mitoxantrone has been researched along with Leukemia, Myelomonocytic, Acute in 30 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
Leukemia, Myelomonocytic, Acute: A pediatric acute myeloid leukemia involving both myeloid and monocytoid precursors. At least 20% of non-erythroid cells are of monocytic origin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The incidence of secondary myelodysplasia/acute myeloid leukemia (AML) was retrospectively assessed in an international joint study in 305 node-positive breast cancer patients, who received mitoxantrone-based high-dose chemotherapy (HDCT) followed by autologous stem cell support as adjuvant therapy." | 8.82 | Secondary acute leukemia following mitoxantrone-based high-dose chemotherapy for primary breast cancer patients. ( Damon, L; Demirer, T; Derigs, G; Ferrante, P; Kröger, N; Rosti, G; Wandt, H; Zander, AR, 2003) |
| "The incidence of secondary myelodysplasia/acute myeloid leukemia (AML) was retrospectively assessed in an international joint study in 305 node-positive breast cancer patients, who received mitoxantrone-based high-dose chemotherapy (HDCT) followed by autologous stem cell support as adjuvant therapy." | 4.82 | Secondary acute leukemia following mitoxantrone-based high-dose chemotherapy for primary breast cancer patients. ( Damon, L; Demirer, T; Derigs, G; Ferrante, P; Kröger, N; Rosti, G; Wandt, H; Zander, AR, 2003) |
| "Of 40 patients with AML M3 or M3 v complete remission was attained in 62." | 2.67 | Clinical aspects of acute myeloid leukemias of the FAB types M3 and M4Eo. The AML Cooperative Group. ( Becher, R; Fonatsch, C; Gassmann, W; Haase, D; Haferlach, T; Jürgensen, C; Löffler, H; Ludwig, WD; Noak, J; Thiel, E, 1993) |
| "In the following study, patients with acute myeloid leukemia (AML) treated with double induction and consolidation chemotherapy (AML COOP study 1986, [3]) were randomized in a group with and without accompanying low-dose oral verapamil treatment." | 2.67 | Effects of verapamil on anthracycline-induced cardiomyopathy: preliminary results of a prospective multicenter trial. ( Appelt, M; Büchner, T; Eichelbaum, M; Grille, W; Hiddemann, W; Hossfeld, DK; Koslowski, B; Kraft, J; Kuse, R; Quabeck, K, 1990) |
| "From 1998 to 2001, 5 consecutive cases of AML/TMDS entered our hospital and achieved complete remission (CR) with continuous drip infusion of low-dose etoposide and low-dose Ara-C combined with mitoxantrone (MEtA regimen)." | 1.32 | [Five cases of de novo acute myeloid leukemia with trilineage myelodysplasia (AML/TMDS) achieved CR with the continuous drip infusion of low-dose etoposide and low-dose cytosine arabinoside combined with mitoxantrone (MEtA)]. ( Furukawa, Y; Kitani, T; Shibano, M; Tsukaguchi, M, 2004) |
| "A 47-year-old woman was diagnosed with acute myelomonocytic leukemia (AMMoL) and was treated with combination chemotherapy." | 1.29 | Hemolytic uremic syndrome developing during remission of acute myelomonocytic leukemia. ( Kobayashi, K; Kyohda, K; Matano, S; Matsuda, T; Nakamura, S; Ohtake, S; Okabe, Y; Okumura, H; Yoshida, T, 1993) |
