Page last updated: 2024-10-31

mitoxantrone and Choroid Neoplasms

mitoxantrone has been researched along with Choroid Neoplasms in 2 studies

Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.

Choroid Neoplasms: Tumors of the choroid; most common intraocular tumors are malignant melanomas of the choroid. These usually occur after puberty and increase in incidence with advancing age. Most malignant melanomas of the uveal tract develop from benign melanomas (nevi).

Research Excerpts

ExcerptRelevanceReference
"Choroidal metastases from breast cancer represent an unusual metastatic presentation that has been traditionally treated with radiation therapy."2.41Chemotherapy-induced complete regression of choroidal metastases and subsequent isolated leptomeningeal carcinomatosis in advanced breast cancer: a case report and literature review. ( Antonopoulos, M; Kosmas, C; Malamos, NA; Tsavaris, N, 2000)
"Choroidal melanoma has a high mortality rate and responds poorly to existing chemotherapy, but unexpected ex vivo sensitivity of a subset of these tumours to topoisomerase II inhibitors has been noted."1.31Relationship between expression of topoisomerase II isoforms and chemosensitivity in choroidal melanoma. ( Alexander, RA; Cree, IA; de Souza, L; Foss, AJ; Hickson, ID; Hungerford, JL; Myatt, N; Neale, MH; Satherley, K, 2000)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kosmas, C1
Malamos, NA1
Tsavaris, N1
Antonopoulos, M1
Satherley, K1
de Souza, L1
Neale, MH1
Alexander, RA1
Myatt, N1
Foss, AJ1
Hungerford, JL1
Hickson, ID1
Cree, IA1

Reviews

1 review available for mitoxantrone and Choroid Neoplasms

ArticleYear
Chemotherapy-induced complete regression of choroidal metastases and subsequent isolated leptomeningeal carcinomatosis in advanced breast cancer: a case report and literature review.
    Journal of neuro-oncology, 2000, Volume: 47, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast;

2000

Other Studies

1 other study available for mitoxantrone and Choroid Neoplasms

ArticleYear
Relationship between expression of topoisomerase II isoforms and chemosensitivity in choroidal melanoma.
    The Journal of pathology, 2000, Volume: 192, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic A

2000