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mitoxantrone and Mucositis, Oral

mitoxantrone has been researched along with Mucositis, Oral in 12 studies

Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.

Research Excerpts

ExcerptRelevanceReference
" A phase II study was performed at the MTD of paclitaxel in patients with doxorubicin/mitoxantrone-refractory metastatic breast cancer."9.07Paclitaxel in doxorubicin-refractory or mitoxantrone-refractory breast cancer: a phase I/II trial of 96-hour infusion. ( Bates, S; Berg, SL; Bryant, G; Fojo, A; Goldspiel, BR; Herdt, J; O'Shaughnessy, J; Steinberg, SM; Wilson, WH; Wittes, RE, 1994)
"Seventeen patients with relapsed or refractory acute nonlymphocytic leukemia were treated with 14 mg/m2 of mitoxantrone given in a 30-minute infusion daily for three days."7.67Mitoxantrone in relapsed or refractory acute nonlymphocytic leukemia. ( Ball, ED; Cornell, CJ; Cornwell, GG; McIntyre, OR; Mills, LE; O'Donnell, JF; Vredenburgh, JJ, 1988)
"Twenty-three patients with advanced breast cancer were treated with the combination of mitoxantrone and doxorubicin."7.67Combined mitoxantrone plus doxorubicin in the treatment of breast cancer. ( Lefebvre, BM; Maroun, JA; Perrault, DJ; Stewart, DJ, 1987)
"Results of first-line mitoxantrone chemotherapy for advanced breast cancer are presented."7.67First-line mitoxantrone chemotherapy for advanced breast cancer. ( Paterson, AH; Wilson, KS, 1986)
"Mitoxantrone was evaluated in a multi-institution trial to define the effective dose for treating acute leukemia, to evaluate its toxicity, and to assess the induction rates for the different types of acute leukemia."7.67Phase I-II trial of mitoxantrone in acute leukemia. ( Arlin, ZA; Armentrout, S; Cassileth, P; Coleman, M; Daghestani, A; Dukart, G; Gams, R; Schoch, I; Silver, R, 1985)
" A phase II study was performed at the MTD of paclitaxel in patients with doxorubicin/mitoxantrone-refractory metastatic breast cancer."5.07Paclitaxel in doxorubicin-refractory or mitoxantrone-refractory breast cancer: a phase I/II trial of 96-hour infusion. ( Bates, S; Berg, SL; Bryant, G; Fojo, A; Goldspiel, BR; Herdt, J; O'Shaughnessy, J; Steinberg, SM; Wilson, WH; Wittes, RE, 1994)
"Seventeen patients with relapsed or refractory acute nonlymphocytic leukemia were treated with 14 mg/m2 of mitoxantrone given in a 30-minute infusion daily for three days."3.67Mitoxantrone in relapsed or refractory acute nonlymphocytic leukemia. ( Ball, ED; Cornell, CJ; Cornwell, GG; McIntyre, OR; Mills, LE; O'Donnell, JF; Vredenburgh, JJ, 1988)
"Twenty-three patients with advanced breast cancer were treated with the combination of mitoxantrone and doxorubicin."3.67Combined mitoxantrone plus doxorubicin in the treatment of breast cancer. ( Lefebvre, BM; Maroun, JA; Perrault, DJ; Stewart, DJ, 1987)
"Results of first-line mitoxantrone chemotherapy for advanced breast cancer are presented."3.67First-line mitoxantrone chemotherapy for advanced breast cancer. ( Paterson, AH; Wilson, KS, 1986)
"Mitoxantrone was evaluated in a multi-institution trial to define the effective dose for treating acute leukemia, to evaluate its toxicity, and to assess the induction rates for the different types of acute leukemia."3.67Phase I-II trial of mitoxantrone in acute leukemia. ( Arlin, ZA; Armentrout, S; Cassileth, P; Coleman, M; Daghestani, A; Dukart, G; Gams, R; Schoch, I; Silver, R, 1985)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19904 (33.33)18.7374
1990's3 (25.00)18.2507
2000's5 (41.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
van Vliet, MJ1
Tissing, WJ1
Rings, EH1
Koetse, HA1
Stellaard, F1
Kamps, WA1
de Bont, ES1
Apostolidou, E1
Estey, E1
Cortes, J1
Garcia-Manero, G1
Faderl, S1
Thomas, D1
Tsimberidou, A1
Kantarjian, H1
Giles, FJ1
Thomas, X1
Elhamri, M1
Chelghoum, Y1
Reman, O1
Arnaud, P1
Raffoux, E1
Le, QH1
Tavernier, E1
Dombret, H1
Michallet, M1
Wilson, WH1
Berg, SL1
Bryant, G1
Wittes, RE1
Bates, S1
Fojo, A1
Steinberg, SM1
Goldspiel, BR1
Herdt, J1
O'Shaughnessy, J1
Feldman, EJ1
Seiter, K1
Traganos, F1
Darzynkiewicz, Z1
Goff, H1
Pozzuoli, M1
Baskind, P1
Santos, S1
Ahmed, T1
Thurnher, D1
Kornfehl, J1
Burian, M1
Gedlicka, C1
Selzer, E1
Quint, C1
Neuchrist, C1
Kornek, GV1
Gherlinzoni, F1
Guglielmi, C1
Mazza, P1
Amadori, S1
Mandelli, F1
Tura, S1
Kreisle, WH1
Alberts, DS1
List, AF1
McCloskey, T1
Plezia, P1
Peng, YM1
George, M1
Vredenburgh, JJ1
McIntyre, OR1
Cornwell, GG1
Ball, ED1
Cornell, CJ1
Mills, LE1
O'Donnell, JF1
Stewart, DJ1
Perrault, DJ1
Maroun, JA1
Lefebvre, BM1
Wilson, KS1
Paterson, AH1
Arlin, ZA1
Silver, R1
Cassileth, P1
Armentrout, S1
Gams, R1
Daghestani, A1
Coleman, M1
Schoch, I1
Dukart, G1

