mitoxantrone has been researched along with Chromosome Deletion in 4 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
Chromosome Deletion: Actual loss of portion of a chromosome.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the clinical relevance of multidrug resistance (MDR) phenotype, the intracellular daunorubicin accumulation (IDA) and P-glycoprotein (P-gp) expression were investigated in 87 adult patients with acute leukemia: 69 patients with de novo acute myeloid leukemia (AML), 10 with AML at relapse, and eight with secondary leukemia to myelodysplastic syndromes (MDS-AML)." | 3.69 | Predictive value for treatment outcome in acute myeloid leukemia of cellular daunorubicin accumulation and P-glycoprotein expression simultaneously determined by flow cytometry. ( Feldmann, L; Guerci, A; Guerci, O; Marchal, S; Merlin, JL; Missoum, N; Rose, C; Witz, F, 1995) |
| "We report a patient with acute myelomonocytic leukemia (AMMoL) who showed two independent point mutations of the N-ras gene at codons 12 and 13." | 1.29 | Double mutations of the N-ras gene in a patient with acute myelomonocytic leukemia. ( Hirakawa, K; Horiike, S; Kaneko, H; Kashima, K; Misawa, S; Nakai, H; Nakao, M; Taniwaki, M; Ueda, Y, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guerci, A | 1 |
| Merlin, JL | 1 |
| Missoum, N | 1 |
| Feldmann, L | 1 |
| Marchal, S | 1 |
| Witz, F | 1 |
| Rose, C | 1 |
| Guerci, O | 1 |
| Horiike, S | 1 |
| Misawa, S | 1 |
| Kaneko, H | 1 |
| Nakai, H | 1 |
| Ueda, Y | 1 |
| Nakao, M | 1 |
| Hirakawa, K | 1 |
| Taniwaki, M | 1 |
| Kashima, K | 1 |
| Visani, G | 1 |
| Bernasconi, P | 1 |
| Boni, M | 1 |
| Castoldi, GL | 1 |
| Ciolli, S | 1 |
| Clavio, M | 1 |
| Cox, MC | 1 |
| Cuneo, A | 1 |
| Del Poeta, G | 1 |
| Dini, D | 1 |
| Falzetti, D | 1 |
| Fanin, R | 1 |
| Gobbi, M | 1 |
| Isidori, A | 1 |
| Leoni, F | 1 |
| Liso, V | 1 |
| Malagola, M | 1 |
| Martinelli, G | 1 |
| Mecucci, C | 1 |
| Piccaluga, PP | 1 |
| Petti, MC | 1 |
| Rondelli, R | 1 |
| Russo, D | 1 |
| Sessarego, M | 1 |
| Specchia, G | 1 |
| Testoni, N | 1 |
| Torelli, G | 1 |
| Mandelli, F | 1 |
| Tura, S | 1 |
| Las Heras, G | 1 |
| Ribera, JM | 1 |
| Granada, I | 1 |
| Millá, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 2 Study of Autologous Hematopoietic Cell Transplantation for Core-binding Factor Positive Acute Myeloid Leukemia in the First Complete Remission[NCT01050036] | 39 participants (Anticipated) | Interventional | 2010-01-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for mitoxantrone and Chromosome Deletion
| Article | Year |
|---|---|
The prognostic value of cytogenetics is reinforced by the kind of induction/consolidation therapy in influencing the outcome of acute myeloid leukemia--analysis of 848 patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromoso | 2001 |
3 other studies available for mitoxantrone and Chromosome Deletion
| Article | Year |
|---|---|
Predictive value for treatment outcome in acute myeloid leukemia of cellular daunorubicin accumulation and P-glycoprotein expression simultaneously determined by flow cytometry.
Topics: Acute Disease; Adolescent; Adult; Aged; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemot | 1995 |
Double mutations of the N-ras gene in a patient with acute myelomonocytic leukemia.
Topics: Aclarubicin; Alleles; Antineoplastic Combined Chemotherapy Protocols; Chromosome Deletion; Chromosom | 1995 |
[Acute myeloblastic leukemia 5q-. Clinical and cytogenetic remission by means of intensive chemotherapy].
Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Chromosome Deletion; Chromosomes, Human, | 1991 |