Page last updated: 2024-10-31

mitoxantrone and Diffuse Mixed Small and Large Cell Lymphoma

mitoxantrone has been researched along with Diffuse Mixed Small and Large Cell Lymphoma in 220 studies

Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.

Research Excerpts

ExcerptRelevanceReference
"We have studied the plasma and peripheral leukocyte pharmacokinetics of mitoxantrone associated, in a high-dose regimen, with cyclophosphamide, carmustine, and etoposide in patients with refractory lymphoma undergoing autologous bone marrow transplantation."9.07Plasma and cellular pharmacokinetics of mitoxantrone in high-dose chemotherapeutic regimen for refractory lymphomas. ( Attal, M; Bugat, R; Canal, P; Chatelut, E; Guichard, S; Houin, G; Huguet, F; Laurent, G; Muller, C; Schlaifer, D, 1993)
"Prior studies of the combination of fludarabine, mitoxantrone and dexamethasone have yielded high response rates but are associated with a significant risk of opportunistic infections, predominantly Pneumocystis Carinii pneumonia (PCP) requiring routine prophylaxis."5.09Fludarabine and mitoxantrone: effective and well-tolerated salvage therapy in relapsed indolent lymphoproliferative disorders. ( Fox, RM; Grigg, AP; Seymour, JF; Szer, J, 2001)
" Three cohorts of ten patients with breast cancer (BC) or non-Hodgkin's lymphoma (NHL) received escalating doses of NOV, 60, 75 and 90 mg m(-2) plus melphalan (L-PAM), 140-180 mg m(-2), with PBPC rescue 96 h after NOV."5.08High-dose mitoxantrone with peripheral blood progenitor cell rescue: toxicity, pharmacokinetics and implications for dosage and schedule. ( Ballestrero, A; Basta, P; Brema, F; Esposito, M; Ferrando, F; Friedman, D; Garuti, A; Gonella, R; Mela, GS; Patrone, F; Puglisi, M; Sessarego, M; Sorice, G; Vannozzi, MO, 1997)
"We have studied the plasma and peripheral leukocyte pharmacokinetics of mitoxantrone associated, in a high-dose regimen, with cyclophosphamide, carmustine, and etoposide in patients with refractory lymphoma undergoing autologous bone marrow transplantation."5.07Plasma and cellular pharmacokinetics of mitoxantrone in high-dose chemotherapeutic regimen for refractory lymphomas. ( Attal, M; Bugat, R; Canal, P; Chatelut, E; Guichard, S; Houin, G; Huguet, F; Laurent, G; Muller, C; Schlaifer, D, 1993)
" Fifty-five breast cancer patients treated with mitoxantrone, methotrexate and 5-fluorouracil gave a response rate of 52."5.06[Mitoxantrone containing multi-drug chemotherapy in the management of malignancies. Collaborative Group for Clinical Trial of Mitoxantrone]. ( , 1989)
" Patients who proceeded to haematopoietic stem cell transplants (HDTs) received conditioning therapy with BEAM [for the Hodgkin's Lymphoma (HL) and non-Hodgkin's Lymphoma (NHL) groups], or melphalan 100 mg/m2 and mitoxantrone [for the multiple myeloma (MM) patients]."3.73Ifosfamide, epirubicin, etoposide (IEV) and autologous peripheral blood progenitor cell transplant: a feasible and effective salvage treatment for lymphoid malignancies. ( Albarello, A; Ballerini, F; Balocco, M; Canepa, L; Canepa, P; Clavio, M; Garrone, A; Gobbi, M; Michelis, GL; Miglino, M; Pierri, I; Varaldo, R, 2005)
"Nineteen patients with metastatic breast cancer and six patients with refractory non-Hodgkin's lymphoma were initially treated with etoposide (VP-16) (2 gm/m2) and granulocyte-colony stimulating factor (G-CSF)."3.69Multiple cycles of high dose chemotherapy supported by hematopoietic progenitor cells as treatment for patients with advanced malignancies. ( Blume, KG; Chao, NJ; Hoyle, CF; Kusnierz-Glaz, CR; Long, GD; Negrin, RS; Schriber, JR, 1995)
"Follicular lymphoma is the most common form of lymphoma in Europe and the USA."2.73Fludarabine and mitoxantrone followed by yttrium-90 ibritumomab tiuxetan in previously untreated patients with follicular non-Hodgkin lymphoma trial: a phase II non-randomised trial (FLUMIZ). ( Baccarani, M; Cabras, MG; De Luca, S; De Renzo, A; Derenzini, E; Fabbri, A; Fanti, S; Fattori, P; Fina, M; Gobbi, M; Guardigni, L; Marchi, E; Musuraca, G; Pellegrini, C; Perotti, A; Piccaluga, PP; Pileri, S; Pulsoni, A; Rigacci, L; Ronconi, S; Stefoni, V; Tani, M; Voso, MT; Zaccaria, A; Zinzani, PL, 2008)
"Rituximab, a chimeric monoclonal antibody, produces response rates of up to 73% in patients with previously untreated indolent non-Hodgkin's lymphoma (NHL), and has high activity when combined with chemotherapy."2.71Rituximab in combination with CNOP chemotherapy in patients with previously untreated indolent non-Hodgkin's lymphoma. ( Christodoulou, C; Dimopoulos, M; Economopoulos, T; Fountzilas, G; Hamilos, G; Kalantzis, D; Nicolaides, C; Papageorgiou, E; Pavlidis, N, 2003)
"Two cases of acute myelogenous leukemia (AML) were recorded, both in the iCNOP arm (p = 0."2.71A randomized trial comparing intensified CNOP vs. CHOP in patients with aggressive non-Hodgkin's lymphoma. ( Angelopoulou, MK; Bourantas, KL; Christopoulos, G; Grigorakis, V; Kalmantis, T; Kokkinis, G; Korantzis, J; Michalis, E; Mihalakeas, I; Pangalis, GA; Papayiannis, A; Repousis, P; Roussou, P; Siakantaris, MP; Stamatellou, M; Stefanoudakis, E; Symeonidis, A; Vassilakopoulos, TP; Vrakidou, E, 2003)
"Acute renal failure and bacterial infection occurred as non-hematologic dose limiting toxicities."2.70A dose escalation study for salvage chemotherapy in patients with refractory lymphoma prior to high-dose myeloablative therapy with stem cell transplantation. ( de Magalhaes-Silverman, M; Gingrich, RD; Hayashi, M; Hohl, RJ; Lee, CK; Schlueter, A; Strauss, RG, 2002)
" No toxic deaths have occurred."2.69Etoposide, mitoxantrone and prednisone: a salvage regimen with low toxicity for refractory or relapsed non-Hodgkin's lymphoma. ( Budel, L; Doorduijn, JK; Löwenberg, B; Sonneveld, P; Spruit, P; van Der Holt, B; van't Veer, M, 2000)
"Evaluate response, duration of response, and toxicity of paclitaxel in combination with other drugs known to be effective in non-Hodgkin's lymphoma (NHL)."2.69Phase II study of paclitaxel in combination with mitoxantrone and ifosfamide/mesna for patients with relapsed or refractory non-Hodgkin's lymphoma after failure to cytarabine/cisplatin combination. ( Cabanillas, F; Hagemeister, FB; McLaughlin, P; Preti, A; Rodriguez, J; Rodriguez, MA; Romaguera, JE; Sarris, AH; Younes, A, 1999)
" The maximal acceptable dosage of mitoxantrone was 10 mg/m2 x 2 due to serious hematologic toxicity."2.69Mitoxantrone-DHAP with GM-CSF: an active but myelosuppressive salvage therapy for relapsed/refractory aggressive non-Hodgkin's lymphoma. ( Berinstein, NL; Franssen, E; Haq, R; Sawka, CA, 1999)
"Treatment of Hodgkin's disease (HD) and non-Hodgkin lymphomas (NHL) is still unsatisfactory in patients resistant to primary therapy or those with early relapses."2.69[Chemotherapy of resistant and recurrent lymphoma based on a combination of ifosfamide and etoposide. Antitumor effects, toxicity and stimulation of peripheral stem cells]. ( Adam, Z; Hájek, R; Hejlová, N; Klabusay, M; Korístek, Z; Krahulcová, E; Král, Z; Mayer, J; Müllerová, I; Navrátil, M; Penka, M; Tomíska, M; Vásová, I; Vodvárka, P; Vorlícek, J, 1998)
"Ara-C was administered at a dosage of 3 gm/sqm for 2-hour intravenous infusion every 12 hours from day 1 to day 4 (8 doses), and mitoxantrone was given at a dosage of 6 mg/sqm/day for 1-hour intravenous infusion from day 1 to day 5."2.68High-dose cytarabine and mitoxantrone as salvage therapy for refractory non-Hodgkin's lymphoma. ( Chen, PM; Chiou, TJ; Fan, S; Liu, JH; Tzeng, CH; Wang, WS, 1996)
" NO was applied at a dosage of 10 mg/m2/day on days 2 and 3 and AC at 3 g/m2/12h on days 1 and 2."2.67Mitoxantrone/high-dose Ara-C and recombinant human GM-CSF in the treatment of refractory non-Hodgkin's lymphoma. A pilot study. ( Andreesen, R; Del Valle, F; Engelhard, M; Fiedler, W; Haas, R; Hiddemann, W; Ho, AD; Rückle, H; Schlimok, G; Thiel, E, 1990)
"Objective response rates were 21% in breast cancer, 36% in non-Hodgkin's lymphoma, 56% in acute lymphocytic leukemia, 14% in acute nonlymphocytic leukemia, 31% in gastric cancer and 5% in primary hepatic cancer."2.66[Phase II clinical trial on mitoxantrone]. ( Gao, HR, 1989)
"Mitoxantrone is an effective agent in refractory NHL and should be taken into consideration in the design of salvage regimens."2.66Mitoxantrone: an active agent in refractory non-Hodgkin's lymphomas. ( Bajetta, E; Bonadonna, G; Buzzoni, R; Valagussa, P, 1988)
"Mitoxantrone has a broad anti-tumour activity including lymphoma with potentially less cardiotoxicity than doxorubicin, which may be of particular importance in elderly patients."2.44CNOP (mitoxantrone) chemotherapy is inferior to CHOP (doxorubicin) in the treatment of patients with aggressive non-Hodgkin lymphoma (meta-analysis). ( Ahlbom, A; Anders, A; Andersson, T; Björkholm, M; Eva, O; Magnus, B; Ösby, E; Tomas, A, 2008)
"Most patients with follicular lymphoma respond to therapy, and the average survival time in large series is approximately 10 years."2.42Treatment of indolent non-Hodgkin's lymphoma with cladribine as single-agent therapy and in combination with mitoxantrone. ( Armitage, JO; Hoelzer, D; Rummel, MJ; Tobinai, K, 2004)
"A 47 year old woman with a MALT lymphoma affecting the breast exclusively is reported."2.40[Primary MALT-type lymphoma of the breast]. ( Campo, E; Cervantes, F; Esteve, J; Montserrat, E; Rafel, M; Serra, A; Velasco, M, 1998)
"Histopathological subtypes consist of Burkitt's lymphoma (BL) in 32 (43."1.48Demographics and Outome in Paediatric Non-Hodgkin Lymphoma: Single Centre Experience at The Children Hospital Lahore, Pakistan. ( Anwar, S; Faizan, M; Khan, S, 2018)
"There were 32 small lymphocytic lymphomas and 111 marginal zone lymphomas."1.42Fludarabine-Mitoxantrone-Rituximab regimen in untreated indolent non-follicular non-Hodgkin's lymphoma: experience on 143 patients. ( Argnani, L; Broccoli, A; Casadei, B; Gandolfi, L; Maglie, R; Pellegrini, C; Pileri, S; Stefoni, V; Zinzani, PL, 2015)
" TMJ is a safe and effective regimen when used as a part of autologous stem cell transplant for patients with HD and NHL."1.32High dose chemotherapy with thiotepa, mitoxantrone and carboplatin (TMJ) followed by autologous stem cell support in 100 consecutive lymphoma patients in a single centre: analysis of efficacy, toxicity and prognostic factors. ( Ahmed, T; Hoang, A; Kancherla, R; Liu, D; Qureshi, Z; Seiter, K; Waheed, F, 2004)
"Seventeen patients had small lymphocytic lymphoma (SLL), 29 had follicular lymphoma (FL), 10 of them with histologic transformation."1.31Long-term follow-up of advanced-stage low-grade lymphoma patients treated upfront with high-dose sequential chemotherapy and autograft. ( Caracciolo, D; Corradini, P; Cuttica, A; Gavarotti, P; Ladetto, M; Novero, D; Pileri, A; Rossi, G; Tarella, C; Zallio, F, 2000)
"We describe two cases of interstitial lung disease in patients with non-Hodgkin's lymphoma who were treated with combination chemotherapy including mitozantrone."1.30Interstitial pneumonitis following mitozantrone, chlorambucil and prednisolone (MCP) chemotherapy. ( Johnson, S; Nicholson, AG; Rule, S; Stone, R; Tighe, M; Tomlinson, J, 1999)
"Mitoxantrone was dose-escalated in increments of 2."1.29Cladribine and mitoxantrone dose escalation in indolent non-Hodgkin's lymphoma. ( Kosty, M; Lee, T; Piro, L; Saven, A, 1996)
"Chylothorax is an accumulation of thoracic lymph or chyle in the pleural cavity."1.29Intrapleural bleomycin in the treatment of chylothorax. ( Aasebø, U; Norum, J, 1994)
"In stage III and IV Hodgkin's disease, for example, an age-adjusted COPP regimen may be adopted."1.28[Treatment of elderly patients with hematological malignancies]. ( Mizoguchi, H; Saito, H, 1992)
" In the second study (NOAC II), the dosage of cytarabine was escalated to 3 g/m2/12 h on days 1 and 2 (4 doses) while mitoxantrone remained 10 mg/m2/d on days 2 and 3."1.28Sequential studies on the role of mitoxantrone, high-dose cytarabine, and recombinant human granulocyte-macrophage colony-stimulating factor in the treatment of refractory non-Hodgkin's lymphoma. ( Andreesen, R; Del Valle, F; Engelhard, M; Fiedler, W; Haas, R; Hiddemann, W; Ho, AD; Rückle, H; Schlimok, G; Thiel, E, 1990)
"Myelosuppression with subsequent infections was the major toxicity of this regimen."1.28Mitoxantrone and high-dose cytarabine as salvage therapy for refractory non-Hodgkin's lymphoma. ( del Valle, F; Dörken, B; Hiddemann, W; Ho, AD; Hunstein, W; Meusers, P; Rückle, H; Schlimok, G; Schwammborn, J; Thiel, E, 1989)
"However, cardiac failure, the primary cause of death in four patients, was associated with coagulative fiber necroses and contraction band necroses, which may be related to acute cyclophosphamide toxicity."1.27Cardiac damage in autologous bone marrow transplant patients: an autopsy study. Cardiotoxic pretreatment as a major risk factor. ( Dörken, B; Körbling, M; Mall, G; von Herbay, A, 1988)
"One of 11 patients with Hodgkin's disease, 2 of 12 with favorable-histology non-Hodgkin's lymphoma, 4 of 27 with unfavorable-histology non-Hodgkin's lymphoma, and 1 of 11 with chronic lymphocytic leukemia showed a response."1.27Weekly mitoxantrone therapy of Hodgkin's disease, non-Hodgkin's lymphoma, and chronic lymphocytic leukemia. A Southeastern Cancer Study Group Trial. ( Bartolucci, AA; Gams, RA; Keller, JW; Omura, GA, 1987)