Trials

8 trials available for mitoxantrone and Mucositis, Oral

ArticleYear
Citrulline as a marker for chemotherapy induced mucosal barrier injury in pediatric patients.
    Pediatric blood & cancer, 2009, Dec-15, Volume: 53, Issue:7

    Topics: Acute Disease; Adolescent; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Ca

2009
Mitoxantrone and prolonged infusion gemcitabine as salvage therapy in patients with acute myelogenous leukemia.
    Leukemia research, 2003, Volume: 27, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Deoxycytidine; Gemcitabine; Human

2003
Intensive chemotherapy with mitoxantrone administered as a single injection in patients with high-risk acute myeloid leukemia: results of the EMA 2000 trial.
    Annals of hematology, 2005, Volume: 84, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow

2005
Paclitaxel in doxorubicin-refractory or mitoxantrone-refractory breast cancer: a phase I/II trial of 96-hour infusion.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:8

    Topics: Adult; Aged; Agranulocytosis; Breast Neoplasms; Doxorubicin; Drug Administration Schedule; Drug Resi

1994
Phase II evaluation of a high-dose mitoxantrone based induction regimen in untreated adults with acute myeloid leukemia.
    Leukemia & lymphoma, 2000, Volume: 38, Issue:3-4

    Topics: Actuarial Analysis; Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marro

2000
Ifosfamide and mitoxantrone in the treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck.
    Anti-cancer drugs, 2001, Volume: 12, Issue:3

    Topics: Adult; Aged; Anemia; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Carcinoma,

2001
Phase III comparative trial (m-BACOD v m-BNCOD) in the treatment of stage II to IV non-Hodgkin's lymphomas with intermediate- or high-grade histology.
    Seminars in oncology, 1990, Volume: 17, Issue:6 Suppl 10

    Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide;

1990
A phase I trial of 14-day continuous intravenous infusion mitoxantrone.
    Anti-cancer drugs, 1991, Volume: 2, Issue:3

    Topics: Adult; Aged; Diarrhea; Drug Evaluation; Female; Gastrointestinal Diseases; Humans; Infusions, Intrav

1991

Other Studies

4 other studies available for mitoxantrone and Mucositis, Oral

ArticleYear
Mitoxantrone in relapsed or refractory acute nonlymphocytic leukemia.
    Medical and pediatric oncology, 1988, Volume: 16, Issue:3

    Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Drug Evaluation; Drug Resistance; Hema

1988
Combined mitoxantrone plus doxorubicin in the treatment of breast cancer.
    American journal of clinical oncology, 1987, Volume: 10, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Breast

1987
First-line mitoxantrone chemotherapy for advanced breast cancer.
    Cancer treatment reports, 1986, Volume: 70, Issue:8

    Topics: Adult; Aged; Anthraquinones; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols;

1986
Phase I-II trial of mitoxantrone in acute leukemia.
    Cancer treatment reports, 1985, Volume: 69, Issue:1

    Topics: Acute Disease; Adult; Aged; Anthraquinones; Drug Evaluation; Female; Heart; Humans; Leukemia; Leukem

1985