mitoxantrone has been researched along with Neoplasms, Pleural in 12 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We performed a multicenter phase II trial to evaluate the impact on the activity, efficacy, symptom control and safety of using two active regimens in a sequential schedule (cisplatin/gemcitabine followed by mitoxantrone/methotrexate/mitomycin) as first-line chemotherapy for unresectable malignant pleural mesothelioma (MPM)." | 9.12 | Sequential chemotherapy with cisplatin/gemcitabine (CG) followed by mitoxantrone/methotrexate/mitomycin (MMM) in patients with malignant pleural mesothelioma. A multicenter Italian Phase II Study (SITMP1). ( Benedetti, G; De Pangher Manzini, V; Del Conte, G; dell'Amore, D; Galetta, D; Giaquinta, S; Lopez, M; Marino, A; Martoni, A; Mazzanti, P; Piana, E; Pinto, C, 2006) |
| "Mitoxantrone, an anthracenedione, has been shown to be as effective as doxorubicin, but with less local or systemic toxicity, when used for the treatment of advanced breast cancer." | 9.06 | [Efficacy and toxicity of intrapleural mitoxantrone: apropos of 18 cases of pleural metastases of breast cancer]. ( Brun, B; Calitchi, E; Feuilhade, F; Haddad, E; Le Bourgeois, JP; Otzmeguine, Y; Pierquin, B, 1989) |
| "46 patients with malignant pleural mesothelioma were entered in a phase II study of mitoxantrone 14 mg/m2 every 3 weeks." | 7.68 | Mitoxantrone in malignant pleural mesothelioma: a study by the EORTC Lung Cancer Cooperative Group. ( Dalesio, O; Giaccone, G; Kirkpatrick, A; Mattson, K; Planteydt, HT; van Breukelen, FJ; van Zandwijk, N, 1991) |
| "We performed a multicenter phase II trial to evaluate the impact on the activity, efficacy, symptom control and safety of using two active regimens in a sequential schedule (cisplatin/gemcitabine followed by mitoxantrone/methotrexate/mitomycin) as first-line chemotherapy for unresectable malignant pleural mesothelioma (MPM)." | 5.12 | Sequential chemotherapy with cisplatin/gemcitabine (CG) followed by mitoxantrone/methotrexate/mitomycin (MMM) in patients with malignant pleural mesothelioma. A multicenter Italian Phase II Study (SITMP1). ( Benedetti, G; De Pangher Manzini, V; Del Conte, G; dell'Amore, D; Galetta, D; Giaquinta, S; Lopez, M; Marino, A; Martoni, A; Mazzanti, P; Piana, E; Pinto, C, 2006) |
| "Thirty cases (breast cancer-20 cases, malignant lymphoma-4 cases, different malignancies-6 cases) of histologically/cytologically verified malignant pleural effusion (MPE) in 29 patients were treated with intrapleurally instilled mitoxantrone (30 mg)." | 5.08 | Intrapleurally instilled mitoxantrone in metastatic pleural effusions: a phase II study. ( Aasebø, U; Norum, J; Sager, G; Slørdal, L, 1997) |
| "Mitoxantrone, an anthracenedione, has been shown to be as effective as doxorubicin, but with less local or systemic toxicity, when used for the treatment of advanced breast cancer." | 5.06 | [Efficacy and toxicity of intrapleural mitoxantrone: apropos of 18 cases of pleural metastases of breast cancer]. ( Brun, B; Calitchi, E; Feuilhade, F; Haddad, E; Le Bourgeois, JP; Otzmeguine, Y; Pierquin, B, 1989) |
| "46 patients with malignant pleural mesothelioma were entered in a phase II study of mitoxantrone 14 mg/m2 every 3 weeks." | 3.68 | Mitoxantrone in malignant pleural mesothelioma: a study by the EORTC Lung Cancer Cooperative Group. ( Dalesio, O; Giaccone, G; Kirkpatrick, A; Mattson, K; Planteydt, HT; van Breukelen, FJ; van Zandwijk, N, 1991) |
| "Pleural effusions are a frequent complication of malignant gynecologic diseases, especially in breast cancer with an incidence of about 50%." | 1.28 | [Local treatment of malignant pleural effusion in gynecologic tumors]. ( Kuhn, W; Musch, E; Seitzer, D, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fischer, B | 1 |