Research

Studies (220)

TimeframeStudies, this research(%)All Research%
pre-199014 (6.36)18.7374
1990's113 (51.36)18.2507
2000's85 (38.64)29.6817
2010's8 (3.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nastoupil, LJ1
McLaughlin, P11
Feng, L1
Neelapu, SS1
Samaniego, F1
Hagemeister, FB9
Ayala, A2
Romaguera, JE6
Goy, AH1
Neal, E1
Wang, M1
Fayad, L2
Fanale, MA1
Oki, Y1
Westin, JR1
Rodriguez, MA11
Cabanillas, F13
Fowler, NH1
Faizan, M1
Anwar, S1
Khan, S1
Marquardt, TM1
Lindley, SES1
Smith, AN1
Cannon, CM1
Rodriguez, CO1
Thamm, DH1
Childress, MO1
Northrup, NC1
Zinzani, PL10
Pellegrini, C3
Broccoli, A2
Gandolfi, L2
Stefoni, V6
Casadei, B1
Maglie, R1
Argnani, L2
Pileri, S2
Cohen, JB1
Bucur, S1
Winton, EF1
Sinha, R1
Heffner, LT1
King, N1
Lonial, S1
Langston, AA1
Waller, EK1
Hutchison-Rzepka, A1
Colbert, A1
Lechowicz, MJ1
Flowers, CR1
Zwick, C1
Birkmann, J2
Peter, N1
Bodenstein, H2
Fuchs, R1
Hänel, M2
Reiser, M1
Hensel, M1
Clemens, M1
Zeynalova, S1
Ziepert, M1
Pfreundschuh, M1
Jonathan, F1
Gobbi, PG1
Valentino, F1
Lambelet, P1
Perfetti, V1
Bergamaschi, G1
Girino, M1
Corazza, GR1
Sharma, R1
Cunningham, D3
Smith, P3
Robertson, G1
Dent, O1
Clarke, SJ1
Dincol, D2
Buyukcelik, A1
Dogan, M1
Akbulut, H2
Samur, M1
Demirkazik, A2
Senler, FC1
Onur, H1
Icli, F2
Fanti, S3
Derenzini, E3
Quirini, F1
Baccarani, M4
Monjanel, H1
Deconinck, E2
Perrodeau, E1
Gastinne, T1
Delwail, V3
Moreau, A1
François, S1
Berthou, C2
Gyan, E1
Milpied, N1
Schmitt, B1
Wendtner, CM1
Bergmann, M1
Busch, R1
Franke, A2
Pasold, R2
Schlag, R1
Hopfinger, G1
Hiddemann, W13
Emmerich, B1
Hallek, M1
Handa, H1
Motohashi, S1
Isozumi, K1
Komatsumoto, S1
Nara, M1
Vose, JM1
Weisenburger, DD1
Lynch, JC1
Bierman, PJ1
Chan, JC1
Bast, M1
Aoun, P1
Bociek, G1
Greiner, T1
Armitage, JO2
Rummel, MJ2
Chow, KU1
Karakas, T1
Jäger, E1
Mezger, J1
von Grünhagen, U1
Schalk, KP1
Burkhard, O1
Hansmann, ML1
Ritzel, H1
Bergmann, L1
Hoelzer, D2
Mitrou, PS1
Lee, CK1
de Magalhaes-Silverman, M1
Hayashi, M1
Schlueter, A1
Strauss, RG1
Hohl, RJ1
Gingrich, RD1
Gherlinzoni, F6
Storti, S3
Zaccaria, A3
Pavone, E3
Moretti, L3
Gentilini, P3
Guardigni, L4
De Renzo, A3
Fattori, PP3
Falini, B3
Lauta, VM3
Mannina, D1
Zaja, F2
Mazza, P3
Volpe, E2
Lauria, F1
Aitini, E3
Ciccone, F1
Tani, M3
Alinari, L1
Tura, S7
Büchler, T1
Ferra, C1
Virgili, N1
Montanya, E1
Grañena, A1
Tsimberidou, AM2
Younes, A4
Sarris, A2
Romaguera, J3
Hess, M2
Smith, TL1
Yang, Y1
Preti, A2
Lee, MS2
Forstpointner, R1
Hänel, A2
Repp, R1
Hermann, S1
Metzner, B1
Pott, C1
Hartmann, F1
Rothmann, F1
Böck, HP1
Wandt, H1
Unterhalt, M8
Gibson, AD1
Emmanouilides, C1
Lill, M1
Telatar, M1
Rosenfelt, F1
Grody, W1
Territo, M1
Rosen, P1
Bessell, EM2
Burton, A1
Haynes, AP1
Glaholm, J1
Child, JA1
Cullen, MH1
Davies, JM2
Smith, GM1
Ellis, IO2
Jack, A2
Jones, EL1
Herold, M1
Dölken, G1
Fiedler, F2
Freund, M4
Helbig, W1
Milone, G1
Di Raimondo, F1
Gioi, FL1
Palumbo, GA1
Manenti, GO1
Pafumi, M1
Giustolisi, R1
Dreyling, M2
Velasquez, WS1
Lew, D1
Grogan, TM1
Spiridonidis, CH1
Balcerzak, SP1
Dakhil, SR1
Miller, TP2
Lanier, KS1
Chapman, RA1
Fisher, RI2
Economopoulos, T4
Fountzilas, G4
Pavlidis, N2
Kalantzis, D1
Papageorgiou, E2
Christodoulou, C1
Hamilos, G1
Nicolaides, C3
Dimopoulos, M1
Pangalis, GA2
Vassilakopoulos, TP1
Michalis, E1
Roussou, P2
Vrakidou, E1
Repousis, P1
Angelopoulou, MK2
Siakantaris, MP1
Korantzis, J1
Symeonidis, A1
Grigorakis, V1
Stefanoudakis, E1
Stamatellou, M1
Bourantas, KL1
Kalmantis, T1
Christopoulos, G1
Kokkinis, G1
Mihalakeas, I1
Papayiannis, A1
Hainsworth, JD1
Litchy, S1
Lamb, MR1
Rodriguez, GI1
Scroggin, C1
Greco, FA1
Lyman, GH2
Delgado, DJ2
Mantzios, G2
Tsirigotis, P1
Veliou, F1
Boutsikakis, I1
Petraki, L1
Kolovos, J1
Papageorgiou, S2
Robos, Y1
Froehner, M1
Haase, M1
Hakenberg, OW1
Wirth, MP1
Ma, SY1
Au, WY1
Chim, CS1
Lie, AK1
Lam, CC1
Tse, E1
Leung, AY1
Liang, R1
Kwong, YL1
Bordonaro, R1
Petralia, G1
Restuccia, N1
Todaro, AM1
Serraino, D2
Giuffrida, D1
Cordio, S1
Giannitto-Giorgio, C1
Salice, P1
Ursino, M1
Novello, G1
Marletta, F1
Manusia, M1
Tobinai, K1
Osby, E3
Askling, J1
Landgren, O1
Dickman, PW1
Ekbom, A1
Björkholm, M3
Hendry, L1
Bowen, A1
Matutes, E1
Swansbury, J1
Catovsky, D1
Dale, DC1
Friedberg, J1
Crawford, J1
Waheed, F1
Kancherla, R2
Seiter, K2
Liu, D1
Qureshi, Z1
Hoang, A1
Ahmed, T1
Wöhrer, S1
Raderer, M1
Kaufmann, H1
Hejna, M1
Chott, A1
Zielinski, CC1
Drach, J1
Rigacci, L3
Carrai, V1
Nassi, L1
Alterini, R2
Longo, G2
Bernardi, F2
Bosi, A1
Di Bella, N1
Reynolds, C1
Faragher, D1
Muscato, J1
Boehm, KA1
Asmar, L1
Ishii, K1
Yamamoto, Y1
Shigeki, T1
Kitayama, H1
Hayashi, K3
Hirose, A1
Ohta, T1
Mugitani, A1
Fujino, H1
Yagi, T1
Hirai, M1
Teshima, H1
Katsurada, T1
Urase, F1
Kitajima, H1
Foussard, C2
Colombat, P1
Maisonneuve, H2
Gressin, R2
Rousselet, MC1
Rachieru, P1
Pignon, B1
Mahé, B1
Ghandour, C1
Desablens, B1
Casassus, P1
Lamy, T1
Gershanovich, ML1
Tikhonova, VV1
van Imhoff, GW1
van der Holt, B2
Mackenzie, MA1
Van't Veer, MB1
Wijermans, PW2
Ossenkoppele, GJ1
Schouten, HC2
Sonneveld, P6
Steijaert, MM1
Kluin, PM1
Kluin-Nelemans, HC1
Verdonck, LF1
Chamorey, E1
Peyrade, F1
Rossi, JF1
Lepeu, G1
Harrousseau, JL1
Fabbro, M1
Richard, B1
Vilque, JP1
Thyss, A1
Clavio, M2
Garrone, A1
Pierri, I1
Michelis, GL1
Balocco, M1
Albarello, A1
Varaldo, R1
Canepa, P1
Miglino, M1
Ballerini, F1
Canepa, L1
Gobbi, M6
Enschede, SH1
Porter, C1
Venugopal, P1
Gregory, SA2
Sorá, F1
Piccirillo, N1
Chiusolo, P1
Laurenti, L1
Marra, R1
Bartolozzi, F1
Leone, G3
Sica, S1
Burton, C1
Linch, D2
Hoskin, P2
Milligan, D1
Dyer, MJ1
Hancock, B2
Mouncey, P1
Qian, W1
MacLennan, K2
Webb, A1
Alexandrescu, DT1
Karri, S1
Wiernik, PH2
Dutcher, JP2
Sugimoto, T1
Matano, S2
Nishijima, H1
Kakuta, K1
Inamura, K1
Okamura, T1
Munemoto, S1
Satoh, S1
Nair, R1
Prabhash, K1
Sengar, M1
Bakshi, A1
Gujral, S1
Gupta, S1
Parikh, P1
Robak, T3
Lech-Maranda, E2
Janus, A1
Blonski, J1
Wierzbowska, A1
Gora-Tybor, J3
Weide, R1
Hess, G1
Köppler, H1
Heymanns, J1
Thomalla, J1
Aldaoud, A1
Losem, C1
Schmitz, S1
Haak, U1
Huber, C1
Yamanaka, R1
Homma, J1
Sano, M1
Tsuchiya, N1
Yajima, N1
Takahashi, H1
Shinbo, Y1
Hasegawa, A1
Saitoh, T1
Tanaka, R1
Morrison, VA2
Musuraca, G2
Vitolo, U1
Perrotti, A1
Fina, M2
Psyrri, A1
Tsatalas, C2
Anagnostopoulos, A2
Xiros, N1
Dimopoulos, MA3
Lü, SQ1
Yang, JM1
Song, XM1
Chen, L1
Zhang, WP1
Ni, X1
Xu, XQ1
Wang, JM1
Magnus, B1
Andersson, T1
Tomas, A1
Ahlbom, A1
Anders, A1
Eva, O1
Pulsoni, A1
Perotti, A1
De Luca, S1
Fabbri, A1
Voso, MT2
Fattori, P1
Ronconi, S1
Cabras, MG1
Marchi, E1
Piccaluga, PP1
Errante, D5
Bianco, A2
Aversa, SML1
Salvagno, L3
Karaoğuz, H1
Cay, F1
Arican, A1
Haas, R9
Ehrhardt, R1
Witt, B4
Goldschmidt, H5
Hohaus, S2
Pförsich, M1
Ehrlich, H1
Färber, L1
Hunstein, W7
Swan, F3
Pate, O2
Moos, M5
Karcher, A2
Möhle, R3
Frühauf, S1
Flentje, M3
Wannenmacher, M4
Barista, I2
Tekuzman, G2
Firat, D2
Baltali, E1
Kansu, E1
Kars, A2
Ozisik, Y1
Ruacan, S1
Uzunalimoğlu, B1
Karaağaoğlu, E1
Avilés, A1
Díaz-Maqueo, JC2
Talavera, A1
Nambo, MJ1
García, EL1
Norum, J1
Aasebø, U1
De Lena, M2
Ditonno, P1
Lorusso, V2
Brandi, M1
Timurian, A1
Marzullo, F1
Ventrella, V1
Pellecchia, A1
Bendandi, M5
de Ridder, M1
van der Lelie, H1
Nieuwenhuis, K2
Schouten, H1
Mulder, A1
van Reijswoud, I1
Hop, W2
Lowenberg, B3
Cabanillas, FC1
Velasquez, W1
Bezwoda, W1
Rastogi, RB1
Erazo Valla, A1
Pavlovsky, S2
Morioka, H1
Resegotti, L1
Rueckle, H1
Somoza, N2
Moreno-Nogueira, JA1
Kawano, Y1
Takaue, Y1
Saito, S1
Sato, J1
Shimizu, T1
Suzue, T1
Hirao, A1
Okamoto, Y1
Abe, T1
Watanabe, T1
Kohda, K1
Tsuji, A1
Takayanagi, N1
Takeda, M1
Hayashi, S1
Takimoto, R1
Fujisaki, Y1
Tsuji, Y1
Ezoe, A1
Nakazawa, O1
Lepage, E4
Gisselbrecht, C4
Haioun, C3
Sebban, C2
Tilly, H3
Bosly, A3
Morel, P3
Herbrecht, R2
Reyes, F3
Coiffier, B3
Takeshima, M1
Nakamura, S1
Mochizuki, Y1
Hattori, N1
Kaya, H1
Otake, S1
Okabe, Y1
Okumura, H1
Yoshida, T1
Khalil, A1
Ciobanu, N1
Sparano, JA1
Gucalp, R1
Abate, G1
Tafuto, S1
Marcacci, G1
Corazzelli, G1
Fimiani, P1
Monda, VM1
Gailli, E1
D'Andrea, P1
Iaccarino, G1
Bernard, T1
Johnson, SA1
Prentice, AG1
Jones, L1
Phillips, MJ1
Newland, AC1
Buzzoni, R2
Colleoni, M1
Nelli, P1
Nolè, F1
Bajetta, E2
Obrist, R1
Coutts, A1
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Toghill, PJ1
Moloney, AJ1
Hulman, G1
Jenkins, D1
Tirelli, U4
Zagonel, V3
Sorio, R1
Talamini, R2
Carbone, A2
Monfardini, S2
Goss, PE1
Burkes, R2
Rudinskas, L2
King, M2
Chow, W2
Myers, R2
Davidson, M2
Poldre, P2
Crump, M2
Sutton, D2
Schlaifer, D2
Attal, M2
Huguet, F2
Canal, P2
Laurent, G2
Pris, J1
Koch, P3
Nahler, M4
Herrmann, R4
Mulder, AH1
Michiels, JJ2
Blijham, G1
van de Lelie, J1
Raemakers, JW1
van der Heul, C1
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Keating, M1
