mitoxantrone has been researched along with Cell Transformation, Neoplastic in 8 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have identified CICs in a human breast cancer cell line, MX-1, and developed a xenograft model in SCID mice." | 1.42 | Differential remodeling of extracellular matrices by breast cancer initiating cells. ( Chen, CS; Raja, AM; So, PT; Sun, W; Tai, DC; Welsch, RE; Xu, S; Yu, H; Zhuo, S, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Raja, AM | 1 |
| Xu, S | 1 |
| Zhuo, S | 1 |
| Tai, DC | 1 |
| Sun, W | 1 |
| So, PT | 1 |
| Welsch, RE | 1 |
| Chen, CS | 1 |
| Yu, H | 1 |
| Kikuchi, A | 1 |
| Hasegawa, D | 1 |
| Ohtsuka, Y | 1 |
| Hamamoto, K | 1 |
| Kojima, S | 1 |
| Okamura, J | 1 |
| Nakahata, T | 1 |
| Manabe, A | 1 |
| Delforge, M | 1 |
| Demuynck, H | 1 |
| Vandenberghe, P | 1 |
| Verhoef, G | 1 |
| Zachée, P | 1 |
| van Duppen, V | 1 |
| Marijnen, P | 1 |
| Van den Berghe, H | 1 |
| Boogaerts, MA | 1 |
| Creutzig, U | 1 |
| Bender-Götze, C | 1 |
| Ritter, J | 1 |
| Zimmermann, M | 1 |
| Stollmann-Gibbels, B | 1 |
| Körholz, D | 1 |
| Niemeyer, C | 1 |
| Medina, MA | 1 |
| Luque, P | 1 |
| Núñez De Castro, I | 1 |
| Brito-Babapulle, F | 1 |
| Lord, JA | 1 |
| Whitmore, DN | 1 |
| Manandhar, M | 1 |
| Cheng, M | 1 |
| Iatropoulos, MJ | 1 |
| Noble, JF | 1 |
| Jensen, CG | 1 |
| Wilson, WR | 1 |
| Bleumink, AR | 1 |
8 other studies available for mitoxantrone and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Differential remodeling of extracellular matrices by breast cancer initiating cells.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Co | 2015 |
Outcome of children with refractory anaemia with excess of blast (RAEB) and RAEB in transformation (RAEB-T) in the Japanese MDS99 study.
Topics: Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Cell Tran | 2012 |
Polyclonal primitive hematopoietic progenitors can be detected in mobilized peripheral blood from patients with high-risk myelodysplastic syndromes.
Topics: Adult; Anemia, Refractory, with Excess of Blasts; Antigens, CD; Antigens, CD34; Antigens, Differenti | 1995 |
The role of intensive AML-specific therapy in treatment of children with RAEB and RAEB-t.
Topics: Adolescent; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocol | 1998 |
Mitoxantrone toxicity on Ehrlich ascites tumour cells: inhibition of the transplasma membrane redox activity.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cell Membrane; Cell Transformation, Neoplastic; Fe | 1991 |
Treatment of RAEB-t with intensive chemotherapy and GM-CSF.
Topics: Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Bone Marr | 1989 |
Genetic toxicology profile of the new antineoplastic drug mitoxantrone in the mammalian test systems.
Topics: Animals; Biotransformation; Cell Transformation, Neoplastic; DNA; DNA Repair; Genes, Dominant; Genes | 1986 |
Effects of amsacrine and other DNA-intercalating drugs on nuclear and nucleolar structure in cultured V79 Chinese hamster cells and PtK2 rat kangaroo cells.
Topics: Aminacrine; Aminoacridines; Amsacrine; Animals; Anthraquinones; Cell Nucleolus; Cell Nucleus; Cell S | 1985 |