Page last updated: 2024-10-31

mitoxantrone and Choriocarcinoma

mitoxantrone has been researched along with Choriocarcinoma in 4 studies

Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.

Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).

Research Excerpts

ExcerptRelevanceReference
" As a functional consequence, knockdown of BCRP by siRNAs increased the sensitivity of human choriocarcinoma BeWo cells to mitoxantrone and topotecan by 10."3.72Modulation of breast cancer resistance protein (BCRP/ABCG2) gene expression using RNA interference. ( Beck, WT; Ee, PL; He, X; Ross, DD, 2004)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yu, P1
Diao, W1
Jiang, X1
Chandacham, A1
Kietpeerakool, C1
Khunamornpong, S1
Suprasert, P1
Srisomboon, J1
Charoenkwan, K1
Phongnarisorn, C1
Cheewakraingkrai, C1
Siriaree, S1
Tantipalakorn, C1
Kummu, M1
Sieppi, E1
Wallin, K1
Rautio, A1
Vähäkangas, K1
Myllynen, P1
Ee, PL1
He, X1
Ross, DD1
Beck, WT1

Other Studies

4 other studies available for mitoxantrone and Choriocarcinoma

ArticleYear
A Successfully Treated Metastatic Choriocarcinoma Coexistent With Pregnancy: A Case Report of a 4-Year Follow-Up.
    Medicine, 2016, Volume: 95, Issue:21

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cesarean Section; Choriocarcinoma; Cyclophosp

2016
Successfully conservative treatment of large cervical choriocarcinoma with profuse vaginal bleeding.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2009, Volume: 92, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Cytarabine; Diagnosis, Diffe

2009
Cadmium inhibits ABCG2 transporter function in BeWo choriocarcinoma cells and MCF-7 cells overexpressing ABCG2.
    Placenta, 2012, Volume: 33, Issue:10

    Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cadmium

2012
Modulation of breast cancer resistance protein (BCRP/ABCG2) gene expression using RNA interference.
    Molecular cancer therapeutics, 2004, Volume: 3, Issue:12

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette

2004