Lafioniatis, SN1
Bezwoda, WR1
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Seymour, L1
Dansey, R1
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Prescott, RJ1
Leonard, RC1
Matsuura, Y1
Nakamura, H1
Kogure, K1
Fukazawa, M1
Okuyama, Y1
Kawano, E1
Ishii, A1
Nishimura, M1
Hashimoto, S1
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Haak, HL1
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Kerkhofs, H1
Chatelut, E1
Guichard, S1
Muller, C1
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Chisesi, T3
Cheson, BD1
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Sherlaw-Johnson, C1
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Cawley, JC1
Goss, P1
Long, GD1
Negrin, RS2
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Blume, KG2
Chao, NJ1
Landys, KE2
Berg, GE1
Torgerson, JS1
Klingenstierna, HA1
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Johansson, BR1
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Tzeng, CH3
Chiou, TJ3
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Döhner, H1
Murea, S2
Spina, M1
Gastaldi, R1
Nigra, E1
Nosari, AM1
Magnani, G1
Vaccher, E1
Tiemann, M2
Parwaresch, R2
Stein, H2
Trümper, L2
Reuss-Borst, M2
Tirier, C1
Neubauer, A2
Kreuser, ED2
Dietzfelbinger, H1
Engert, A1
Stauder, R1
Eimermacher, H1
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Kosty, M1
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Gibelin, P1
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Hatake, K1
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Miura, Y1
Bellesi, G1
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Fusco, II1
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Brittinger, G1
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Bastion, Y1
Brice, P1
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Ballestrero, A2
Ferrando, F2
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Basta, P1
Gonella, R2
Esposito, M1
Vannozzi, MO1
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Friedman, D1
Puglisi, M1
Brema, F1
Mela, GS1
Sessarego, M2
Patrone, F2
Rodriguez-Monge, EJ1
Hoskin, PJ1
Aydogdu, I1
Koc, H1
Ilhan, O1
Gurman, G1
Akan, H1
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Uysal, A1
Ozerol, E1
Van Glabbeke, M1
Teodorovic, I1
Kluin-Nelemans, JC1
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Rosti, G1
Somers, R1
Noordijk, EM1
Keating, MJ1
Merli, F1
Federico, M1
Avanzini, P1
Ilariucci, F1
Stelitano, C1
Iannitto, E1
Colombi, M1
Vallisa, D1
Santagati, G1
Picinini, L1
Wöltjen, HH1
Terhardt-Kasten, E1
Busch, M1
Kaiser, U1
Hanrath, RD1
Middeke, H1
Helm, G1
Bairey, O1
Gabbay, U1
Blickstein, D1
Stark, P1
Prokocimer, M1
Epstein, O1
Shaklai, M1
Lahav, J1
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Colomer, R1
Rodriguez-Diaz Pavón, J1
Dong, K1
Moon, T1
Ilias, I1
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Celik, I1
Güler, N1
Ozyilkan, O1
Hayran, M1
Rafel, M1
Esteve, J1
Cervantes, F1
Velasco, M1
Serra, A1
Campo, E1
Montserrat, E1
Yau, JC1
Germond, C1
Gluck, S1
Cripps, C1
Verma, S1
Burns, BF1
Koski, TM1
Lister, DC1
Goss, GD1
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Korístek, Z1
Vásová, I1
Müllerová, I1
Král, Z1
Navrátil, M1
Klabusay, M1
Vorlícek, J1
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Hejlová, N1
Penka, M1
Krahulcová, E1
Tomíska, M1
Adam, Z1
Hájek, R1
Kersten, MJ1
Verduyn, TJ1
Reiss, P1
Evers, LM1
de Wolf, F1
van Oers, MH1
Schulz, R1
Martin, S2
Benner, A1
Plantier-Colcher, I1
Simon, M1
Detourmignies, L1
Jouet, JP1
Fenaux, P1
Bauters, F1
Bachier, C1
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Sarris, AH3
Weber, D1
Urbańska-Ryś, H1
Krykowski, E1
Bremnes, RM1
Bremnes, Y1
Dønnem, T1
Rodriguez, J2
Santiago, M1
Bocchia, M1
Tomlinson, J1
Tighe, M1
Johnson, S1
Stone, R1
Nicholson, AG1
Rule, S1
Haq, R1
Sawka, CA1
Franssen, E1
Berinstein, NL1
Tarella, C1
Caracciolo, D1
Corradini, P1
Zallio, F1
Ladetto, M1
Cuttica, A1
Rossi, G1
Novero, D1
Gavarotti, P1
Pileri, A1
Orcioni, GF1
Cellini, C1
Pileri, SA1
Mounier, N1
Cole, BF1
Marit, G1
Bouabdallah, R1
Ravoet, C1
Salles, G1
Pantel, G1
Weis, M1
Schmidt, P1
Ho, AD5
Doorduijn, JK1
Spruit, P1
van't Veer, M1
Budel, L1
Ghio, R1
Johnston, LJ1
Stockerl-Goldstein, KE1
Hu, WW1
Hoppe, RT1
Horning, SJ1
Nair, JS1
Traganos, F1
Tse-Dinh, YC1
Santini, G2
Nati, S1
Spriano, M1
Gallamini, A1
Pierluigi, D1
Congiu, AM2
Truini, M1
Rubagotti, A1
Vimercati, R1
Rossi, E1
Sertoli, MR1
Mattei, D1
Marino, G1
Peters, FP1
Lalisang, RI1
Fickers, MM1
Erdkamp, FL1
Wils, JA1
Houben, SG1
Wals, J1
Polistena, P1
Contu, A2
Coser, P1
Indrizzi, L1
Leoni, P1
Majolino, I1
Porcellini, A1
Zambaldi, G1
Rizzoli, V1
Mainwaring, PN1
Gregory, W1
Norton, AJ1
Hudson, GV1
Błoński, JZ1
Kasznicki, M1
Wilder, RB1
Tucker, SL1
Ha, CS1
Hess, MA1
Cabanillas, FF1
Cox, JD1
Kröger, N1
Kroschinsky, F1
Herbst, R1
Naumann, R1
Friedrichsen, K1
Ehninger, G1
Zander, AR1
Ribeiro, RC1
Fletcher, BD1
Kennedy, W1
Harrison, PL1
Neel, MD1
Kaste, SC1
Sandlund, JT1
Rubnitz, JE1
Razzouk, BI1
Relling, MV1
Pui, CH1
Vose, J1
Modiano, M1
Kraemer, K1
Rifkin, R1
Rubin, A1
Menduni, T1
Ghalie, R1
Lichtman, SM1
Kolitz, J1
Budman, DR1
Schulman, P1
Vinciguerra, V1
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Ford, JM1
Fridman, M1
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Gerke, P1
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Papageogriou, E1
Papasavvas, P1
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Poliwoda, H1
Santarelli, MT2
Erazo, A1
Diaz Maqueo, JC1
Lluesma Goñalons, M1
Cervantes, G1
Garcia Vela, EL1
Corrado, C1
Magnasco, H1
Takagi, T1
Sakai, C1
Oguro, M1
Case, DC2
Carey, RW1
Anderson, J1
Gottlieb, A1
Guglielmi, C1
Amadori, S1
Mandelli, F1
De Cicco, M1
van de Loo, J2
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Paradiso, A1
Guida, M1
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Johansson, B1
Kimby, E1
Lindemalm, C1
Silver, RT1
Wheeler, RH1
Stein, RS1
Stuart, JJ1
Peterson, BA1
Rivkin, SE1
Golomb, HM1
Jungerová, J1
Koza, V1
Cepelák, V1
Del Valle, F3
Engelhard, M2
Rückle, H3
Schlimok, G3
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Andreesen, R2
Fiedler, W2
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Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Study of Fludarabine and Mitoxantrone, Followed by GM-CSF(Granulocyte-macrophage Colony-stimulating Factor) and Rituximab in Patients With Low Grade Non-Hodgkins Lymphoma: An Analysis of Efficacy and Tolerability[NCT00208975]Phase 215 participants (Actual)Interventional2002-07-31Terminated (stopped due to slow accrual)
Phase II Study Treatment of High Risk Non-Hodgkin's Lymphomas[NCT00869284]Phase 245 participants (Actual)Interventional1994-10-31Completed
Phase II Study for Use of Oral Fludarabine Plus Cyclophosphamide and Rituximab Followed by Zevalin as Front-Line Treatment for Non-Follicular Indolent Lymphomas.[NCT00354822]Phase 225 participants (Actual)Interventional2005-08-31Terminated (stopped due to Inability to recruit in time a sufficient number of patients)
A Phase I Trial of Autologous CLL B Cells Transduced to Express Chimeric CD154 (ISF35)[NCT00779883]Phase 19 participants (Actual)Interventional2006-06-30Completed
A Phase 1B Extension Trial to Allow Repeat Dosing of Autologous CLL B Cells Transduced to Express Chimeric CD154 (ISF35) in Subjects Previously Treated in MDACC Protocol 2004-0914[NCT00783588]Phase 14 participants (Actual)Interventional2007-05-31Completed
A Phase II, Open-Label, Prospective, Multicenter Study to Evaluate the Efficacy and Safety of Subsequent Treatment With the Zevalin (Ibritumomab Tiuxetan) Study in Patients With Follicular Grade I-II Lymphoma After 4 Cycles of Fludarabine-Mitoxantrone-Rit[NCT00859001]Phase 255 participants (Actual)InterventionalCompleted
Randomized Phase II Study of Dose-Adjusted EPOCH-Rituximab-Bortezomib (EPOCH-R-B) Induction Followed by Bortezomib Maintenance Versus Observation in Untreated Mantle Cell Lymphoma With Microarray Profiling and Proteomics[NCT00114738]Phase 253 participants (Actual)Interventional2005-06-15Completed
A Prospective, Open, Randomized Controlled, Multi-center Phase III Clinical Trial Comparing High-dose Epirubicin and Standard-dose Epirubicin in R±CEOP in Newly Diagnosed Young Patients With Medium/High-risk Diffuse Large B-cell Lymphoma[NCT03151044]Phase 3408 participants (Anticipated)Interventional2016-07-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Patients's Who Had Complete Response and Partial Response to the Treatment of Fludarabine and Cyclophosphamide Followed by GM-CSF and Rituximab.

