Subjects Previously Treated in MDACC Protocol 2004-0914[NCT00783588] | Phase 1 | 4 participants (Actual) | Interventional | 2007-05-31 | Completed | ||
| An Open Label, Multicenter, Non Randomized Phase II Study to Evaluate Anti-tumor Activity and Safety of a Combination of Fludarabine, Mitoxantrone and Rituximab in Relapsed or Primary Failing Advanced Follicular Non-Hodgkin's Lymphoma.[NCT00169208] | Phase 2 | 50 participants (Actual) | Interventional | 2001-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for mitoxantrone and Opportunistic Infections
| Article | Year |
|---|---|
[Bacillus cereus sepsis and subarachnoid hemorrhage following consolidation chemotherapy for acute myelogenous leukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bacillaceae Infections; Bacillus cereus; Cytarabine; | 2009 |
6 trials available for mitoxantrone and Opportunistic Infections
| Article | Year |
|---|---|
Granulocyte-macrophage colony-stimulating factor to increase efficacy of mitoxantrone, etoposide and cytarabine in previously untreated elderly patients with acute myeloid leukaemia: a Swedish multicentre randomized trial.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; | 2004 |
Bendamustine plus mitoxantrone--a new effective treatment for advanced chronic lymphocytic leukaemia: results of a phase I/II study.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; | 2004 |
Fludarabine, cyclophosphamide and mitoxantrone in relapsed or refractory chronic lymphocytic leukemia and low grade non-Hodgkin's lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration S | 2004 |
Fludarabine, cyclophosphamide and mitoxantrone in relapsed or refractory chronic lymphocytic leukemia and low grade non-Hodgkin's lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration S | 2004 |
Fludarabine, cyclophosphamide and mitoxantrone in relapsed or refractory chronic lymphocytic leukemia and low grade non-Hodgkin's lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration S | 2004 |
Fludarabine, cyclophosphamide and mitoxantrone in relapsed or refractory chronic lymphocytic leukemia and low grade non-Hodgkin's lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration S | 2004 |
Fludarabine, mitoxantrone, and dexamethasone: an effective new regimen for indolent lymphoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Female; Humans; Lymphoma; Male; | 1996 |
A randomised study comparing granulocyte-colony stimulating factor (G-CSF) with G-CSF plus thymostimulin in the treatment of haematological toxicity in patients with advanced breast cancer after high dose mitoxantrone therapy.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Drug Therapy, Combination; Female; Granulocyte Colon | 1996 |
Granulocyte colony-stimulating factor shortens duration of critical neutropenia and prolongs disease-free survival after sequential high-dose cytosine arabinoside and mitoxantrone (S-HAM) salvage therapy for refractory and relapsed acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Critical Car | 1998 |
3 other studies available for mitoxantrone and Opportunistic Infections
| Article | Year |
|---|---|
Dermatic Scedosporium apiospermum infection after autologous bone marrow transplantation.
Topics: Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Comb | 2013 |
Successful treatment of rhinocerebral zygomycosis with a combination of caspofungin and liposomal amphotericin B.
Topics: Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Caspofungin; Comb | 2005 |
[Pulmonary mucormycosis in leukemic patients. Apropos of 2 cases].
Topics: Adult; Aged; Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Fatal Outco | 1994 |