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mitoxantrone and Lymphoma, B-Cell, Marginal Zone

mitoxantrone has been researched along with Lymphoma, B-Cell, Marginal Zone in 12 studies

Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.

Lymphoma, B-Cell, Marginal Zone: Extranodal lymphoma of lymphoid tissue associated with mucosa that is in contact with exogenous antigens. Many of the sites of these lymphomas, such as the stomach, salivary gland, and thyroid, are normally devoid of lymphoid tissue. They acquire mucosa-associated lymphoid tissue (MALT) type as a result of an immunologically mediated disorder.

Research Excerpts

ExcerptRelevanceReference
"Patients with histologically verified MALT lymphoma undergoing chemotherapy with MCP were evaluated retrospectively."5.32Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) with mitoxantrone, chlorambucil and prednisone (MCP). ( Chott, A; Dirisamer, A; Drach, J; Hejna, M; Püspök, A; Raderer, M; Scheithauer, W; Wöhrer, S, 2003)
" The most common adverse effects were hematologic, with 2 patients experiencing treatment-related myelodysplastic syndrome (MDS), evolving to acute myelogenous leukemia (AML) in 1 patient."2.76Safety and efficacy of combination therapy with fludarabine, mitoxantrone, and rituximab followed by yttrium-90 ibritumomab tiuxetan and maintenance rituximab as front-line therapy for patients with follicular or marginal zone lymphoma. ( Bayer, R; Fung, HC; Gregory, SA; Karmali, R; Kassar, M; O'Brien, T; Shammo, JM; Venugopal, P, 2011)
"Cladribine is a newer purine analogue and is of particular interest because it is resistant to deamination by adenosine deaminase."2.42Treatment of indolent non-Hodgkin's lymphoma with cladribine as single-agent therapy and in combination with mitoxantrone. ( Armitage, JO; Hoelzer, D; Rummel, MJ; Tobinai, K, 2004)
"A 47 year old woman with a MALT lymphoma affecting the breast exclusively is reported."2.40[Primary MALT-type lymphoma of the breast]. ( Campo, E; Cervantes, F; Esteve, J; Montserrat, E; Rafel, M; Serra, A; Velasco, M, 1998)
"There were 32 small lymphocytic lymphomas and 111 marginal zone lymphomas."1.42Fludarabine-Mitoxantrone-Rituximab regimen in untreated indolent non-follicular non-Hodgkin's lymphoma: experience on 143 patients. ( Argnani, L; Broccoli, A; Casadei, B; Gandolfi, L; Maglie, R; Pellegrini, C; Pileri, S; Stefoni, V; Zinzani, PL, 2015)
"We present a patient with MALT lymphoma of the salivary glands who also had multiple calculi in the parotid glands."1.33Multiple bilateral parotid sialoliths in a patient with mucosa-associated lymphoid tissue lymphoma (MALT lymphoma) of the salivary glands. ( Drage, NA; Howarth, A; Wickramasinghe, A, 2005)
"As no data on this topic exist for MALT lymphoma, we have retrospectively analysed our experience with R plus cyclophosphamide, doxorubicin/mitoxantrone, vincristine and prednisone (R-CHOP/R-CNOP) in patients with relapsed MALT lymphoma."1.33Activity of rituximab plus cyclophosphamide, doxorubicin/mitoxantrone, vincristine and prednisone in patients with relapsed MALT lymphoma. ( Chott, A; Drach, J; Jager, U; Puspok, A; Raderer, M; Streubel, B; Troch, M; Turetschek, K; Wohrer, S; Zielinski, CC, 2006)
"Patients with histologically verified MALT lymphoma undergoing chemotherapy with MCP were evaluated retrospectively."1.32Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) with mitoxantrone, chlorambucil and prednisone (MCP). ( Chott, A; Dirisamer, A; Drach, J; Hejna, M; Püspök, A; Raderer, M; Scheithauer, W; Wöhrer, S, 2003)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's8 (66.67)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zinzani, PL2
Pellegrini, C2
Broccoli, A2
Gandolfi, L2
Stefoni, V2
Casadei, B2
Maglie, R1
Argnani, L2
Pileri, S2
Karmali, R1
Kassar, M1
Venugopal, P1
Shammo, JM1
Fung, HC1
Bayer, R1
O'Brien, T1
Gregory, SA1
Derenzini, E1
Quirini, F1
Celli, M1
Fanti, S1
Poletti, V1
Baccarani, M1
Wöhrer, S3
Drach, J3
Hejna, M2
Scheithauer, W1
Dirisamer, A1
Püspök, A2
Chott, A2
Raderer, M3
Armitage, JO1
Tobinai, K1
Hoelzer, D1
Rummel, MJ1
Wickramasinghe, A1
Howarth, A1
Drage, NA1
Bartsch, R1
Streubel, B1
Jager, U1
Turetschek, K1
Troch, M1
Zielinski, CC1
Roussel, B1
Bettembourg, O1
Cochard, C1
Cochener, B1
Economopoulos, T1
Psyrri, A1
Fountzilas, G1
Tsatalas, C1
Anagnostopoulos, A1
Papageorgiou, S1
Xiros, N1
Dimopoulos, MA1
Lü, SQ1
Yang, JM1
Song, XM1
Chen, L1
Zhang, WP1
Ni, X1
Xu, XQ1
Wang, JM1
Rafel, M1
Esteve, J1
Cervantes, F1
Velasco, M1
Serra, A1
Campo, E1
Montserrat, E1