"Complete Response (CR): Disappearance of all clinical evidence of active tumor for a minimum of eight weeks and absence of any symptoms related to the tumor.~Partial Response (PR):50% decrease in the sum of the product diameters of all lesions that persist for at least four weeks. No lesion can increase in size and no new lesion can appear during this period.~Stable disease (SD):A tumor that is neither growing nor shrinking.No new tumors have developed" (NCT00208975)
Timeframe: 6 months

,
Interventionparticipants (Number)
Complete ResponsePartial ResponseStable Disease
Chronic Lymphocytic Leukemia421
Non Hodgkin Lymphoma520

Count of Participants With Serious and Non-Serious Adverse Events

Here is the count of participants with serious and non-serious adverse events assessed by the Common Terminology Criteria in Adverse Events (CTCAE v4.0). A non-serious adverse event is any untoward medical occurrence. A serious adverse event is an adverse event or suspected adverse reaction that results in death, a life threatening adverse drug experience, hospitalization, disruption of the ability to conduct normal life functions, congenital anomaly/birth defect or important medical events that jeopardize the patient or subject and may require medical or surgical intervention to prevent one of the previous outcomes mentioned. (NCT00114738)
Timeframe: Date treatment consent signed to date off study, approximately 143 months and 7 days

InterventionParticipants (Count of Participants)
EPOCH-R+Bortezomib53

Median Overall Survival (OS)

Overall Survival is the time between the first day of treatment to the day of death. The primary evaluation will be a Kaplan-Meier analysis with a two tailed log rank test. (NCT00114738)
Timeframe: up to 9.9 years

InterventionMonths (Median)
EPOCH-R+Bortezomib80.4

Overall Progression Free Survival

Time interval from start of treatment to documented evidence of disease progression. Progression is defined by at least one of the following: ≥50% increase in the sum of the products of at least two lymph nodes, appearance of new lymph nodes, ≥50% increase in the size of the liver and/or spleen as determined by measurement below the respective costal margin, appearance of new palpable hepatomegaly or splenomegaly that was not previously present, and ≥50% increase in the absolute number of circulating lymphocytes. (NCT00114738)
Timeframe: up to 9.9 years

InterventionMonths (Median)
EPOCH-R+Bortezomib29.3

Overall Survival

Overall Survival is the time between the first day of treatment to the day of death. The primary evaluation will be a Kaplan-Meier analysis with a two tailed log rank test. (NCT00114738)
Timeframe: up to 9.9 years

InterventionMonths (Median)
Bortezomib Maintenance78.6
Observation87.5
Not Randomized31.6

Progression Free Survival (PFS)

Time interval from start of treatment to documented evidence of disease progression. Progression is defined by at least one of the following: ≥50% increase in the sum of the products of at least two lymph nodes, appearance of new lymph nodes, ≥50% increase in the size of the liver and/or spleen as determined by measurement below the respective costal margin, appearance of new palpable hepatomegaly or splenomegaly that was not previously present, and ≥50% increase in the absolute number of circulating lymphocytes.The primary evaluation will be a Kaplan-Meier analysis with a two tailed log rank test. (NCT00114738)
Timeframe: up to 5 years

InterventionMonths (Median)
Bortezomib Maintenance27.2
Observation33.5
Not Randomized7.8

Clinical Response

Clinical response is assessed by the response criteria for lymphomas and is defined as a fraction of patients who have a complete response (CR) or a complete response (CR) + partial response (PR). A complete response is disappearance of all detectable clinical and radiographic evidence of disease and disappearance of all disease-related symptoms if present before therapy, and normalization of those biochemical abnormalities (e.g. lactate dehydrogenase) definitely assignable to the lymphoma. Partial response is ≥50% decreased in the sum of the products of the greatest diameters of 6 largest dominant nodes or nodal masses. No increase in size of nodes, liver or spleen and no new sites of disease. Progressive disease is defined by at least one of the following: ≥50% increase in the sum of the products of at least two lymph nodes appearance of new lymph nodes, ≥50% increase in the size of the liver and/or spleen, ≥50% increase in the absolute number of circulating lymphocytes. (NCT00114738)
Timeframe: up to 22 weeks after initiation of therapy

InterventionPercentage of patients (Number)
Overall Response (CR+PR)Complete ResponseStable DiseaseProgressive DiseaseNot Evaluable
EPOCH-R+Bortezomib92.586.73.81.91.9

Reviews

15 reviews available for mitoxantrone and Diffuse Mixed Small and Large Cell Lymphoma

ArticleYear
Fludarabine combination therapy for the treatment of chronic lymphocytic leukemia.
    Clinical lymphoma, 2002, Volume: 3, Issue:1

    Topics: Adolescent; Adult; Aged; Alemtuzumab; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodie

2002
Updated meta analysis finds that interferon-alpha improves progression-free and overall survival in low-grade non-Hodgkin's lymphoma when administered with chemotherapy that contains anthracycline or mitoxantrone.
    Clinical lymphoma, 2002, Volume: 3, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Clinical Trials as Topic; D

2002
Rituximab plus chemotherapy in follicular and mantle cell lymphomas.
    Seminars in oncology, 2003, Volume: 30, Issue:1 Suppl 2

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy

2003
Primary adrenal lymphoma presenting as Addison's disease: case report and review of the literature.
    Annals of hematology, 2004, Volume: 83, Issue:7

    Topics: Addison Disease; Adrenal Cortex Neoplasms; Aged; Aged, 80 and over; Antineoplastic Combined Chemothe

2004
Treatment of indolent non-Hodgkin's lymphoma with cladribine as single-agent therapy and in combination with mitoxantrone.
    International journal of hematology, 2004, Volume: 79, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cladribine; Humans; Leukemia, Lymphocytic, Chronic,

2004
Non-Hodgkin's lymphoma in the elderly. Part 2: treatment of diffuse aggressive lymphomas.
    Oncology (Williston Park, N.Y.), 2007, Volume: 21, Issue:10

    Topics: Age Factors; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic

2007
CNOP (mitoxantrone) chemotherapy is inferior to CHOP (doxorubicin) in the treatment of patients with aggressive non-Hodgkin lymphoma (meta-analysis).
    European journal of haematology, 2008, Volume: 80, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Humans; Lymphoma, Non

2008
The treatment of non-Hodgkin's lymphoma with mitoxantrone-containing regimens.
    Seminars in oncology, 1995, Volume: 22, Issue:1 Suppl 1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Humans; Lymphom

1995
Prednisone, oral etoposide, and novantrone for treatment of non-Hodgkin's lymphoma: a preliminary report.
    Seminars in hematology, 1994, Volume: 31, Issue:2 Suppl 3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Humans; Lymphoma, Non-Hodgk

1994
Factors that influence prognosis of intermediate-grade lymphomas at relapse.
    Cancer treatment and research, 1996, Volume: 85

    Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; beta 2-Microglobulin; Cisplatin;

1996
High-dose cytarabine and mitoxantrone as salvage therapy for refractory non-Hodgkin's lymphoma.
    Japanese journal of clinical oncology, 1997, Volume: 27, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Drug Administr

1997
Low-grade non-Hodgkin's lymphoma--development of a new effective combination regimen (fludarabine, mitoxantrone and dexamethasone; FND).
    European journal of cancer care, 1997, Volume: 6, Issue:4 Suppl

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase II as Topic; Dexamethas

1997
[Treatment of lymphoma in the aged].
    Medicina clinica, 1998, May-02, Volume: 110, Issue:15

    Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubi

1998
[Primary MALT-type lymphoma of the breast].
    Sangre, 1998, Volume: 43, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cycloph

1998
Localized non-Hodgkin's lymphoma of the adrenal and thyroid glands.
    Endocrinologia japonica, 1992, Volume: 39, Issue:3

    Topics: Addison Disease; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Antineoplasti

1992

Trials

121 trials available for mitoxantrone and Diffuse Mixed Small and Large Cell Lymphoma

ArticleYear
High ten-year remission rates following rituximab, fludarabine, mitoxantrone and dexamethasone (R-FND) with interferon maintenance in indolent lymphoma: Results of a randomized Study.
    British journal of haematology, 2017, Volume: 177, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Female; Huma

