Page last updated: 2024-10-31

mitoxantrone and Canine Diseases

mitoxantrone has been researched along with Canine Diseases in 20 studies

Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.

Research Excerpts

ExcerptRelevanceReference
"Forty-four dogs with multicentric lymphoma were treated using a cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP) induction protocol or treated using a cyclophosphamide, mitoxantrone, vincristine, and prednisolone (CMOP) induction protocol."9.22Comparison of efficacy and toxicity of doxorubicin and mitoxantrone in combination chemotherapy for canine lymphoma. ( Lee, JJ; Liao, AT; Wang, SL, 2016)
"Mitoxantrone was administered to 74 dogs with lymphoma at a dosage of 5."9.07Evaluation of mitoxantrone for the treatment of lymphoma in dogs. ( Cotter, SM; Dennis, RA; Getzy, DM; L'Heureux, DA; Moore, AS; Ogilvie, GK; Rand, WS; Ruslander, D, 1994)
"Forty-four dogs with multicentric lymphoma were treated using a cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP) induction protocol or treated using a cyclophosphamide, mitoxantrone, vincristine, and prednisolone (CMOP) induction protocol."5.22Comparison of efficacy and toxicity of doxorubicin and mitoxantrone in combination chemotherapy for canine lymphoma. ( Lee, JJ; Liao, AT; Wang, SL, 2016)
"Mitoxantrone was administered to 74 dogs with lymphoma at a dosage of 5."5.07Evaluation of mitoxantrone for the treatment of lymphoma in dogs. ( Cotter, SM; Dennis, RA; Getzy, DM; L'Heureux, DA; Moore, AS; Ogilvie, GK; Rand, WS; Ruslander, D, 1994)
"Reported response rates of transitional cell carcinoma (TCC) in dogs to piroxicam in combination with either mitoxantrone or carboplatin are similar; however, it is unknown whether either drug might provide superior duration of response."2.80Randomized phase III trial of piroxicam in combination with mitoxantrone or carboplatin for first-line treatment of urogenital tract transitional cell carcinoma in dogs. ( Allstadt, SD; Boostrom, B; Rebhun, RB; Rodriguez, CO; Skorupski, KA, 2015)
" Ten dogs were given mitoxantrone at a dosage of 5."2.67Toxicoses associated with the administration of mitoxantrone to dogs with malignant tumors: a dose escalation study. ( Atwater, SW; Bergman, PJ; Chen, C; Ciekot, PA; Moore, AS; Ogilvie, GK; Walters, LM, 1994)
" Dogs underwent laser ablation of the primary tumor and were treated with mitoxantrone at a dosage of 5 mg/m2)every 3 weeks for 4 treatments."1.33Evaluation of carbon dioxide laser ablation combined with mitoxantrone and piroxicam treatment in dogs with transitional cell carcinoma. ( Payton, ME; Tangner, CH; Upton, ML, 2006)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (30.00)18.2507
2000's2 (10.00)29.6817
2010's9 (45.00)24.3611
2020's3 (15.00)2.80

Authors

AuthorsStudies
Gedon, J1
Kehl, A1
Aupperle-Lellbach, H1
von Bomhard, W1
Schmidt, JM1
Clerc-Renaud, B1
Gieger, TL1
LaRue, SM1
Nolan, MW1
Inkol, JM1
Hocker, SE1
Mutsaers, AJ1
Kishimoto, TE1
Yashima, S1
Nakahira, R1
Onozawa, E1
Azakami, D1
Ujike, M1
Ochiai, K1
Ishiwata, T1
Takahashi, K1
Michishita, M1
Marquardt, TM1
Lindley, SES1
Smith, AN1
Cannon, CM1
Rodriguez, CO2
Thamm, DH1
Childress, MO1
Northrup, NC1
Kirsch, M1
Weisse, C1
Berent, A1
Clifford, C1
Leibman, N1
Wittenburg, L1
Solomon, SB1
Lamb, K1
Allstadt, SD1
Boostrom, B1
Rebhun, RB1
Skorupski, KA1
Wang, SL1
Lee, JJ1
Liao, AT1
Arenas, C1
Peña, L2
Granados-Soler, JL1
Pérez-Alenza, MD2
Clemente, M1
De Andrés, PJ1
Daters, AT1
Mauldin, GE1
Mauldin, GN1
Brodsky, EM1
Post, GS1
Spugnini, EP1
Fanciulli, M1
Citro, G1
Baldi, A1
Sicotte, V1
Benamou, J1
Fifle, LC1
Planté, J1
Lacoste, HI1
Joly, H1
Stern, AW1
Upton, ML1
Tangner, CH1
Payton, ME1
Ogilvie, GK5
Moore, AS4
Chen, C1
Ciekot, PA1
Atwater, SW1
Bergman, PJ1
Walters, LM2
Ruslander, D1
Rand, WS1
Cotter, SM1
Getzy, DM1
L'Heureux, DA1
Dennis, RA1
Uno, Y1
Momoi, Y1
Watari, T1
Goitsuka, R1
Tsujimoto, H1
Shimada, T1
Ono, K1
Goto, N1
Hasegawa, A1
Straw, RC3
Jameson, VJ1
Lafferty, MH1
Powers, BE1
Withrow, SJ3
Obradovich, JE2
Elmslie, RE2
Vail, DM2
Curtis, CR1
Dickinson, K2
Cooper, MF2

Reviews

1 review available for mitoxantrone and Canine Diseases

ArticleYear
Preclinical models in electrochemotherapy: the role of veterinary patients.
    Future oncology (London, England), 2012, Volume: 8, Issue:7

