mitoxantrone has been researched along with Leukemia, Pre-B-Cell in 8 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report the development of therapy-related early pre-B acute lymphoblastic leukemia in a patient administered a topoisomerase II inhibitor, etoposide, a consolidation therapy agent for acute promyelocytic leukemia." | 3.72 | MLL/AF-1p fusion in therapy-related early pre-B acute lymphoblastic leukemia with t(1;11)(p32;q23) translocation developing in the relapse phase of acute promyelocytic leukemia. ( Kondo, T; Mikami, M; Nakanishi, H; Otsuki, T; Suemori, S; Suetsugu, Y; Sugihara, T; Tsujioka, T; Wada, H; Yamamori, S, 2003) |
| " Clofarabine dosed at 52 mg/m2 was used in adult patients with refractory ALL to maximize response before allo-HSCT." | 2.45 | The use of higher dose clofarabine in adults with relapsed acute lymphoblastic leukemia. ( Brown, AW; McGregor, BA; Osswald, MB; Savona, MR, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Parker, C | 1 |
| Krishnan, S | 1 |
| Hamadeh, L | 1 |
| Irving, JAE | 1 |
| Kuiper, RP | 1 |
| Révész, T | 1 |
| Hoogerbrugge, P | 1 |
| Hancock, J | 1 |
| Sutton, R | 1 |
| Moorman, AV | 1 |
| Saha, V | 1 |
| Rashed, WM | 1 |
| Zekri, W | 1 |
| Awad, M | 1 |
| Taha, H | 1 |
| Abdalla, B | 1 |
| Alfaar, AS | 1 |
| McGregor, BA | 1 |
| Brown, AW | 1 |
| Osswald, MB | 1 |
| Savona, MR | 1 |
| Wernstedt, P | 1 |
| Brune, M | 1 |
| Andersson, PO | 1 |
| Gustavsson, B | 1 |
| Stockelberg, D | 1 |
| Wadenvik, H | 1 |
| Tsujioka, T | 1 |
| Wada, H | 1 |
| Yamamori, S | 1 |
| Otsuki, T | 1 |
| Suemori, S | 1 |
| Kondo, T | 1 |
| Nakanishi, H | 1 |
| Suetsugu, Y | 1 |
| Mikami, M | 1 |
| Sugihara, T | 1 |
| Weide, R | 1 |
| Pandorf, A | 1 |
| Heymanns, J | 1 |
| Köppler, H | 1 |
| Kuga, T | 1 |
| Kohda, K | 1 |
| Hirayama, Y | 1 |
| Matsumoto, S | 1 |
| Nakazawa, O | 1 |
| Ando, M | 1 |
| Ezoe, A | 1 |
| Nobuoka, A | 1 |
| Mochizuki, C | 1 |
| Styczynski, J | 1 |
| Pieters, R | 1 |
| Huismans, DR | 1 |
| Schuurhuis, GJ | 1 |
| Wysocki, M | 1 |
| Veerman, AJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| ALLR3: An International Collaborative Trial for Relapsed and Refractory Acute Lymphoblastic Leukaemia (ALL)[NCT00967057] | Phase 3 | 470 participants (Anticipated) | Interventional | 2002-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for mitoxantrone and Leukemia, Pre-B-Cell
| Article | Year |
|---|---|
The use of higher dose clofarabine in adults with relapsed acute lymphoblastic leukemia.
Topics: Adenine Nucleotides; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Pr | 2009 |
2 trials available for mitoxantrone and Leukemia, Pre-B-Cell
| Article | Year |
|---|---|
Outcomes of patients with childhood B-cell precursor acute lymphoblastic leukaemia with late bone marrow relapses: long-term follow-up of the ALLR3 open-label randomised trial.
Topics: Adolescent; Bone Marrow; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Idarubicin; Inf | 2019 |
Bendamustine/Mitoxantrone/Rituximab (BMR): a very effective, well tolerated outpatient chemoimmunotherapy for relapsed and refractory CD20-positive indolent malignancies. Final results of a pilot study.
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, C | 2004 |
5 other studies available for mitoxantrone and Leukemia, Pre-B-Cell
| Article | Year |
|---|---|
Nonfunctioning Adrenocortical Carcinoma in Pediatric Acute Lymphoblastic Leukemia: A Case Report of a Rare Multiple Primaries Combination.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; | 2017 |
Favorable outcome with STI571 (imatinib mesylate) and allogeneic stem cell transplantation in a case of Ph+ chemorefractory acute lymphocytic leukaemia.
Topics: Adult; Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; | 2002 |
MLL/AF-1p fusion in therapy-related early pre-B acute lymphoblastic leukemia with t(1;11)(p32;q23) translocation developing in the relapse phase of acute promyelocytic leukemia.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Huma | 2003 |
Pulmonary veno-occlusive disease accompanied by microangiopathic hemolytic anemia 1 year after a second bone marrow transplantation for acute lymphoblastic leukemia.
Topics: Adolescent; Adrenal Cortex Hormones; Anemia, Hemolytic; Anti-Infective Agents; Antineoplastic Combin | 1996 |
In vitro drug resistance profiles of adult versus childhood acute lymphoblastic leukaemia.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents; Asparaginase; Bone Marrow Cells; Child; Child | 2000 |