2017
Combination of GM-CSF With Fludarabine-Containing Regimens in Chronic Lymphocytic Leukemia and Indolent Non-Hodgkin Lymphoma.
    Clinical lymphoma, myeloma & leukemia, 2015, Volume: 15, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide;

2015
Equitoxicity of bolus and infusional etoposide: results of a multicenter randomised trial of the German High-Grade Non-Hodgkins Lymphoma Study Group (DSHNHL) in elderly patients with refractory or relapsing aggressive non-Hodgkin lymphoma using the CEMP r
    Annals of hematology, 2008, Volume: 87, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cycl

2008
Shortened and intensified MJMA: an effective salvage therapy for relapsed and refractory lymphomas and a strong mobilizer of PBSCs.
    Bone marrow transplantation, 2009, Volume: 44, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytarab

2009
Inflammatory (B) symptoms are independent predictors of myelosuppression from chemotherapy in Non-Hodgkin Lymphoma (NHL) patients--analysis of data from a British National Lymphoma Investigation phase III trial comparing CHOP to PMitCEBO.
    BMC cancer, 2009, May-18, Volume: 9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cohort Studies; Cyclophosphamide; D

2009
Long-term outcome of mesna, ifosfamide, mitoxantrone, etoposide (MINE) regimen as a consolidation in patients with aggressive non-Hodgkin lymphoma responding to CHOP.
    Medical oncology (Northwood, London, England), 2010, Volume: 27, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophospha

2010
Long-term follow-up of tandem high-dose therapy with autologous stem cell support for adults with high-risk age-adjusted international prognostic index aggressive non-Hodgkin Lymphomas: a GOELAMS pilot study.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011, Volume: 17, Issue:6

    Topics: Adolescent; Adult; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Prot

2011
Reduced-dose cladribine (2-CdA) plus mitoxantrone is effective in the treatment of mantle-cell and low-grade non-Hodgkin's lymphoma.
    European journal of cancer (Oxford, England : 1990), 2002, Volume: 38, Issue:13

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Disease-Free Survival; Fema

2002
A dose escalation study for salvage chemotherapy in patients with refractory lymphoma prior to high-dose myeloablative therapy with stem cell transplantation.
    Bone marrow transplantation, 2002, Volume: 29, Issue:8

    Topics: Acute Kidney Injury; Adult; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Cy

2002
Randomized trial of 8-week versus 12-week VNCOP-B plus G-CSF regimens as front-line treatment in elderly aggressive non-Hodgkin's lymphoma patients.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2002, Volume: 13, Issue:9

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide

2002
Fludarabine, mitoxantrone, dexamethasone (FND) compared with an alternating triple therapy (ATT) regimen in patients with stage IV indolent lymphoma.
    Blood, 2002, Dec-15, Volume: 100, Issue:13

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; beta 2-Microglobulin; Bleomycin; Cispla

2002
[Increased response rate with rituximab in relapsed and refractory follicular and mantle cell lymphomas -- results of a prospective randomized study of the German Low-Grade Lymphoma Study Group].
    Deutsche medizinische Wochenschrift (1946), 2002, Oct-25, Volume: 127, Issue:43

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antimetabolites; Antine

2002
Mitoxantrone/ifosfamide/etoposide salvage regimen with rituximab for in vivo purging in patients with relapsed lymphoma.
    Clinical lymphoma, 2002, Volume: 3, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Antigen

2002
A randomised multicentre trial of modified CHOP versus MCOP in patients aged 65 years and over with aggressive non-Hodgkin's lymphoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:2

    Topics: Administration, Oral; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Pro

2003
Randomized phase III study for the treatment of advanced indolent non-Hodgkin's lymphomas (NHL) and mantle cell lymphoma: chemotherapy versus chemotherapy plus rituximab.
    Annals of hematology, 2003, Volume: 82, Issue:2

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplas

2003
Alternation of epirubicin and mitoxantrone in CHOP-like regimens retains efficacy and reduces overall toxicity in elderly patients with high and intermediate grade non-Hodgkin lymphomas.
    Leukemia & lymphoma, 2002, Volume: 43, Issue:12

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedul

2002
Rituximab plus chemotherapy in follicular and mantle cell lymphomas.
    Seminars in oncology, 2003, Volume: 30, Issue:1 Suppl 2

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy

2003
Combination of fludarabine and mitoxantrone in untreated stages III and IV low-grade lymphoma: S9501.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, May-15, Volume: 21, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Surviva

2003
Rituximab in combination with CNOP chemotherapy in patients with previously untreated indolent non-Hodgkin's lymphoma.
    The hematology journal : the official journal of the European Haematology Association, 2003, Volume: 4, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined

2003
A randomized trial comparing intensified CNOP vs. CHOP in patients with aggressive non-Hodgkin's lymphoma.
    Leukemia & lymphoma, 2003, Volume: 44, Issue:4

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disea

2003
First-line treatment with brief-duration chemotherapy plus rituximab in elderly patients with intermediate-grade non-Hodgkin's lymphoma: phase II trial.
    Clinical lymphoma, 2003, Volume: 4, Issue:1

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemot

2003
Fludarabine, mitoxantrone and dexamethasone in the treatment of indolent B- and T-cell lymphoid malignancies in Chinese patients.
    British journal of haematology, 2004, Volume: 124, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Anti

2004
Fludarabine, mitoxantrone and dexamethasone as front-line therapy in elderly patients affected by newly-diagnosed, low-grade non-Hodgkin's lymphomas with unfavorable prognostic factors: results of a phase II study.
    Leukemia & lymphoma, 2004, Volume: 45, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Female; Humans; Lymphoma, Non-H

2004
Parental longevity and prognosis in elderly patients with aggressive non-Hodgkin's lymphoma.
    Acta oncologica (Stockholm, Sweden), 2004, Volume: 43, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female; Humans;

2004
Fludarabine, cyclophosphamide and mitoxantrone in relapsed or refractory chronic lymphocytic leukemia and low grade non-Hodgkin's lymphoma.
    Leukemia & lymphoma, 2004, Volume: 45, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration S

2004
Fludarabine, cyclophosphamide and mitoxantrone in relapsed or refractory chronic lymphocytic leukemia and low grade non-Hodgkin's lymphoma.
    Leukemia & lymphoma, 2004, Volume: 45, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration S

2004
Fludarabine, cyclophosphamide and mitoxantrone in relapsed or refractory chronic lymphocytic leukemia and low grade non-Hodgkin's lymphoma.
    Leukemia & lymphoma, 2004, Volume: 45, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration S

2004
Fludarabine, cyclophosphamide and mitoxantrone in relapsed or refractory chronic lymphocytic leukemia and low grade non-Hodgkin's lymphoma.
    Leukemia & lymphoma, 2004, Volume: 45, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration S

2004
[VNCOP-B (etoposide, mitoxantrone, cyclophosphamide, vincristine, predonisolone, bleomycin) therapy in elderly patients with aggressive non-Hodgkin lymphoma--a study of efficacy and safety, final report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Drug Administrati

2005
Long-term follow-up of a randomized trial of fludarabine-mitoxantrone, compared with cyclophosphamide, doxorubicin, vindesine, prednisone (CHVP), as first-line treatment of elderly patients with advanced, low-grade non-Hodgkin's lymphoma before the era of
    Annals of oncology : official journal of the European Society for Medical Oncology, 2005, Volume: 16, Issue:3

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease-Free Su

2005
Impact of three courses of intensified CHOP prior to high-dose sequential therapy followed by autologous stem-cell transplantation as first-line treatment in poor-risk, aggressive non-hodgkin's lymphoma: comparative analysis of Dutch-Belgian Hemato-Oncolo
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Jun-01, Volume: 23, Issue:16

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy;

2005
Prospective randomized study comparing MEMID with a chop-like regimen in elderly patients with aggressive non-Hodgkin's lymphoma.
    Oncology, 2005, Volume: 69, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dexamethasone; Disease-Free

2005
Autologous stem cell transplantation following induction therapy with an anthracycline-based regimen including interferon-alpha for low-grade non-Hodgkin's lymphoma.
    Clinical advances in hematology & oncology : H&O, 2004, Volume: 2, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Disease Pr

2004
Mitoxantrone, carboplatin, cytosine arabinoside, and methylprednisolone followed by autologous peripheral blood stem cell transplantation: a salvage regimen for patients with refractory or recurrent non-Hodgkin lymphoma.
    Cancer, 2006, Feb-15, Volume: 106, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytarabine; Drug Res

2006
A phase III trial comparing CHOP to PMitCEBO with or without G-CSF in patients aged 60 plus with aggressive non-Hodgkin's lymphoma.
    British journal of cancer, 2006, Mar-27, Volume: 94, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyc

2006
Cladribine combined with cyclophosphamide and mitoxantrone is an active salvage therapy in advanced non-Hodgkin's lymphoma.
    Leukemia & lymphoma, 2007, Volume: 48, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cyclopho

2007
High anti-lymphoma activity of bendamustine/mitoxantrone/rituximab in rituximab pretreated relapsed or refractory indolent lymphomas and mantle cell lymphomas. A multicenter phase II study of the German Low Grade Lymphoma Study Group (GLSG).
    Leukemia & lymphoma, 2007, Volume: 48, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Anti

2007
Salvage immuno-chemotherapy with a combination of rituximab, high-dose cytarabine, mitoxantrone and dexamethasone for patients with primary CNS lymphoma: a preliminary study.
    Leukemia & lymphoma, 2007, Volume: 48, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined

2007
A phase 2 trial of fludarabine and mitoxantrone chemotherapy followed by yttrium-90 ibritumomab tiuxetan for patients with previously untreated, indolent, nonfollicular, non-Hodgkin lymphoma.
    Cancer, 2008, Feb-15, Volume: 112, Issue:4

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Fem

2008
Phase II study of low-grade non-Hodgkin lymphomas with fludarabine and mitoxantrone followed by rituximab consolidation: promising results in marginal zone lymphoma.
    Leukemia & lymphoma, 2008, Volume: 49, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Disease-Free Survival; Female; Humans; Lymphoma, B-Cell, Marginal Zo

2008
Fludarabine and mitoxantrone followed by yttrium-90 ibritumomab tiuxetan in previously untreated patients with follicular non-Hodgkin lymphoma trial: a phase II non-randomised trial (FLUMIZ).
    The Lancet. Oncology, 2008, Volume: 9, Issue:4

    Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Combined Modali

2008
Autografting with peripheral blood stem cells mobilized by sequential interleukin-3/granulocyte-macrophage colony-stimulating factor following high-dose chemotherapy in non-Hodgkin's lymphoma.
    Bone marrow transplantation, 1993, Volume: 12, Issue:6

    Topics: Adult; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Tra

1993
Intensive conventional-dose chemotherapy for stage IV low-grade lymphoma: high remission rates and reversion to negative of peripheral blood bcl-2 rearrangement.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5 Suppl 2

    Topics: Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Biomark

1994
Effect of granulocyte colony-stimulating factor in patients with diffuse large cell lymphoma treated with intensive chemotherapy.
    Leukemia & lymphoma, 1994, Volume: 15, Issue:1-2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Dise

1994
CEOP-B alternated with VIMB in intermediate-grade and high-grade non-Hodgkin's lymphoma: a pilot study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:4

    Topics: Actuarial Analysis; Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocol

1995
FMP regimen (fludarabine, mitoxantrone, prednisone) as therapy in recurrent low-grade non-Hodgkin's lymphoma.
    European journal of haematology, 1995, Volume: 55, Issue:4

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Sc

1995
Comparison of doxorubicin and mitoxantrone in the treatment of elderly patients with advanced diffuse non-Hodgkin's lymphoma using CHOP versus CNOP chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:10

    Topics: Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined

1995
Long-term results of a multicentre randomised, comparative phase III trial of CHOP versus CNOP regimens in patients with intermediate- and high-grade non-Hodgkin's lymphomas. Novantrone International Study Group.
    European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Di

1995
[NEO-MACOP-B chemotherapy for the treatment of advanced-stage aggressive non-Hodgkin's lymphoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:14

