mitoxantrone has been researched along with Carcinoma, Adenoid Cystic in 5 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
Carcinoma, Adenoid Cystic: Carcinoma characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells. When the cylinders occur within masses of epithelial cells, they give the tissue a perforated, sievelike, or cribriform appearance. Such tumors occur in the mammary glands, the mucous glands of the upper and lower respiratory tract, and the salivary glands. They are malignant but slow-growing, and tend to spread locally via the nerves. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leukopenia was mild, moderate, severe (1,000-1,999/mm3), and life-threatening (less than 1,000/mm3) in 17%, 23%, 42%, and 2% of courses, respectively." | 1.28 | Phase II trial of mitoxantrone in head and neck carcinoma. ( Ardalan, B; Benedetto, P; Desai, P; Feun, LG; Hussein, AM; Richman, SP; Savaraj, N; Sridhar, KS; Waldman, SM, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, JW | 1 |
| Qiu, WL | 1 |
| He, RG | 1 |
| Verweij, J | 1 |
| de Mulder, PH | 1 |
| de Graeff, A | 1 |
| Vermorken, JB | 1 |
| Wildiers, J | 1 |
| Kerger, J | 1 |
| Schornagel, J | 1 |
| Cognetti, F | 1 |
| Kirkpatrick, A | 1 |
| Sahmoud, T | 1 |
| Lefebvre, JL | 1 |
| Sridhar, KS | 1 |
| Hussein, AM | 1 |
| Benedetto, P | 1 |
| Waldman, SM | 1 |
| Feun, LG | 1 |
| Savaraj, N | 1 |
| Richman, SP | 1 |
| Ardalan, B | 1 |
| Desai, P | 1 |
| Mattox, DE | 1 |
| Von Hoff, DD | 2 |
| Balcerzak, SP | 1 |
| Shenkenberg, TD | 1 |
2 trials available for mitoxantrone and Carcinoma, Adenoid Cystic
| Article | Year |
|---|---|
Phase II study on mitoxantrone in adenoid cystic carcinomas of the head and neck. EORTC Head and Neck Cancer Cooperative Group.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Adenoid Cystic; Confidence Intervals; Disease-Free Su | 1996 |
Southwest Oncology Group study of mitoxantrone for treatment of patients with advanced adenoid cystic carcinoma of the head and neck.
Topics: Adult; Aged; Carcinoma, Adenoid Cystic; Head and Neck Neoplasms; Humans; Male; Middle Aged; Mitoxant | 1990 |
3 other studies available for mitoxantrone and Carcinoma, Adenoid Cystic
| Article | Year |
|---|---|
[Verapamil enhancement of antitumor effect of mitoxantrone on ACC-2 cell line in vitro and in vivo].
Topics: Animals; Carcinoma, Adenoid Cystic; DNA, Neoplasm; Drug Synergism; Female; Humans; Male; Mice; Mice, | 1994 |
Phase II trial of mitoxantrone in head and neck carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Dose-Response R | 1991 |
Possible mitoxantrone-induced amenorrhea.
Topics: Adult; Amenorrhea; Anthraquinones; Carcinoma, Adenoid Cystic; Estradiol; Female; Follicle Stimulatin | 1986 |