Page last updated: 2024-10-31

mitoxantrone and Cirrhosis

mitoxantrone has been researched along with Cirrhosis in 4 studies

Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.

Research Excerpts

ExcerptRelevanceReference
"Age is a known susceptibility factor for the cardiotoxicity of several anticancer drugs, including mitoxantrone (MTX)."7.81The age factor for mitoxantrone's cardiotoxicity: multiple doses render the adult mouse heart more susceptible to injury. ( Bastos, Mde L; Carvalho, F; Costa, VM; Dores-Sousa, JL; Duarte, JA; Seabra, V, 2015)
"A 44-year-old man who had achieved a complete remission of malignant peritoneal mesothelioma after the intraperitoneal administration of 25 mg/m2 mitoxantrone presented with clinical and radiological signs of intestinal obstruction suggestive of recurrent disease at about 2 years following the initial treatment."7.68Intestinal obstruction due to diffuse peritoneal fibrosis at 2 years after the successful treatment of malignant peritoneal mesothelioma with intraperitoneal mitoxantrone. ( Gallee, MP; Kroon, BB; Rodenhuis, S; Taal, BG; Vlasveld, LT, 1992)
"Age is a known susceptibility factor for the cardiotoxicity of several anticancer drugs, including mitoxantrone (MTX)."3.81The age factor for mitoxantrone's cardiotoxicity: multiple doses render the adult mouse heart more susceptible to injury. ( Bastos, Mde L; Carvalho, F; Costa, VM; Dores-Sousa, JL; Duarte, JA; Seabra, V, 2015)
"A 44-year-old man who had achieved a complete remission of malignant peritoneal mesothelioma after the intraperitoneal administration of 25 mg/m2 mitoxantrone presented with clinical and radiological signs of intestinal obstruction suggestive of recurrent disease at about 2 years following the initial treatment."3.68Intestinal obstruction due to diffuse peritoneal fibrosis at 2 years after the successful treatment of malignant peritoneal mesothelioma with intraperitoneal mitoxantrone. ( Gallee, MP; Kroon, BB; Rodenhuis, S; Taal, BG; Vlasveld, LT, 1992)
"Mitoxantrone is a new antineoplastic that differs from bleomycin in that it binds to membranes."1.29Comparison of mitoxantrone and tetracycline as pleural sclerosing agents in rabbits. ( Despars, JA; Gruer, SE; Light, RW; Sassoon, C; Vargas, FS; Wang, NS, 1996)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dores-Sousa, JL1
Duarte, JA1
Seabra, V1
Bastos, Mde L1
Carvalho, F1
Costa, VM1
Toledano, A1
Garaud, P1
Serin, D1
Fourquet, A1
Bosset, JF1
Miny-Buffet, J1
Favre, A1
Azria, D1
Body, G1
Le Floch, O1
Calais, G1
Light, RW1
Wang, NS1
Despars, JA1
Gruer, SE1
Sassoon, C1
Vargas, FS1
Vlasveld, LT1
Taal, BG1
Kroon, BB1
Gallee, MP1
Rodenhuis, S1

Trials

1 trial available for mitoxantrone and Cirrhosis

ArticleYear
[Concurrent administration of adjuvant chemotherapy and radiotherapy after breast-conservative surgery enhances late toxicities].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2006, Volume: 10, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemo

2006

Other Studies

3 other studies available for mitoxantrone and Cirrhosis

ArticleYear
The age factor for mitoxantrone's cardiotoxicity: multiple doses render the adult mouse heart more susceptible to injury.
    Toxicology, 2015, Mar-02, Volume: 329

    Topics: Age Factors; Animals; Antineoplastic Agents; Aspartate Aminotransferases; Biomarkers; Body Weight; C

2015
Comparison of mitoxantrone and tetracycline as pleural sclerosing agents in rabbits.
    Lung, 1996, Volume: 174, Issue:6

    Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Fibrosis; Lethal Dose 50; Male; Mi

1996
Intestinal obstruction due to diffuse peritoneal fibrosis at 2 years after the successful treatment of malignant peritoneal mesothelioma with intraperitoneal mitoxantrone.
    Cancer chemotherapy and pharmacology, 1992, Volume: 29, Issue:5

    Topics: Adult; Biopsy; Fibrosis; Humans; Injections, Intraperitoneal; Intestinal Obstruction; Jejunal Diseas

1992