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Eto

1993
Prognostic significance of received relative dose intensity in non-Hodgkin's lymphoma patients: application to LNH-87 protocol. The GELA. (Groupe d'Etude des Lymphomes de l'Adulte).
    Annals of oncology : official journal of the European Society for Medical Oncology, 1993, Volume: 4, Issue:8

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone

1993
[MMIP chemotherapy for the treatment of the relapsed and refractory non-Hodgkin's lymphoma].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1995, Volume: 36, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Ifos

1995
Pilot study of high-dose mitoxantrone and busulfan plus autologous bone transplantation in patients with advanced malignancies.
    Bone marrow transplantation, 1995, Volume: 15, Issue:1

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Bone Marrow Trans

1995
Mitoxantrone, chlorambucil and prednisolone in the treatment of non-Hodgkin's lymphoma.
    Leukemia & lymphoma, 1994, Volume: 15, Issue:5-6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; Humans; Lymphoma,

1994
Results of a salvage regimen in refractory or relapsed non-Hodgkin's lymphoma.
    Leukemia & lymphoma, 1994, Volume: 14, Issue:1-2

    Topics: Adult; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cis

1994
Non-Hodgkin's lymphoma in elderly patients: a phase II study of MCOP chemotherapy in patients aged 70 years or over with intermediate- or high-grade histology.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:9

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy;

1994
Mitoxantrone in combination with etoposide and prednimustine in patients older than 70 years with unfavorable non-Hodgkin's lymphoma: a prospective study in 52 patients.
    Seminars in hematology, 1994, Volume: 31, Issue:2 Suppl 3

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy;

1994
Prednisone, oral etoposide, and novantrone for treatment of non-Hodgkin's lymphoma: a preliminary report.
    Seminars in hematology, 1994, Volume: 31, Issue:2 Suppl 3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Humans; Lymphoma, Non-Hodgk

1994
New aspects in the treatment of advanced low-grade non-Hodgkin's lymphomas: prednimustine/mitoxantrone versus cyclophosphamide/vincristine/prednisone followed by interferon alfa versus observation only--a preliminary update of the German Low-Grade Lymphom
    Seminars in hematology, 1994, Volume: 31, Issue:2 Suppl 3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Germany;

1994
Full-dose chemotherapy for non-Hodgkin's lymphoma in the elderly. Dutch Hematology-Oncology in Adults Study Group.
    Seminars in hematology, 1994, Volume: 31, Issue:2 Suppl 3

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubic

1994
Phase I study of the combination of fludarabine, mitoxantrone, and dexamethasone in low-grade lymphoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Female; Hematopoiesis; Humans; Lympho

1994
NOPE for relapsed aggressive diffuse non-Hodgkin's lymphoma.
    Leukemia & lymphoma, 1993, Volume: 10, Issue:4-5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Heart Failure; Humans; Lymphoma,

1993
Pilot study and randomised trial of mitozantrone and ifosfamide for relapsed non-Hodgkin's lymphoma. Scotland and Newcastle Lymphoma group (SNLG) Working Party on Therapy.
    Leukemia & lymphoma, 1993, Volume: 11, Issue:1-2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Ifosfamide; Lymphoma, N

1993
[A combination chemotherapy of mitoxantrone, etoposide, carboplatin, and prednisolone (MECP) in recurrent or refractory non-Hodgkin's lymphomas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols

1994
Mitoxantrone, teniposide, chlorambucil and prednisone (MVLP) for relapsed non-Hodgkin's lymphoma. The impact of advanced age and performance status.
    The Netherlands journal of medicine, 1993, Volume: 42, Issue:3-4

    Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophospha

1993
Plasma and cellular pharmacokinetics of mitoxantrone in high-dose chemotherapeutic regimen for refractory lymphomas.
    Cancer research, 1993, Oct-15, Volume: 53, Issue:20

    Topics: Adult; Dose-Response Relationship, Drug; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Non-Hodgkin; M

1993
A phase II trial of a chemotherapy combination in elderly patients with aggressive lymphoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1993, Volume: 4, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Etoposide

1993
The rationale of therapy with mitoxantrone in non-Hodgkin's lymphoma. The Non-Hodgkin's Lymphoma Co-operative Study Group, (NHLCSG) Italy.
    Leukemia & lymphoma, 1993, Volume: 9, Issue:1-2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cyclophosphamide;

1993
P-COMM-B induction chemotherapy in intermediate and high grade non-Hodgkin's lymphoma.
    Leukemia & lymphoma, 1995, Volume: 18, Issue:1-2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide

1995
A phase II trial of prednisone, oral etoposide, and novantrone (PEN) as initial treatment of non-Hodgkin's lymphoma in elderly patients.
    Leukemia & lymphoma, 1995, Volume: 18, Issue:1-2

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Etopo

1995
High-dose cytarabine and mitoxantrone as salvage therapy for refractory non-Hodgkin's lymphoma.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1996, Volume: 57, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Lymphoma, N

1996
High-dose therapy with peripheral blood progenitor cell transplantation in low-grade non-Hodgkin's lymphoma.
    Bone marrow transplantation, 1996, Volume: 17, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Bone Marrow Diseases; Carmu

1996
Second-line chemotherapy in human immunodeficiency virus-related non-Hodgkin's lymphoma: evidence of activity of a combination of etoposide, mitoxantrone, and prednimustine in relapsed patients.
    Cancer, 1996, May-15, Volume: 77, Issue:10

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; HIV Infections; Humans; Ly

1996
Prednimustine, mitoxantrone (PmM) vs cyclophosphamide, vincristine, prednisone (COP) for the treatment of advanced low-grade non-Hodgkin's lymphoma. German Low-Grade Lymphoma Study Group.
    Leukemia, 1996, Volume: 10, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease-Free Survival

1996
A new protocol (MiCEP) for the treatment of intermediate or high-grade non-Hodgkin's lymphoma in the elderly.
    Leukemia & lymphoma, 1996, Volume: 20, Issue:5-6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease-Free Survival; Etopo

1996
Myeloablative therapy with blood stem cell transplantation is effective in mantle cell lymphoma.
    Leukemia, 1996, Volume: 10, Issue:12

    Topics: Adult; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Combined Modal

1996
Benefit of autologous bone marrow transplantation over sequential chemotherapy in poor-risk aggressive non-Hodgkin's lymphoma: updated results of the prospective study LNH87-2. Groupe d'Etude des Lymphomes de l'Adulte.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplant

1997
Randomized trial with or without granulocyte colony-stimulating factor as adjunct to induction VNCOP-B treatment of elderly high-grade non-Hodgkin's lymphoma.
    Blood, 1997, Jun-01, Volume: 89, Issue:11

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Etop

1997
Fludarabine-mitoxantrone combination-containing regimen in recurrent low-grade non-Hodgkin's lymphoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Female; Humans;

1997
High-dose cytarabine and mitoxantrone as salvage therapy for refractory non-Hodgkin's lymphoma.
    Japanese journal of clinical oncology, 1997, Volume: 27, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Drug Administr

1997
High-dose mitoxantrone with peripheral blood progenitor cell rescue: toxicity, pharmacokinetics and implications for dosage and schedule.
    British journal of cancer, 1997, Volume: 76, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Surviv

1997
Weekly chemotherapy using PMitCEBO in the palliation of recurrent non-Hodgkin's lymphoma.
    Acta oncologica (Stockholm, Sweden), 1997, Volume: 36, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide

1997
CHOP is the standard regimen in patients > or = 70 years of age with intermediate-grade and high-grade non-Hodgkin's lymphoma: results of a randomized study of the European Organization for Research and Treatment of Cancer Lymphoma Cooperative Study Group
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease-F

1998
Weekly administration of vincristine, cyclophosphamide, mitoxantrone and bleomycin (VEMB) in the treatment of elderly aggressive non Hodgkin's lymphoma. Gruppo Italiano per lo Studio dei Linfomi.
    Haematologica, 1998, Volume: 83, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide

1998
Mantle-cell lymphomas have more widespread disease and a slower response to chemotherapy compared with follicle-center lymphomas: results of a prospective comparative analysis of the German Low-Grade Lymphoma Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease-Free Survival

1998
Alternating triple therapy for the treatment of intermediate grade and immunoblastic lymphoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1998, Volume: 9, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Cyclophosphamide; Cytarabine;

1998
Phase II trial of MINE as a front-line therapeutic modality in intermediate- and high-grade non-Hodgkin's lymphomas.
    European journal of cancer (Oxford, England : 1990), 1998, Volume: 34, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Humans; Ifosfamide;

1998
Mitoxantrone, prednimustine, and vincristine for elderly patients with aggressive non-Hodgkin's lymphoma.
    American journal of hematology, 1998, Volume: 59, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Lymphoma, N

1998
[Chemotherapy of resistant and recurrent lymphoma based on a combination of ifosfamide and etoposide. Antitumor effects, toxicity and stimulation of peripheral stem cells].
    Casopis lekaru ceskych, 1998, Oct-05, Volume: 137, Issue:19

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Drug Resistance, Neoplasm; Etopos

1998
Treatment of AIDS-related non-Hodgkin's lymphoma with chemotherapy (CNOP) and r-hu-G-CSF: clinical outcome and effect on HIV-1 viral load.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1998, Volume: 9, Issue:10

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Granulocyte Colony-

1998
The VIM3-AraC regimen followed by autologous stem cell transplantation in refractory or relapsing aggressive non-Hodgkin's lymphoma. A prospective study of 71 consecutive cases.
    Leukemia, 1999, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytara

1999
Ninety-six-hour paclitaxel infusion with mitoxantrone and ifosfamide/mesna and consolidation with ESHAP for refractory and relapsed non-Hodgkin's lymphoma.
    Leukemia & lymphoma, 1998, Volume: 32, Issue:1-2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytarabin

1998
Combination regimen of 2-chlorodeoxyadenosine (cladribine), mitoxantrone and dexamethasone (CMD) in the treatment of refractory and recurrent low grade non-Hodgkin's lymphoma.
    Leukemia & lymphoma, 1999, Volume: 32, Issue:3-4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Dexamethasone; Female; Huma

1999
Elderly aggressive-histology non-Hodgkin's lymphoma: first-line VNCOP-B regimen experience on 350 patients.
    Blood, 1999, Jul-01, Volume: 94, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cohort Studies;

1999
Mitoxantrone-DHAP with GM-CSF: an active but myelosuppressive salvage therapy for relapsed/refractory aggressive non-Hodgkin's lymphoma.
    Leukemia & lymphoma, 1999, Volume: 35, Issue:5-6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytarabine; Dexamethasone; D

1999
Phase II study of paclitaxel in combination with mitoxantrone and ifosfamide/mesna for patients with relapsed or refractory non-Hodgkin's lymphoma after failure to cytarabine/cisplatin combination.
    Investigational new drugs, 1999, Volume: 17, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytarabine; Female; Humans;

1999
Efficacy of fludarabine and mitoxantrone (FN) combination regimen in untreated indolent non-Hodgkin's lymphomas.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2000, Volume: 11, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Female; Humans; Lymphoma,

2000
Quality of life-adjusted survival analysis of high-dose therapy with autologous bone marrow transplantation versus sequential chemotherapy for patients with aggressive lymphoma in first complete remission. Groupe d'Etude les Lymphomes de l'Adulte (GELA).
    Blood, 2000, Jun-15, Volume: 95, Issue:12

    Topics: Adult; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow

2000
Etoposide, mitoxantrone and prednisone: a salvage regimen with low toxicity for refractory or relapsed non-Hodgkin's lymphoma.
    Haematologica, 2000, Volume: 85, Issue:8

    Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Ma

2000
High-dose chemotherapy with tandem autologous transplantation as part of the initial therapy for aggressive non-Hodgkin's lymphoma.
    International journal of oncology, 2000, Volume: 17, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined Modality Therapy; Cyclo

2000
Fludarabine in combination with cyclophosphamide or with cyclophosphamide plus mitoxantrone for relapsed or refractory low-grade non-Hodgkin's lymphoma.
    Haematologica, 2001, Volume: 86, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Humans; Lymph

2001
Cemp, a mitoxantrone containing combination, in the treatment of intermediate and high grade non-hodgkin's lymphoma: an effective and non toxic therapeutic alternative for adult and elderly patients.
    Leukemia & lymphoma, 2001, Volume: 41, Issue:1-2