| "We report a patient with acute myelomonocytic leukemia (AMMoL) who showed two independent point mutations of the N-ras gene at codons 12 and 13." | 1.29 | Double mutations of the N-ras gene in a patient with acute myelomonocytic leukemia. ( Hirakawa, K; Horiike, S; Kaneko, H; Kashima, K; Misawa, S; Nakai, H; Nakao, M; Taniwaki, M; Ueda, Y, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.33) | 18.7374 |
| 1990's | 19 (63.33) | 18.2507 |
| 2000's | 7 (23.33) | 29.6817 |
| 2010's | 3 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jaime-Pérez, JC | 1 |
| Brito-Ramirez, AS | 1 |
| Pinzon-Uresti, MA | 1 |
| Gutiérrez-Aguirre, H | 1 |
| Cantú-Rodríguez, OG | 1 |
| Herrera-Garza, JL | 1 |
| Gomez-Almaguer, D | 1 |
| Romani, C | 1 |
| Di Tucci, AA | 1 |
| Dessalvi, P | 1 |
| Pettinau, M | 1 |
| Emanuele, A | 1 |
| Cho, SF | 1 |
| Liu, TC | 1 |
| Chang, CS | 1 |
| Benasayag, S | 1 |
| Arias, E | 1 |
| Baialardo, E | 1 |
| Reyes, M | 1 |
| Sapia, S | 1 |
| Bistmans, A | 1 |
| Slavutsky, I | 1 |
| Delaunay, J | 1 |
| Vey, N | 1 |
| Leblanc, T | 1 |
| Fenaux, P | 1 |
| Rigal-Huguet, F | 1 |
| Witz, F | 1 |
| Lamy, T | 1 |
| Auvrignon, A | 1 |
| Blaise, D | 1 |
| Pigneux, A | 1 |
| Mugneret, F | 1 |
| Bastard, C | 1 |
| Dastugue, N | 1 |
| Van den Akker, J | 1 |
| Fière, D | 1 |
| Reiffers, J | 1 |
| Castaigne, S | 1 |
| Leverger, G | 1 |
| Harousseau, JL | 1 |
| Dombret, H | 1 |
| Kröger, N | 1 |
| Damon, L | 1 |
| Zander, AR | 1 |
| Wandt, H | 1 |
| Derigs, G | 1 |
| Ferrante, P | 1 |
| Demirer, T | 1 |
| Rosti, G | 1 |
| Tsukaguchi, M | 1 |
| Furukawa, Y | 1 |
| Shibano, M | 1 |
| Kitani, T | 1 |
| Tanasescu, R | 1 |
| Debouverie, M | 1 |
| Pittion, S | 1 |
| Anxionnat, R | 1 |
| Vespignani, H | 1 |
| Todisco, E | 1 |
| Testi, AM | 1 |
| Avvisati, G | 1 |
| Moleti, ML | 2 |
| Cedrone, M | 1 |
| Cimino, G | 1 |
| Mancini, F | 1 |
| Amadori, S | 3 |
| Mandelli, F | 2 |
| Okumura, H | 1 |
| Nakamura, S | 1 |
| Ohtake, S | 1 |
| Yoshida, T | 1 |
| Kobayashi, K | 1 |
| Okabe, Y | 1 |
| Matano, S | 1 |
| Kyohda, K | 1 |
| Matsuda, T | 1 |
| Haferlach, T | 1 |
| Gassmann, W | 1 |
| Löffler, H | 1 |
| Jürgensen, C | 1 |
| Noak, J | 1 |
| Ludwig, WD | 2 |
| Thiel, E | 1 |
| Haase, D | 1 |
| Fonatsch, C | 1 |
| Becher, R | 1 |
| Horiike, S | 1 |
| Misawa, S | 1 |
| Kaneko, H | 1 |
| Nakai, H | 1 |
| Ueda, Y | 1 |
| Nakao, M | 1 |
| Hirakawa, K | 1 |
| Taniwaki, M | 1 |
| Kashima, K | 1 |
| Visani, G | 1 |
| Petti, MC | 2 |
| Cenacchi, A | 1 |
| Manfroi, S | 1 |
| Tosi, P | 1 |
| Spadea, A | 1 |
| Latagliata, R | 1 |
| Tura, S | 1 |
| Wei, CH | 1 |
| Yu, IT | 1 |
| Tzeng, CH | 1 |
| Fan, FS | 1 |
| Hsieh, RK | 1 |
| Chiou, TJ | 1 |
| Liu, JH | 1 |
| Chen, PM | 1 |
| Salutari, P | 1 |
| Micciulli, G | 1 |
| Chiusolo, P | 1 |
| Tommasi, M | 1 |
| Di Mario, A | 1 |
| Sica, S | 1 |
| Leone, G | 1 |
| Okamoto, M | 1 |
| Miyazaki, H | 1 |
| Tsuzuki, M | 1 |
| Ino, T | 1 |
| Ezaki, K | 1 |
| Hirano, M | 1 |
| Vignetti, M | 1 |
| Orsini, E | 1 |
| Andrizzi, C | 1 |
| Pinto, RM | 1 |
| Meloni, G | 1 |
| Tzavara, V | 1 |
| Stamoulis, K | 1 |
| Aroni, KG | 1 |
| Kordossis, T | 1 |
| Boki, KA | 1 |
| Wahlin, A | 1 |
| Brinch, L | 1 |
| Hörnsten, P | 1 |
| Evensen, SA | 1 |
| Oberg, G | 1 |
| Simonsson, B | 1 |
| Hedenus, M | 1 |
| Pavlovsky, S | 1 |
| Fernández, I | 1 |
| Milone, G | 1 |
| Martinez Rolón, J | 1 |
| Corrado, C | 1 |