| Frei, C | 1 |
| Moura, U | 1 |
| Stahel, R | 1 |
| Felley-Bosco, E | 1 |
| Pinto, C | 2 |
| Marino, A | 2 |
| De Pangher Manzini, V | 1 |
| Benedetti, G | 1 |
| Galetta, D | 1 |
| Mazzanti, P | 1 |
| Del Conte, G | 1 |
| dell'Amore, D | 1 |
| Piana, E | 2 |
| Giaquinta, S | 1 |
| Lopez, M | 1 |
| Martoni, A | 2 |
| Aasebø, U | 1 |
| Norum, J | 1 |
| Sager, G | 1 |
| Slørdal, L | 1 |
| Krismann, M | 1 |
| Pieper, K | 1 |
| Müller, KM | 1 |
| Guaraldi, M | 1 |
| Melotti, B | 1 |
| Pannuti, F | 1 |
| Verschraegen, CF | 1 |
| Tejler, G | 1 |
| Seitzer, D | 1 |
| Musch, E | 1 |
| Kuhn, W | 1 |
| van Breukelen, FJ | 1 |
| Mattson, K | 1 |
| Giaccone, G | 1 |
| van Zandwijk, N | 1 |
| Planteydt, HT | 1 |
| Kirkpatrick, A | 1 |
| Dalesio, O | 1 |
| Kuhn, K | 1 |
| Purea, H | 1 |
| Selbach, J | 1 |
| Westerhausen, M | 1 |
| Feuilhade, F | 1 |
| Brun, B | 1 |
| Calitchi, E | 1 |
| Otzmeguine, Y | 1 |
| Haddad, E | 1 |
| Le Bourgeois, JP | 1 |
| Pierquin, B | 1 |
| Salzer, G | 1 |
1 review available for mitoxantrone and Neoplasms, Pleural
| Article | Year |
|---|---|
Intracavitary therapies for mesothelioma.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adj | 2001 |
4 trials available for mitoxantrone and Neoplasms, Pleural
| Article | Year |
|---|---|
Sequential chemotherapy with cisplatin/gemcitabine (CG) followed by mitoxantrone/methotrexate/mitomycin (MMM) in patients with malignant pleural mesothelioma. A multicenter Italian Phase II Study (SITMP1).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Drug Therapy, | 2006 |
Intrapleurally instilled mitoxantrone in metastatic pleural effusions: a phase II study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Breast Neoplasms; Chemotherapy, A | 1997 |
Combination chemotherapy with mitoxantrone, methotrexate, and mitomycin (MMM regimen) in malignant pleural mesothelioma: a phase II study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Male; Mesothelioma; Methotrexa | 2001 |
[Efficacy and toxicity of intrapleural mitoxantrone: apropos of 18 cases of pleural metastases of breast cancer].
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Injectio | 1989 |
7 other studies available for mitoxantrone and Neoplasms, Pleural
| Article | Year |
|---|---|
Inhibition of phosphoinositide-3 kinase pathway down regulates ABCG2 function and sensitizes malignant pleural mesothelioma to chemotherapy.
Topics: Androstadienes; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP- | 2012 |
[Pleural reaction pattern after talc pleurodesis].
Topics: Follow-Up Studies; Foreign-Body Reaction; Humans; Microscopy, Electron, Scanning; Mitoxantrone; Pleu | 1998 |
[Is intrapleural mitoxantrone treatment of pleural effusion effective in pleural metastasis from breast cancer?].
Topics: Aged; Breast Neoplasms; Drainage; Female; Humans; Mitoxantrone; Palliative Care; Pleural Effusion, M | 1992 |
[Local treatment of malignant pleural effusion in gynecologic tumors].
Topics: Breast Neoplasms; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Mitoxantrone; Ovaria | 1990 |
Mitoxantrone in malignant pleural mesothelioma: a study by the EORTC Lung Cancer Cooperative Group.
Topics: Adult; Aged; Drug Evaluation; Female; Humans; Leukopenia; Male; Mesothelioma; Middle Aged; Mitoxantr | 1991 |
Treatment with locally applied mitoxantrone.
Topics: Catheters, Indwelling; Female; Humans; Infusions, Parenteral; Male; Mediastinal Neoplasms; Mitoxantr | 1989 |
Pleura carcinosis. Cytomorphological findings with the mistletoe preparation iscador and other pharmaceuticals.
Topics: Antineoplastic Agents, Phytogenic; Doxorubicin; Humans; Mistletoe; Mitoxantrone; Phytotherapy; Picib | 1986 |