    Topics: Actuarial Analysis; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophospham

2001
Mitoxantrone is superior to doxorubicin in a multiagent weekly regimen for patients older than 60 with high-grade lymphoma: results of a BNLI randomized trial of PAdriaCEBO versus PMitCEBO.
    Blood, 2001, May-15, Volume: 97, Issue:10

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide

2001
Cladribine in combination with mitoxantrone and cyclophosphamide(CMC) in the treatment of heavily pre-treated patients with advanced indolent lymphoid malignancies.
    European journal of haematology, 2001, Volume: 66, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cladribine; Cyclophospha

2001
Radiation therapy after a partial response to CHOP chemotherapy for aggressive lymphomas.
    International journal of radiation oncology, biology, physics, 2001, Jul-01, Volume: 50, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit

2001
Salvage chemotherapy with mitoxantrone, fludarabine, cytarabine, and cisplatin (MIFAP) in relapsing and refractory lymphoma.
    Journal of cancer research and clinical oncology, 2001, Volume: 127, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytarabine; Disease-Fr

2001
Mitoxantrone and fludarabine in the treatment of patients with non-Hodgkin's lymphoma failing primary therapy with a doxorubicinor mitoxantrone-containing regimen.
    Leukemia & lymphoma, 2001, Volume: 40, Issue:3-4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Dise

2001
Treatment of aggressive non-Hodgkin's lymphoma in elderly patients with thiotepa, Novantrone (mitoxantrone), vincristine, prednisone (TNOP).
    American journal of clinical oncology, 2001, Volume: 24, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Lymphoma, N

2001
Fludarabine and mitoxantrone: effective and well-tolerated salvage therapy in relapsed indolent lymphoproliferative disorders.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Hematopoietic Stem Cell Mobiliz

2001
Quantitative real-time polymerase chain reaction for monitoring minimal residual disease in patients with advanced indolent lymphomas treated with rituximab, fludarabine, mitoxantrone, and dexamethasone.
    Seminars in oncology, 2002, Volume: 29, Issue:1 Suppl 2

    Topics: Actins; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chem

2002
Primary treatment of low-grade non-Hodgkin's lymphoma with the combination of fludarabine and mitoxantrone: a phase II study of the Hellenic Cooperative Oncology Group.
    Leukemia & lymphoma, 2002, Volume: 43, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Lymp

2002
Outcome is not improved by the use of alternating chemotherapy in elderly patients with aggressive lymphoma.
    The hematology journal : the official journal of the European Haematology Association, 2001, Volume: 2, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Drug

2001
Efficacy of fludarabine/mitoxantrone/dexamethasone alternating with CHOP in bulky follicular non-Hodgkin's lymphoma.
    Clinical lymphoma, 2002, Volume: 2, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; De

2002
Treatment of intermediate- and high-grade non-Hodgkin's lymphoma using CEOP versus CNOP.
    European journal of haematology, 2002, Volume: 68, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alopecia; Antineoplastic Combined Chemotherapy Protocols

2002
Results of a randomized study of previously-untreated intermediate and high grade lymphoma using CHOP versus CNOP.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1992, Volume: 3, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Do

1992
Phase II trial of ifosfamide/mesna and mitoxantrone in previously treated patients with non-Hodgkin's lymphoma: cancer and leukemia group B study 8753.
    Medical and pediatric oncology, 1992, Volume: 20, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Administration

1992
Phase III comparative trial (m-BACOD v m-BNCOD) in the treatment of stage II to IV non-Hodgkin's lymphomas with intermediate- or high-grade histology.
    Seminars in oncology, 1990, Volume: 17, Issue:6 Suppl 10

    Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide;

1990
A prospective study of a new combination chemotherapy regimen in patients older than 70 years with unfavorable non-Hodgkin's lymphoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocol

1992
Multicenter clinical trial of mitoxantrone in non-Hodgkin's lymphoma and Hodgkin's disease.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991, Volume: 9, Issue:5

    Topics: Drug Evaluation; Female; Heart; Hodgkin Disease; Humans; Lymphoma, Non-Hodgkin; Male; Mitoxantrone;

1991
Mitoxantrone/high-dose Ara-C and recombinant human GM-CSF in the treatment of refractory non-Hodgkin's lymphoma. A pilot study.
    Cancer, 1990, Aug-01, Volume: 66, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colony-Stimulating Factors;

1990
High activity of daily-schedule mitoxantrone in newly diagnosed low-grade non-Hodgkin's lymphomas: a 5-year follow-up.
    Seminars in oncology, 1990, Volume: 17, Issue:6 Suppl 10

    Topics: Adult; Aged; Drug Administration Schedule; Female; Follow-Up Studies; Gated Blood-Pool Imaging; Huma

1990
[Phase II clinical trial on mitoxantrone].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1989, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Aged; Breast Neoplasms; Drug Evaluation; Female; Humans; Leukopenia; Lymphoma, No

1989
[Mitoxantrone containing multi-drug chemotherapy in the management of malignancies. Collaborative Group for Clinical Trial of Mitoxantrone].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1989, Volume: 11, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Digestive System Neoplasms;

1989
Mitoxantrone: an active agent in refractory non-Hodgkin's lymphomas.
    American journal of clinical oncology, 1988, Volume: 11, Issue:2

    Topics: Adult; Aged; Clinical Trials as Topic; Doxorubicin; Female; Humans; Infusions, Intravenous; Lymphoma

1988
[Mitoxantrone-containing combination chemotherapy in patients with non-Hodgkin's lymphoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophospham

1986

Other Studies

87 other studies available for mitoxantrone and Diffuse Mixed Small and Large Cell Lymphoma

ArticleYear
Demographics and Outome in Paediatric Non-Hodgkin Lymphoma: Single Centre Experience at The Children Hospital Lahore, Pakistan.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2018, Volume: 28, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Child, Preschoo

2018
Substitution of mitoxantrone for doxorubicin in a multidrug chemotherapeutic protocol for first-line treatment of dogs with multicentric intermediate- to large-cell lymphoma.
    Journal of the American Veterinary Medical Association, 2019, Jan-15, Volume: 254, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dog Diseases; Dogs; Doxor

2019
Fludarabine-Mitoxantrone-Rituximab regimen in untreated indolent non-follicular non-Hodgkin's lymphoma: experience on 143 patients.
    Hematological oncology, 2015, Volume: 33, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Surviva

2015
Clinical investigations in aggressive non-Hodgkin lymphoma.
    Clinical advances in hematology & oncology : H&O, 2008, Volume: 6, Issue:9

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplasti

2008
Midtreatment 18F-fluorodeoxyglucose positron-emission tomography in aggressive non-Hodgkin lymphoma.
    Cancer, 2011, Mar-01, Volume: 117, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Antibodies, Monoclonal, Murine-Derived; Anti

2011
CD7+ and CD56+ myeloid/natural killer cell precursor acute leukemia treated with idarubicin and cytosine arabinoside.
    Acta haematologica, 2002, Volume: 108, Issue:1

    Topics: Acute Disease; Aged; Antigens, CD; Antigens, CD7; Antigens, Differentiation, Myelomonocytic; Antigen

2002
CNOP for diffuse aggressive non-Hodgkin's lymphoma: the Nebraska lymphoma study group experience.
    Leukemia & lymphoma, 2002, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubic

2002
A relapsed non-Hodgkin lymphoma presenting as panhypopituitarism successfully treated by chemotherapy.
    Journal of neuro-oncology, 2002, Volume: 59, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Etoposide; Female

2002
Risk and timing of hospitalization for febrile neutropenia in patients receiving CHOP, CHOP-R, or CNOP chemotherapy for intermediate-grade non-Hodgkin lymphoma.
    Cancer, 2003, Dec-01, Volume: 98, Issue:11

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemot

2003
Urinary immunocytology for primary bladder B cell lymphoma.
    Urology, 2004, Volume: 63, Issue:2

    Topics: Aged; Antigens, CD20; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocy

2004
Incidence and predictors of low chemotherapy dose-intensity in aggressive non-Hodgkin's lymphoma: a nationwide study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Nov-01, Volume: 22, Issue:21

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemot

2004
High dose chemotherapy with thiotepa, mitoxantrone and carboplatin (TMJ) followed by autologous stem cell support in 100 consecutive lymphoma patients in a single centre: analysis of efficacy, toxicity and prognostic factors.
    Leukemia & lymphoma, 2004, Volume: 45, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Carboplatin; Disease

2004
Effective treatment of indolent non-hodgkin's lymphomas with mitoxantrone, chlorambucil and prednisone.
    Onkologie, 2005, Volume: 28, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Di

2005
Combined chemotherapy with carmustine, doxorubicin, etoposide, vincristine, and cyclophosphamide plus mitoxantrone, cytarabine and methotrexate with citrovorum factor for the treatment of aggressive non-Hodgkin lymphoma: a long-term follow-up study.
    Cancer, 2005, Mar-01, Volume: 103, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclophosphamide; Cyt

2005
An open-label pilot study of pentostatin, mitoxantrone, and rituximab in patients with previously untreated, Stage III or IV, low-grade non-Hodgkin lymphoma.
    Cancer, 2005, Mar-01, Volume: 103, Issue:5

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined

2005
[Use of fludarabin in conjunction with other cytostatics in the treatment of non-Hodgkin lymphoma resistant to standard chemotherapy].
    Voprosy onkologii, 2004, Volume: 50, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration S

2004
Ifosfamide, epirubicin, etoposide (IEV) and autologous peripheral blood progenitor cell transplant: a feasible and effective salvage treatment for lymphoid malignancies.
    Oncology reports, 2005, Volume: 14, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Carm

2005
Mitoxantrone, vinblastine and CCNU: long-term follow-up of patients treated for advanced and poor-prognosis Hodgkin's disease.
    Leukemia & lymphoma, 2006, Volume: 47, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Female; Follow-Up Studies; Humans; Lomustine; Lympho

2006
[Concurrent chemo-radiotherapy for localized refractory non-Hodgkin's lymphoma--report of two cases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; D

2007
The effect of short-term intensive chemotherapy on reactivation of tuberculosis.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Cytarabine; Doxo

2007
[A clinical observation of fludarabine-containing regimens in the treatment of low grade non-Hodgkin's lymphoma].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2007, Volume: 29, Issue:9

    Topics: Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dexa

2007
Comment on: 'Non-Hodgkin's lymphoma in very elderly patients over 80 years. A descriptive analysis of clinical presentation and outcome'.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:7

    Topics: Administration, Oral; Aged, 80 and over; Anemia; Antineoplastic Combined Chemotherapy Protocols; Ble

2008
Mesna/ifosfamide, mitoxantrone, etoposide, bleomycin, vincristine, prednisone (MINE-BOP) combination chemotherapy in the treatment of refractory and relapsed non-Hodgkin's lymphoma.
    Acta oncologica (Stockholm, Sweden), 1995, Volume: 34, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Cytar

1995
Sequential high-dose therapy with peripheral-blood progenitor-cell support in low-grade non-Hodgkin's lymphoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:8

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Base Sequence; Chromosomes, Human, Pair 14; C

1994
Non-Hodgkin's lymphomas in Turkey: eighteen years' experience at the Hacettepe University.
    Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Anemia; Antineoplastic Agents; Ant

1994
Intrapleural bleomycin in the treatment of chylothorax.
    Journal of chemotherapy (Florence, Italy), 1994, Volume: 6, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chylothorax; Cyclo

1994
[Sequential high-dose therapy in patients with low-malignity non-Hodgkin's lymphoma].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1995, Volume: 171, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Cytosine; Filgrastim;

1995
Results of a salvage treatment program for relapsing lymphoma: MINE consolidated with ESHAP.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Cytarabine

1995
Granulocyte colony-stimulating factor (CSF), macrophage-CSF, granulocyte-macrophage CSF, interleukin-3, and interleukin-6 levels in sera from children undergoing blood stem cell autografts.
    Blood, 1993, Feb-01, Volume: 81, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Child; Cytarabine; Dau

1993
Three-year results of MIM salvage treatment for refractory/relapsed intermediate grade NHL.
    European journal of haematology, 1995, Volume: 54, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Humans; Ifosfamide; Lymphoma, Non-Hodgkin; Methotrex

