mitoxantrone has been researched along with Nerve Degeneration in 4 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eleuteri, S | 1 |
| Di Giovanni, S | 1 |
| Rockenstein, E | 1 |
| Mante, M | 1 |
| Adame, A | 1 |
| Trejo, M | 1 |
| Wrasidlo, W | 1 |
| Wu, F | 1 |
| Fraering, PC | 1 |
| Masliah, E | 1 |
| Lashuel, HA | 1 |
| Kieseier, BC | 1 |
| Hartung, HP | 1 |
| Au, WY | 1 |
| Mak, W | 1 |
| Ho, SL | 1 |
| Leung, SY | 1 |
| Kwong, YL | 1 |
| Morrissey, SP | 1 |
| Le Page, E | 1 |
| Edan, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II Proof of Concept Study Evaluating the Reduction of Mitoxantrone-induced Cardiotoxicity and Neurological Outcome in the Combined Use of Mitoxantrone and Dexrazoxane (Cardioxane®) in Multiple Sclerosis (MSCardioPro)[NCT01627938] | Phase 2 | 50 participants (Anticipated) | Interventional | 2012-04-30 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for mitoxantrone and Nerve Degeneration
| Article | Year |
|---|---|
Multiple paradigm shifts in multiple sclerosis.
Topics: Adjuvants, Immunologic; Clinical Trials as Topic; Humans; Inflammation; Interferon-beta; Mitoxantron | 2003 |
Mitoxantrone in the treatment of multiple sclerosis.
Topics: Antineoplastic Agents; Axons; Humans; Mitoxantrone; Multiple Sclerosis; Nerve Degeneration | 2005 |
2 other studies available for mitoxantrone and Nerve Degeneration
| Article | Year |
|---|---|
Novel therapeutic strategy for neurodegeneration by blocking Aβ seeding mediated aggregation in models of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Bithionol; Cells, | 2015 |
Reversible paraneoplastic neuropathy associated with T-cell large granular lymphocyte leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cyclosporine; Dexamethasone; Female; Humans; | 2004 |