Reviews

2 reviews available for mitoxantrone and Lymphoma, B-Cell, Marginal Zone

ArticleYear
Treatment of indolent non-Hodgkin's lymphoma with cladribine as single-agent therapy and in combination with mitoxantrone.
    International journal of hematology, 2004, Volume: 79, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cladribine; Humans; Leukemia, Lymphocytic, Chronic,

2004
[Primary MALT-type lymphoma of the breast].
    Sangre, 1998, Volume: 43, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cycloph

1998

Trials

2 trials available for mitoxantrone and Lymphoma, B-Cell, Marginal Zone

ArticleYear
Safety and efficacy of combination therapy with fludarabine, mitoxantrone, and rituximab followed by yttrium-90 ibritumomab tiuxetan and maintenance rituximab as front-line therapy for patients with follicular or marginal zone lymphoma.
    Clinical lymphoma, myeloma & leukemia, 2011, Volume: 11, Issue:6

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined

2011
Phase II study of low-grade non-Hodgkin lymphomas with fludarabine and mitoxantrone followed by rituximab consolidation: promising results in marginal zone lymphoma.
    Leukemia & lymphoma, 2008, Volume: 49, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Disease-Free Survival; Female; Humans; Lymphoma, B-Cell, Marginal Zo

2008

Other Studies

8 other studies available for mitoxantrone and Lymphoma, B-Cell, Marginal Zone

ArticleYear
Fludarabine-Mitoxantrone-Rituximab regimen in untreated indolent non-follicular non-Hodgkin's lymphoma: experience on 143 patients.
    Hematological oncology, 2015, Volume: 33, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Surviva

2015
Extranodal marginal zone B-cell lymphoma of the lung: experience with fludarabine and mitoxantrone-containing regimens.
    Hematological oncology, 2013, Volume: 31, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Disease-Free S

2013
Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) with mitoxantrone, chlorambucil and prednisone (MCP).
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:12

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Dis

2003
Multiple bilateral parotid sialoliths in a patient with mucosa-associated lymphoid tissue lymphoma (MALT lymphoma) of the salivary glands.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2005, Volume: 99, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dexamethasone; Doxorubicin; Female

2005
Routine application of the proton-pump inhibitor pantoprazole in patients with gastric lymphoma undergoing chemotherapy.
    Scandinavian journal of gastroenterology, 2005, Volume: 40, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-

2005
Activity of rituximab plus cyclophosphamide, doxorubicin/mitoxantrone, vincristine and prednisone in patients with relapsed MALT lymphoma.
    Oncology, 2006, Volume: 70, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Anti

2006
[MALT (mucosa-associated lymphoid tissue) lymphoma of the lacrimal gland].
    Journal francais d'ophtalmologie, 2007, Volume: 30, Issue:9

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemot

2007
[A clinical observation of fludarabine-containing regimens in the treatment of low grade non-Hodgkin's lymphoma].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2007, Volume: 29, Issue:9

    Topics: Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dexa

2007