1995
Aggressive non-Hodgkin's lymphoma in elderly patients: where to go from here?
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:9

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease-Free Su

1994
Escalating dose of mitoxantrone with high-dose cyclophosphamide, carmustine, and etoposide in refractory lymphoma patients undergoing autologous bone marrow transplantation.
    Seminars in hematology, 1994, Volume: 31, Issue:2 Suppl 3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Chem

1994
Low grade non-Hodgkin's lymphomas: disease control with mitoxanthrone monotherapy in patients refractory to conventional therapy.
    Leukemia & lymphoma, 1994, Volume: 12, Issue:3-4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Lymphoma, Non-Hodgkin;

1994
Clinical trials referral resource. Acute lymphocytic leukemia.
    Oncology (Williston Park, N.Y.), 1993, Volume: 7, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clin

1993
[Percutaneous drainage of refractory necrotizing tumors: experience in 9 patients].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1995, Volume: 163, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Cystadenocarcinoma; Drainage; Female; His

1995
Multiple cycles of high dose chemotherapy supported by hematopoietic progenitor cells as treatment for patients with advanced malignancies.
    Cancer, 1995, Sep-01, Volume: 76, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Breast Neoplasms; Cyclopho

1995
Bulky centroblastic non-Hodgkin's lymphoma of the cranium vault mimicking brain involvement managed with chemotherapy: a case report.
    Cancer, 1995, Oct-01, Volume: 76, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cyclophosphamide; Diagnosis, Differ

1995
Cladribine and mitoxantrone dose escalation in indolent non-Hodgkin's lymphoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Female; Humans; Lymphoma, N

1996
[Complete regression of cardiac non-Hodgkin's lymphoma after 23 months with chemotherapy].
    Archives des maladies du coeur et des vaisseaux, 1996, Volume: 89, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Echocardiography; Electrocardiogra

1996
Therapy-related leukemia with a novel 21q22 rearrangement.
    Cancer genetics and cytogenetics, 1996, Volume: 90, Issue:1

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chromosomes, Human, Pair 21;

1996
Granulocyte-colony stimulating factor fails to prevent leucopenia caused by CEMP in elderly patients with aggressive lymphoma.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1996, Volume: 86, Issue:12

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Etoposide

1996
[Primary extranodal non-Hodgkin's lymphoma of muscle tissue].
    Recenti progressi in medicina, 1997, Volume: 88, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Extremities; Female; Follow-

1997
Long-term follow-up of platinum-based lymphoma salvage regimens. The M.D. Anderson Cancer Center experience.
    Hematology/oncology clinics of North America, 1997, Volume: 11, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytarabine; Dexamethasone; Disease-Free S

1997
Administration of MINE protocol in untreated patients with intermediate and high grade non-Hodgkin's lymphoma.
    Haematologia, 1997, Volume: 28, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Humans; Ifosfamide;

1997
Levels of proteins C and S do not decline subsequent to first line chemotherapy in lymphoma patients.
    Hematological oncology, 1997, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; alpha-2-Antiplasmin; Antineoplastic Combined Chemotherap

1997
Onycholysis after chemotherapy in a patient with lymphoma.
    Acta dermato-venereologica, 1998, Volume: 78, Issue:4

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Finge

1998
The remission status before and the PCR status after high-dose therapy with peripheral blood stem cell support are prognostic factors for relapse-free survival in patients with follicular non-Hodgkin's lymphoma.
    Leukemia, 1998, Volume: 12, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 14; Chromosomes, Hum

1998
High-grade non-Hodgkin's lymphoma treated in northern Norway--treatment, outcome, and prognostic factors.
    Acta oncologica (Stockholm, Sweden), 1999, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined

1999
Follicular large cell lymphoma: an aggressive lymphoma that often presents with favorable prognostic features.
    Blood, 1999, Apr-01, Volume: 93, Issue:7

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined

1999
Interstitial pneumonitis following mitozantrone, chlorambucil and prednisolone (MCP) chemotherapy.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1999, Volume: 11, Issue:3

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; H

1999
Long-term follow-up of advanced-stage low-grade lymphoma patients treated upfront with high-dose sequential chemotherapy and autograft.
    Leukemia, 2000, Volume: 14, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Cycloph

2000
In vivo depletion of B cells using a combination of high-dose cytosine arabinoside/mitoxantrone and rituximab for autografting in patients with non-Hodgkin's lymphoma.
    British journal of haematology, 2000, Volume: 109, Issue:4

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antine

2000
Toxicity of high-dose sequential chemotherapy and purged autologous hematopoietic cell transplantation precludes its use in refractory/recurrent non-Hodgkin's lymphoma.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2000, Volume: 6, Issue:5A

    Topics: Acute Kidney Injury; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bo

2000
Action of topoisomerase targeting drugs on non-Hodgkin's lymphoma and leukemia. Correlation of clinical and cell culture studies.
    Annals of the New York Academy of Sciences, 2000, Volume: 922

    Topics: Acute Disease; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials,

2000
Treatment of elderly patients with intermediate- and high-grade non-Hodgkin's lymphoma: a retrospective population-based study.
    Annals of hematology, 2001, Volume: 80, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female; Humans;

2001
Magnetic resonance imaging detection of avascular necrosis of the bone in children receiving intensive prednisone therapy for acute lymphoblastic leukemia or non-Hodgkin lymphoma.
    Leukemia, 2001, Volume: 15, Issue:6

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Arthralgia; Arthroplasty, R

2001
Combination therapy with irinotecan (CPT-11), mitoxantrone, and dexamethasone in relapsed or refractory non-Hodgkin's lymphoma: a pilot study.
    Annals of hematology, 2001, Volume: 80, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogen

2001
Patterns of chemotherapy administration in patients with intermediate-grade non-Hodgkin's lymphoma.
    Oncology (Williston Park, N.Y.), 2001, Volume: 15, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease-F

2001
A prolonged APTT in a patient with a low grade malignant NHL - a case report.
    Haematologica, 2002, Volume: 87, Issue:2

    Topics: Anemia; Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Blood Coagulation Factors; C

2002
A combination of mitoxantrone, etoposide and prednisone in elderly patients with non-Hodgkin's lymphoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1992, Volume: 3, Issue:10

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Humans;

1992
[Treatment of elderly patients with hematological malignancies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:11

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit

1992
Non-Hodgkin's lymphomas: a review of the M.D. Anderson experience.
    Seminars in oncology, 1992, Volume: 19, Issue:1 Suppl 1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin

1992
[The use of novantrone in combination with other preparations in hematosarcoma patients].
    Terapevticheskii arkhiv, 1992, Volume: 64, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubic

1992
Prednimustine and mitoxantrone (PmM) in patients with low-grade malignant non-Hodgkin's lymphoma (NHL), chronic lymphocytic leukemia (CLL), and prolymphocytic leukemia (PLL).
    Annals of hematology, 1992, Volume: 64, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Leukemia, Lymphocytic,

1992
[Combination chemotherapy with mitoxantrone, etoposide, vindesine and prednisolone for relapsed or refractory malignant lymphoma: presence of cross-resistance to CHOP therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Res

1992
alpha Interferon maintenance therapy in patients with low-grade non-Hodgkin's lymphomas after cytoreductive chemotherapy with prednimustine and mitoxantrone.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27 Suppl 4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Humans; Inte

1991
[Comparison of two multi-drug chemotherapy regimens based on mitoxantrone and epirubicin in 44 patients with non-Hodgkin's lymphoma].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1991, Volume: 13, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Epirubici

1991
Experience with salvage regimens at M.D. Anderson Hospital.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1991, Volume: 2 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytarabine; Drug Evaluation; Etoposide; F

1991
Ifosfamide plus mitoxantrone as salvage treatment in non-Hodgkin's lymphomas.
    American journal of clinical oncology, 1991, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Ifosfamide;

1991
Serum levels of tumor necrosis factor alpha in patients treated with granulocyte-macrophage colony-stimulating factor.
    Blood, 1990, May-01, Volume: 75, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colony-Stimulating Factors; Cytarabine; Granulocyte-

1990
Mitoxantrone, etoposide, cytarabine and prednisone as salvage therapy for refractory non-Hodgkin lymphoma (NHL) and alternated with CHOP in previously untreated patients with NHL.
    European journal of haematology, 1991, Volume: 46, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubic

1991
[Injections of mitoxantrone, VUFB Praha, in the treatment of acute myeloid leukemia and non-Hodgkin's lymphoma].
    Vnitrni lekarstvi, 1991, Volume: 37, Issue:3

    Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Leukemia, Myelo

1991
Non-Hodgkin's lymphoma. A four-drug regimen suitable for elderly patients with advanced disease.
    Acta oncologica (Stockholm, Sweden), 1990, Volume: 29, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Drug Evaluation; Female; Humans;

1990
Sequential studies on the role of mitoxantrone, high-dose cytarabine, and recombinant human granulocyte-macrophage colony-stimulating factor in the treatment of refractory non-Hodgkin's lymphoma.
    Seminars in oncology, 1990, Volume: 17, Issue:6 Suppl 10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administra

1990
Phase II study of lomustine, cytarabine, mitoxantrone, and prednisone (CAMP) combination chemotherapy for doxorubicin-resistant intermediate- and high-grade malignant non-Hodgkin's lymphoma.
    Seminars in oncology, 1990, Volume: 17, Issue:6 Suppl 10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Doxorubicin;

1990
Treatment of low-grade non-Hodgkin's lymphoma by cytoreductive chemotherapy with prednimustine/mitoxantrone followed by interferon alpha-2b maintenance: results of a clinical phase II study.
    Seminars in oncology, 1990, Volume: 17, Issue:6 Suppl 10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Eval

1990
Full dose chemotherapy in elderly patients with non-Hodgkin's lymphoma: a feasibility study using a mitoxantrone containing regimen.
    British journal of cancer, 1990, Volume: 62, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dose-Resp

1990
Mitoxantrone and high-dose cytarabine as salvage therapy for refractory non-Hodgkin's lymphoma.
    Cancer, 1989, Oct-01, Volume: 64, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation

1989
Intrathecal mitozantrone.
    Lancet (London, England), 1985, Jul-20, Volume: 2, Issue:8447

    Topics: Anthraquinones; Central Nervous System Diseases; Humans; Injections, Spinal; Lymphoma, Non-Hodgkin;

1985
Cardiac damage in autologous bone marrow transplant patients: an autopsy study. Cardiotoxic pretreatment as a major risk factor.
    Klinische Wochenschrift, 1988, Dec-01, Volume: 66, Issue:23

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Bone Marrow Transplantation; Cardiomyopat

1988
[A comparative trial of C-novantrone OP(CNOP) vs C-adriamycin OP(CHOP) in the treatment of stage II-IV malignant lymphoma--the preliminary report].
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1988, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubic

1988
Mitoxantrone in combination with prednimustine in treatment of unfavorable non-Hodgkin lymphoma.
    Investigational new drugs, 1988, Volume: 6, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Lymp

1988
Cyclophosphamide, mitoxantrone, vincristine and prednisone in the treatment of non-Hodgkin's lymphoma.
    Oncology, 1988, Volume: 45, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Humans; Lymphoma, Non-Hodg

1988
Salvage chemotherapy for non-Hodgkin's lymphoma with a combination of mitoxantrone, etoposide, cisplatin, and prednisolone.
    Cancer treatment reports, 1987, Volume: 71, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Female; Humans; L

1987
Weekly mitoxantrone therapy of Hodgkin's disease, non-Hodgkin's lymphoma, and chronic lymphocytic leukemia. A Southeastern Cancer Study Group Trial.
    American journal of clinical oncology, 1987, Volume: 10, Issue:3

    Topics: Adolescent; Adult; Drug Administration Schedule; Drug Evaluation; Female; Hodgkin Disease; Humans; I

1987
Mitoxantrone in the treatment of patients with non-Hodgkin's Lymphoma.
    Cancer treatment reports, 1987, Volume: 71, Issue:12

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Female; Heart Diseases; Hematopoiesis; Humans; Lympho

1987
[Salvage chemotherapy of non-Hodgkin's lymphoma with a four-drug combination of mitoxantrone, etoposide, cisplatin and prednisolone (MEPP)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:3 Pt 1

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etopos

1987