mitoxantrone has been researched along with Nasopharyngeal Neoplasms in 5 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
Nasopharyngeal Neoplasms: Tumors or cancer of the NASOPHARYNX.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mitoxantrone was administered intravenously at an initial dose of 12 mg/m2 and repeated every 3 weeks, with dose escalation to a maximum of 14 mg/m2." | 6.67 | Multicenter phase II trial of mitoxantrone in patients with advanced nasopharyngeal carcinoma in Southeast Asia: an Asian-Oceanian Clinical Oncology Association Group study. ( Choi, P; Choy, D; Dugan, M; Lee, S; Leung, T; Ngai, A; Prasad, U; Sham, J; Shiu, W; Teo, P, 1993) |
| "Mitoxantrone was administered intravenously at an initial dose of 12 mg/m2 and repeated every 3 weeks, with dose escalation to a maximum of 14 mg/m2." | 2.67 | Multicenter phase II trial of mitoxantrone in patients with advanced nasopharyngeal carcinoma in Southeast Asia: an Asian-Oceanian Clinical Oncology Association Group study. ( Choi, P; Choy, D; Dugan, M; Lee, S; Leung, T; Ngai, A; Prasad, U; Sham, J; Shiu, W; Teo, P, 1993) |
| " The pharmacokinetic parameters are described adequately by a three-compartment model with a terminal half-life of 71." | 2.38 | Pharmacokinetic and pharmacodynamic studies with mitoxantrone in the treatment of patients with nasopharyngeal carcinoma. ( Chang, SP; Chen, KY; Hu, OY; Jian, JM; Law, CK, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Witiak, DT | 1 |
| Kamat, PL | 1 |
| Allison, DL | 1 |
| Liebowitz, SM | 1 |
| Glaser, R | 1 |
| Holliday, JE | 1 |
| Moeschberger, ML | 1 |
| Schaller, JP | 1 |
| Wang, J | 1 |
| Guo, LP | 1 |
| Chen, LZ | 1 |
| Zeng, YX | 1 |
| Lu, SH | 1 |
| Dugan, M | 1 |
| Choy, D | 1 |
| Ngai, A | 1 |
| Sham, J | 1 |
| Choi, P | 1 |
| Shiu, W | 1 |
| Leung, T | 1 |
| Teo, P | 1 |
| Prasad, U | 1 |
| Lee, S | 1 |
| Hu, OY | 1 |
| Chang, SP | 1 |
| Law, CK | 1 |
| Jian, JM | 1 |
| Chen, KY | 1 |
| Ferguson, PJ | 1 |
| Cheng, YC | 1 |
1 review available for mitoxantrone and Nasopharyngeal Neoplasms
| Article | Year |
|---|---|
Pharmacokinetic and pharmacodynamic studies with mitoxantrone in the treatment of patients with nasopharyngeal carcinoma.
Topics: Adult; Chromatography, High Pressure Liquid; Female; Humans; Male; Metabolic Clearance Rate; Middle | 1992 |
1 trial available for mitoxantrone and Nasopharyngeal Neoplasms
| Article | Year |
|---|---|
Multicenter phase II trial of mitoxantrone in patients with advanced nasopharyngeal carcinoma in Southeast Asia: an Asian-Oceanian Clinical Oncology Association Group study.
Topics: Adult; Aged; Carcinoma; Female; Hematologic Diseases; Humans; Male; Middle Aged; Mitoxantrone; Nasop | 1993 |
3 other studies available for mitoxantrone and Nasopharyngeal Neoplasms
| Article | Year |
|---|---|
Bis(bioreductive) alkylating agents: synthesis and biological activity in a nude mouse human carcinoma model.
Topics: Animals; Antineoplastic Agents; Benzoquinones; Burkitt Lymphoma; Cell Line; Cisplatin; Drug Resistan | 1983 |
Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; | 2007 |
Transient protection of cultured human cells against antitumor agents by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Antineoplastic Agents; Cell Division; Cell Survival; Cells, Cultured; Diglycerides; Dose-Response Re | 1987 |