| Desmery, P | 1 |
| Dignani, C | 1 |
| Michelet, M | 1 |
| Juni, M | 1 |
| Orlandi, E | 1 |
| Lazzarino, M | 1 |
| Bernasconi, P | 1 |
| Astori, C | 1 |
| Bernasconi, C | 2 |
| Ghosh, K | 1 |
| Mitra, S | 1 |
| Hiwase, D | 1 |
| Nørgaard, JM | 1 |
| Olesen, LH | 1 |
| Olesen, G | 1 |
| Meyer, K | 1 |
| Kristensen, JS | 1 |
| Bendix, K | 1 |
| Pedersen, B | 1 |
| Kjeldsen, E | 1 |
| Hokland, P | 1 |
| Ehninger, G | 1 |
| Fackler-Schwalbe, E | 1 |
| Freund, M | 1 |
| Heil, G | 1 |
| Henke, M | 1 |
| Hoelzer, D | 1 |
| Hoffmann, R | 1 |
| Kurrle, E | 1 |
| Link, H | 1 |
| Lösch, A | 1 |
| Rowe, JM | 1 |
| Mazza, JJ | 1 |
| Hines, JD | 1 |
| Cassileth, PA | 1 |
| Oken, MM | 1 |
| Bennett, JM | 1 |
| Andersen, J | 1 |
| Kraft, J | 1 |
| Grille, W | 1 |
| Appelt, M | 1 |
| Hossfeld, DK | 1 |
| Eichelbaum, M | 1 |
| Koslowski, B | 1 |
| Quabeck, K | 1 |
| Kuse, R | 1 |
| Büchner, T | 2 |
| Hiddemann, W | 3 |
| Aul, HC | 1 |
| Maschmeyer, G | 1 |
| Urbanitz, D | 1 |
| Lathan, B | 1 |
| Reichle, A | 1 |
| Köppler, H | 1 |
| Donhuijsen-Ant, R | 1 |
| Grüneisen, T | 1 |
| Kajigaya, Y | 1 |
| Takahashi, H | 1 |
| Sekiguchi, H | 1 |
| Okuyama, T | 1 |
| Ikuta, K | 1 |
| Sasaki, H | 1 |
| Kanaya, A | 1 |
| Matsuyama, S | 1 |
| Essink, ME | 1 |
| von Eiff, M | 1 |
| van de Loo, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 2 Study of Autologous Hematopoietic Cell Transplantation for Core-binding Factor Positive Acute Myeloid Leukemia in the First Complete Remission[NCT01050036] | 39 participants (Anticipated) | Interventional | 2010-01-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for mitoxantrone and Leukemia, Myelomonocytic, Acute
| Article | Year |
|---|---|
Prognosis of inv(16)/t(16;16) acute myeloid leukemia (AML): a survey of 110 cases from the French AML Intergroup.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromoso | 2003 |
Secondary acute leukemia following mitoxantrone-based high-dose chemotherapy for primary breast cancer patients.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantat | 2003 |
Etoposide: fifteen years experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Hodgkin Dise | 1989 |
9 trials available for mitoxantrone and Leukemia, Myelomonocytic, Acute
| Article | Year |
|---|---|
Clinical aspects of acute myeloid leukemias of the FAB types M3 and M4Eo. The AML Cooperative Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Cytarabine; Daunorubicin; Humans; Le | 1993 |
MEC (mitoxantrone, etoposide and intermediate dose cytarabine): an effective induction regimen for previously untreated acute non-lymphocytic leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Drug | 1995 |
Probability of long-term disease-free survival for acute myeloid leukemia patients after first relapse: A single-centre experience.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation | 1996 |
Outcome of a multicenter treatment program including autologous or allogeneic bone marrow transplantation for de novo acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Amsacrine; Antineoplastic Combined Chemotherapy Proto | 1997 |
Autologous peripheral blood progenitor cell transplantation mobilized with high-dose cytarabine in acute myeloid leukemia in first complete remission.
