mitoxantrone has been researched along with Leiomyosarcoma in 3 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
Leiomyosarcoma: A sarcoma containing large spindle cells of smooth muscle. Although it rarely occurs in soft tissue, it is common in the viscera. It is the most common soft tissue sarcoma of the gastrointestinal tract and uterus. The median age of patients is 60 years. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1865)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-nine evaluable patients with metastatic or recurrent leiomyosarcoma or malignant mixed mesodermal tumors of the uterus were treated with mitoxantrone 12 mg/m2 every 3 weeks." | 5.06 | Mitoxantrone in the treatment of advanced uterine sarcoma. A phase II trial of the Gynecologic Oncology Group. ( Adcock, L; Beecham, J; Bundy, BN; Muss, HB, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Görich, J | 1 |
| Brensing, KA | 1 |
| Kunze, V | 1 |
| Sokiranski, R | 1 |
| Rilinger, N | 1 |
| Müller-Miny, H | 1 |
| Brambs, HJ | 1 |
| Saglik, Y | 1 |
| Icli, F | 1 |
| Uluoglu, O | 1 |
| Isiklar, ZU | 1 |
| Muss, HB | 1 |
| Bundy, BN | 1 |
| Adcock, L | 1 |
| Beecham, J | 1 |
1 trial available for mitoxantrone and Leiomyosarcoma
| Article | Year |
|---|---|
Mitoxantrone in the treatment of advanced uterine sarcoma. A phase II trial of the Gynecologic Oncology Group.
Topics: Adult; Aged; Drug Evaluation; Female; Humans; Leiomyosarcoma; Middle Aged; Mitoxantrone; Multicenter | 1990 |
2 other studies available for mitoxantrone and Leiomyosarcoma
| Article | Year |
|---|---|
[Percutaneous drainage of refractory necrotizing tumors: experience in 9 patients].
Topics: Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Cystadenocarcinoma; Drainage; Female; His | 1995 |
Leiomyosarcoma of the great saphenous vein.
Topics: Combined Modality Therapy; Female; Humans; Leiomyosarcoma; Lung Neoplasms; Middle Aged; Mitoxantrone | 1992 |