mitoxantrone has been researched along with Diarrhea in 8 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mitoxantrone is a synthetic aminoanthraquinone we have previously reported to be effective for patients with acute leukemia in relapse." | 5.27 | Mitoxantrone and ara-C in previously treated patients with acute myelogenous leukemia. ( Cuttner, J; Dutcher, JP; Holland, JF; Paciucci, PA; Strauman, JJ; Wiernik, PH, 1987) |
| " Ten dogs were given mitoxantrone at a dosage of 5." | 2.67 | Toxicoses associated with the administration of mitoxantrone to dogs with malignant tumors: a dose escalation study. ( Atwater, SW; Bergman, PJ; Chen, C; Ciekot, PA; Moore, AS; Ogilvie, GK; Walters, LM, 1994) |
| "Mitoxantrone is a synthetic aminoanthraquinone we have previously reported to be effective for patients with acute leukemia in relapse." | 1.27 | Mitoxantrone and ara-C in previously treated patients with acute myelogenous leukemia. ( Cuttner, J; Dutcher, JP; Holland, JF; Paciucci, PA; Strauman, JJ; Wiernik, PH, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 5 (62.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Larson, SM | 1 |
| Campbell, NP | 1 |
| Huo, D | 1 |
| Artz, A | 1 |
| Zhang, Y | 1 |
| Gajria, D | 1 |
| Green, M | 1 |
| Weiner, H | 1 |
| Daugherty, C | 1 |
| Odenike, O | 1 |
| Godley, LA | 1 |
| Hyjek, E | 1 |
| Gurbuxani, S | 1 |
| Thirman, M | 1 |
| Sipkins, D | 1 |
| Van Besien, K | 1 |
| Larson, RA | 1 |
| Stock, W | 1 |
| Ogilvie, GK | 2 |
| Moore, AS | 2 |
| Chen, C | 1 |
| Ciekot, PA | 1 |
| Atwater, SW | 1 |
| Bergman, PJ | 1 |
| Walters, LM | 1 |
| Martino, R | 1 |
| Guardia, R | 1 |
| Altés, A | 1 |
| Sureda, A | 1 |
| Brunet, S | 1 |
| Sierra, J | 1 |
| Thurnher, D | 1 |
| Kornfehl, J | 1 |
| Burian, M | 1 |
| Gedlicka, C | 1 |
| Selzer, E | 1 |
| Quint, C | 1 |
| Neuchrist, C | 1 |
| Kornek, GV | 1 |
| Kreisle, WH | 1 |
| Alberts, DS | 1 |
| List, AF | 1 |
| McCloskey, T | 1 |
| Plezia, P | 1 |
| Peng, YM | 1 |
| George, M | 1 |
| Obradovich, JE | 1 |
| Elmslie, RE | 1 |
| Vail, DM | 1 |
| Curtis, CR | 1 |
| Straw, RC | 1 |
| Dickinson, K | 1 |
| Cooper, MF | 1 |
| Withrow, SJ | 1 |
| Hiddemann, W | 1 |
| Büchner, T | 1 |
| Heil, G | 1 |
| Schumacher, K | 1 |
| Diedrich, H | 1 |
| Maschmeyer, G | 1 |
| Ho, AD | 1 |
| Planker, M | 1 |
| Gerith-Stolzenburg, S | 1 |
| Donhuijsen-Ant, R | 1 |
| Paciucci, PA | 1 |
| Dutcher, JP | 1 |
| Cuttner, J | 1 |
| Strauman, JJ | 1 |
| Wiernik, PH | 1 |
| Holland, JF | 1 |
4 trials available for mitoxantrone and Diarrhea
| Article | Year |
|---|---|
Toxicoses associated with the administration of mitoxantrone to dogs with malignant tumors: a dose escalation study.
Topics: Animals; Bone Marrow; Diarrhea; Dog Diseases; Dogs; Female; Follow-Up Studies; Leukocyte Count; Logi | 1994 |
Time sequential chemotherapy for primary refractory or relapsed adult acute myeloid leukemia: results of the phase II Gemia protocol.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Combined Modality | 1999 |
Ifosfamide and mitoxantrone in the treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Anemia; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, | 2001 |
A phase I trial of 14-day continuous intravenous infusion mitoxantrone.
Topics: Adult; Aged; Diarrhea; Drug Evaluation; Female; Gastrointestinal Diseases; Humans; Infusions, Intrav | 1991 |
4 other studies available for mitoxantrone and Diarrhea
| Article | Year |
|---|---|
High dose cytarabine and mitoxantrone: an effective induction regimen for high-risk acute myeloid leukemia (AML).
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chrom | 2012 |
Toxicoses associated with administration of mitoxantrone to dogs with malignant tumors.
Topics: Animals; Anorexia; Bone Marrow; Diarrhea; Dog Diseases; Dogs; Female; Lymphoma; Male; Mitoxantrone; | 1991 |
Treatment of refractory acute lymphoblastic leukemia in adults with high dose cytosine arabinoside and mitoxantrone (HAM).
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation | 1990 |
Mitoxantrone and ara-C in previously treated patients with acute myelogenous leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Diarrhea; Drug Administrati | 1987 |