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma

2012

Trials

6 trials available for mitoxantrone and Canine Diseases

ArticleYear
Pilot study comparing serum chemotherapy levels after intra-arterial and intravenous administration in dogs with naturally occurring urinary tract tumors.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2019, Volume: 83, Issue:3

    Topics: Animals; Antineoplastic Agents; Area Under Curve; Carboplatin; Dog Diseases; Dogs; Female; Injection

2019
Randomized phase III trial of piroxicam in combination with mitoxantrone or carboplatin for first-line treatment of urogenital tract transitional cell carcinoma in dogs.
    Journal of veterinary internal medicine, 2015, Volume: 29, Issue:1

    Topics: Animals; Antineoplastic Agents; Carboplatin; Carcinoma, Transitional Cell; Dog Diseases; Dogs; Drug

2015
Comparison of efficacy and toxicity of doxorubicin and mitoxantrone in combination chemotherapy for canine lymphoma.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2016, Volume: 57, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dog Diseases; Dogs; Doxor

2016
Evaluation of a multidrug chemotherapy protocol with mitoxantrone based maintenance (CHOP-MA) for the treatment of canine lymphoma.
    Veterinary and comparative oncology, 2010, Volume: 8, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Dog Disease

2010
Toxicoses associated with the administration of mitoxantrone to dogs with malignant tumors: a dose escalation study.
    Journal of the American Veterinary Medical Association, 1994, Aug-15, Volume: 205, Issue:4

    Topics: Animals; Bone Marrow; Diarrhea; Dog Diseases; Dogs; Female; Follow-Up Studies; Leukocyte Count; Logi

1994
Evaluation of mitoxantrone for the treatment of lymphoma in dogs.
    Journal of the American Veterinary Medical Association, 1994, Jun-15, Volume: 204, Issue:12

    Topics: Animals; Dog Diseases; Dogs; Female; Lymphoma; Male; Mitoxantrone; Remission Induction

1994

Other Studies

13 other studies available for mitoxantrone and Canine Diseases

ArticleYear
BRAF mutation status and its prognostic significance in 79 canine urothelial carcinomas: A retrospective study (2006-2019).
    Veterinary and comparative oncology, 2022, Volume: 20, Issue:2

    Topics: Animals; Carcinoma, Transitional Cell; Chlorambucil; Dog Diseases; Dogs; Female; Male; Meloxicam; Mi

2022
Treatment of genitourinary carcinoma in dogs using nonsteroidal anti-inflammatory drugs, mitoxantrone, and radiation therapy: A retrospective study.
    Journal of veterinary internal medicine, 2021, Volume: 35, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma; Dog Diseases;

2021
Combination therapy with cannabidiol and chemotherapeutics in canine urothelial carcinoma cells.
    PloS one, 2021, Volume: 16, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antineoplastic Combined Chemother

2021
Identification of tumor-initiating cells derived from two canine rhabdomyosarcoma cell lines.
    The Journal of veterinary medical science, 2017, Jul-07, Volume: 79, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Dog Diseases; Dogs; Doxorubicin; Drug Resistance,

2017
Substitution of mitoxantrone for doxorubicin in a multidrug chemotherapeutic protocol for first-line treatment of dogs with multicentric intermediate- to large-cell lymphoma.
    Journal of the American Veterinary Medical Association, 2019, Jan-15, Volume: 254, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dog Diseases; Dogs; Doxor

2019
Adjuvant therapy for highly malignant canine mammary tumours: Cox-2 inhibitor versus chemotherapy: a case-control prospective study.
    The Veterinary record, 2016, Jul-30, Volume: 179, Issue:5

    Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Case-Control Studies; Chemotherapy, Adjuvant; Cyclo

2016
Survival time of dogs with inflammatory mammary cancer treated with palliative therapy alone or palliative therapy plus chemotherapy.
    The Veterinary record, 2009, Jul-18, Volume: 165, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Breast Neoplasms; D

2009
Use of surgery and mitoxantrone chemotherapy in a dog with disseminated lymphangiosarcoma.
    Journal of the American Veterinary Medical Association, 2012, Dec-15, Volume: 241, Issue:12

    Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Lymphangiosarcoma; Male; Mitoxantrone

2012
Evaluation of carbon dioxide laser ablation combined with mitoxantrone and piroxicam treatment in dogs with transitional cell carcinoma.
    Journal of the American Veterinary Medical Association, 2006, Feb-15, Volume: 228, Issue:4

    Topics: Animals; Antineoplastic Agents; Carbon Dioxide; Carcinoma, Transitional Cell; Combined Modality Ther

2006
Malignant histiocytosis with multiple skin lesions in a dog.
    The Journal of veterinary medical science, 1993, Volume: 55, Issue:6

    Topics: Animals; Antigens, Neoplasm; Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Cycl

1993
Evaluation of single-agent chemotherapy for treatment of clinically evident osteosarcoma metastases in dogs: 45 cases (1987-1991).
    Journal of the American Veterinary Medical Association, 1993, Jan-15, Volume: 202, Issue:2

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Dog Diseases; Dog

1993
Toxicoses associated with administration of mitoxantrone to dogs with malignant tumors.
    Journal of the American Veterinary Medical Association, 1991, May-01, Volume: 198, Issue:9

    Topics: Animals; Anorexia; Bone Marrow; Diarrhea; Dog Diseases; Dogs; Female; Lymphoma; Male; Mitoxantrone;

1991
Efficacy of mitoxantrone against various neoplasms in dogs.
    Journal of the American Veterinary Medical Association, 1991, May-01, Volume: 198, Issue:9

    Topics: Animals; Carcinoma; Dog Diseases; Dogs; Lymphoma; Mitoxantrone; Neoplasms; Prospective Studies; Remi

1991