Topics: Adolescent; Adult; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purgi | 1998 |
Combination of mitoxantrone and etoposide in patients aged over 60 years with untreated acute myelogenous leukemia.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Etoposide; Humans; Leuke | 1990 |
Mitoxantrone and etoposide in patients with relapsed and refractory acute nonlymphocytic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Etoposide; Humans; Leukemia, | 1990 |
Effects of verapamil on anthracycline-induced cardiomyopathy: preliminary results of a prospective multicenter trial.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathies; Cytarabine; Dau | 1990 |
Proposal for the classification of relapsed and refractory acute myeloid leukemias as the basis for an age-adjusted randomized comparison of sequentially applied high-dose versus intermediate-dose cytosine arabinoside in combination with mitoxantrone (S-H
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Austria; Child | 1990 |
18 other studies available for mitoxantrone and Leukemia, Myelomonocytic, Acute
| Article | Year |
|---|---|
Characteristics and clinical evolution of patients with acute myeloblastic leukemia in northeast Mexico: an eight-year experience at a university hospital.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antineoplastic Combined Chemother | 2014 |
Intrathecal chemotherapy and meningeal relapses in myelomonocytic AML. A single institution experience.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modalit | 2010 |
Isolated central nervous system relapse presenting as myeloid sarcoma of acute myeloid leukemia after allogeneic peripheral blood stem cell transplantation.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellopontine Angle; Combined Modality The | 2013 |
Inv(4)(p14q27) in a case with de novo acute nonlymphocytic leukemia.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosome Inversion; Chromosomes | 2002 |
[Five cases of de novo acute myeloid leukemia with trilineage myelodysplasia (AML/TMDS) achieved CR with the continuous drip infusion of low-dose etoposide and low-dose cytosine arabinoside combined with mitoxantrone (MEtA)].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cell Lineage; Cytarabine; Disease-Free Surviv | 2004 |
Acute myeloid leukaemia induced by mitoxantrone in a multiple sclerosis patient.
Topics: Adult; Antineoplastic Agents; Humans; Leukemia, Myelomonocytic, Acute; Male; Mitoxantrone; Multiple | 2004 |
Therapy-related acute myelomonocytic leukemia following successful treatment for acute promyelocytic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 10; Chromosomes | 1995 |
Hemolytic uremic syndrome developing during remission of acute myelomonocytic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Hemolyt | 1993 |
Double mutations of the N-ras gene in a patient with acute myelomonocytic leukemia.
Topics: Aclarubicin; Alleles; Antineoplastic Combined Chemotherapy Protocols; Chromosome Deletion; Chromosom | 1995 |
Trisomy 21 in acute myeloid leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Down Syndrome; Humans; Hydroxyure | 1996 |
Late relapse after autologous BMT.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Cyclophospham | 1996 |
[Long-term selective beta 1-blockade therapy for a patient with anthracycline-induced cardiomyopathy].
Topics: Aclarubicin; Adrenergic beta-Antagonists; Adult; Antibiotics, Antineoplastic; Cardiomyopathy, Hypert | 1995 |
Facial heliotrope rash as the initial manifestation of acute myelomonocytic leukemia.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arthritis; Bo | 1997 |
Secondary acute myeloid leukemia following treatment with VP16-containing regimens for non-Hodgkin's lymphoma.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bleo | 1998 |
Choroidal infiltrates simulating fundal changes of acute leukemia during hematological recovery following high-dose chemotherapy in acute myelomonocytic leukemia in remission.
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cerebrospinal Flu | 2000 |
FAB M4 and high CD14 surface expression is associated with high cellular resistance to Ara-C and daunorubicin: implications for clinical outcome in acute myeloid leukaemia.
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antigens, Neoplas | 2001 |
[Induction of differentiation of myelomonocytic leukemia cells by mitoxantrone].
Topics: Adolescent; Cell Differentiation; Cell Division; Child; Child, Preschool; Humans; Infant; Leukemia, | 1990 |
Effect of antifungal therapy on hematological recovery after intensive antileukemic chemotherapy.
Topics: Agranulocytosis; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daun | 1990 |