mitoxantrone has been researched along with Leukoencephalopathy, Progressive Multifocal in 2 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
Leukoencephalopathy, Progressive Multifocal: An opportunistic viral infection of the central nervous system associated with conditions that impair cell-mediated immunity (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME and other IMMUNOLOGIC DEFICIENCY SYNDROMES; HEMATOLOGIC NEOPLASMS; IMMUNOSUPPRESSION; and COLLAGEN DISEASES). The causative organism is JC Polyomavirus (JC VIRUS) which primarily affects oligodendrocytes, resulting in multiple areas of demyelination. Clinical manifestations include DEMENTIA; ATAXIA; visual disturbances; and other focal neurologic deficits, generally progressing to a vegetative state within 6 months. (From Joynt, Clinical Neurology, 1996, Ch26, pp36-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report here a Japanese female with follicular lymphoma who subsequently developed PML." | 1.31 | Detection of human herpesvirus 6 and JC virus in progressive multifocal leukoencephalopathy complicating follicular lymphoma. ( Daibata, M; Hatakeyama, N; Hiroi, M; Kamioka, M; Miyoshi, I; Nemoto, Y; Taguchi, H, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vermersch, P | 1 |
| Kappos, L | 1 |
| Gold, R | 1 |
| Foley, JF | 1 |
| Olsson, T | 1 |
| Cadavid, D | 1 |
| Bozic, C | 1 |
| Richman, S | 1 |
| Daibata, M | 1 |
| Hatakeyama, N | 1 |
| Kamioka, M | 1 |
| Nemoto, Y | 1 |
| Hiroi, M | 1 |
| Miyoshi, I | 1 |
| Taguchi, H | 1 |
2 other studies available for mitoxantrone and Leukoencephalopathy, Progressive Multifocal
| Article | Year |
|---|---|
Clinical outcomes of natalizumab-associated progressive multifocal leukoencephalopathy.
Topics: Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineop | 2011 |
Detection of human herpesvirus 6 and JC virus in progressive multifocal leukoencephalopathy complicating follicular lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain; Cyclophosphamide; DNA, Vira | 2001 |