mitoxantrone has been researched along with Cancer of Liver in 79 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 18 (22.78) | 18.7374 |
1990's | 29 (36.71) | 18.2507 |
2000's | 18 (22.78) | 29.6817 |
2010's | 11 (13.92) | 24.3611 |
2020's | 3 (3.80) | 2.80 |
Authors | Studies |
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Hong, C; Li, Q; Luo, W; Su, Y; Wang, C; Wang, Y; Xie, S; Zhai, Y; Zhang, X; Zhao, J; Zhu, Z | 1 |
Guo, G; He, X; Li, J; Lin, Y; Liu, J; Xie, B; Zhang, X | 1 |
Czauderna, C; Galle, PR; Heil, E; Heinrich, B; Heinrich, S; Kloeckner, R; Koch, S; Marquardt, JU; Philippe P Diggs, L; Schmidtmann, I; Sprinzl, M; Weinmann, A; Wörns, MA | 1 |
Jia, M; Shao, L; Ye, Q | 1 |
Arai, Y; Furuse, J; Ikeda, M; Inaba, Y; Kobayashi, T; Mitsunaga, S; Morizane, C; Okusaka, T; Sato, Y; Ueno, H | 1 |
Guo, Y; Hu, Y; Huang, Y; Liu, D; Lu, B; Wang, X; Zhu, Z | 1 |
An, Y; Ding, Y; Han, Y; He, C; Jia, G; Tang, Q; Wang, X | 1 |
Kunda, NM; Maker, AV; Prabhakar, BS; Qiao, G; Qin, J; Tulla, K | 1 |
Chakraborty, G; Gorain, M; Kumar, D; Kumar, S; Kundu, GC; Sharma, P | 1 |
Di Pietro, A; Guterres, FA; Martinez, GR; Rocha, ME; Scoparo, CT; Valdameri, G; Winnischofer, SM; Worfel, PR | 1 |
Hagihara, A; Ikeda, M; Iwasa, S; Kojima, Y; Morizane, C; Okusaka, T; Ueno, H | 1 |
Liu, J; Sun, X; Zeng, L; Zhang, Z; Zhou, Q | 1 |
Furuse, J; Ikeda, M; Ishii, H; Mitsunaga, S; Morizane, C; Nakachi, K; Okusaka, T; Suzuki, E; Ueno, H | 1 |
Chen, HC; Hsu, CL; Hung, CF; Lin, CC; Pan, KT; Sung, CM; Tseng, JH; Yeh, CT | 1 |
Liang, KH; Lin, CC; Yeh, CT | 1 |
Fan, R; Gan, Y; Guo, S; Li, F; Yu, M; Zhang, X; Zhu, C | 1 |
Andreesen, R; Bodenstein, H; Clemens, M; Fehnle, K; Fischer, JT; Heidemann, E; Hirschmann, WD; Kaufmann, M; König, M; Mahlke, M; Oberhoff, C; Scharl, A; Schulze, M; Souchon, R; Stoeger, H | 1 |
Chang, HK; Chang, WC; Chen, JS; Liau, CT; Lin, YC; Yang, TS | 1 |
Ikeda, M; Okusaka, T; Ueno, H | 1 |
Ikeda, M; Morizane, C; Okusaka, T; Takezako, Y; Ueno, H | 1 |
Allen, K; Barth, NM; Beutel, LD; Chico, S; Dillman, RO; VanderMolen, LA | 1 |
Akimoto, M; Ebara, M; Fukuda, H; Kondo, F; Saisho, H; Sato, T; Yoshikawa, M | 1 |
Enoki, T; Hamano, K; Harada, E; Kitada, K; Noshima, S | 1 |
Deguchi, K; Hamaguchi, J; Kamiyama, N; Kamiyama, T; Kudo, T; Nakagawa, H; Nakagawa, T; Nakanishi, K; Nishimura, S; Takahashi, M; Todo, S; Yokoo, H | 1 |
Aravantinos, G; Bafaloukos, D; Fountzilas, G; Gogas, H; Kalofonos, HP; Koutras, A; Makatsoris, T; Mantzourani, M; Markopoulos, C; Onyenadum, A; Tzorakoelefterakis, E; Xiros, N | 1 |
Dittrich, C; Dudczak, R; Lenzhofer, R; Moser, K; Pirker, P; Rainer, H; Schuster, R | 1 |
Coetzer, BJ; Falkson, G; Terblanche, AP | 1 |
Bedikian, AY; Bodey, GP; Karlin, D; Korinek, J; Stroehlein, J; Valdivieso, M | 1 |
Hirayama, R; Ichikawa, W; Kawachi, Y; Mishima, Y; Miyanaga, T; Nihei, Z; Osanai, T; Sawai, S; Togo, S; Yamashita, T | 1 |
Asaumi, S; Iino, Y; Ishikawa, H; Iwanami, K; Kawashima, K; Kobayashi, J; Kubota, K; Matsumoto, H; Morishita, Y; Yokoe, T | 1 |
Hou, SX; Liao, GT; Zhang, ZR | 1 |
Harima, K; Kawa, S; Murata, T; Nagata, K; Nishida, T; Okuda, M; Oshima, T; Seki, Y; Tanaka, Y; Uda, M | 1 |
Bai, S; Hou, S; Liao, G; Zhang, X; Zhang, Z | 1 |
Bai, S; Hou, S; Liao, G; Xie, C; Zhang, X; Zhang, Z | 1 |
Cherqui, D; Dhumeaux, D; Duvoux, C; Fagniez, PL; Julien, M; LeBourgeois, JP; Piedbois, P; Pierga, JY; Tran Van-Nhieu, J; Vavasseur, D | 1 |
Blanz, J; Ehninger, G; Gebhardt, R; Mewes, K; Zeller, KP | 1 |
Audisio, R; Bajetta, E; Bartoli, C; Bochicchio, AM; Bonfanti, G; Buzzoni, R; Colleoni, M; Nolè, F | 1 |
Abbruzzese, J; Ajani, JA; Carrasco, CH; Charnsangavej, C; Jones, DV; Levin, B; Patt, YZ; Wallace, S | 1 |
Aoyagi, H; Horiguchi, J; Iino, Y; Ishida, T; Maemura, M; Morishita, Y; Sugamata, N; Takai, Y; Yokoe, T | 1 |
Brambs, HJ; Brensing, KA; Görich, J; Kunze, V; Müller-Miny, H; Rilinger, N; Sokiranski, R | 1 |
Beger, HG; Leder, G; Link, KH; Pillasch, J; Weindel, M | 1 |
Hiraki, S; Maeda, Y; Nakashima, K; Nishida, M; Oka, M; Suzuki, T; Takao, K; Takao, T | 1 |
Colleoni, M; Liessi, G; Manente, P; Mastrapasqua, G; Nelli, P; Pancheri, F; Sgarbossa, G; Vicario, G | 1 |
Beger, HG; Butzer, U; Danenberg, KD; Danenberg, PV; Kornmann, M; Leder, GH; Lenz, HJ; Link, KH; Metzger, R; Pillasch, J; Safi, F; Weindel, M | 1 |
Hasegawa, M; Koyama, T; Manabe, K; Takagi, K | 1 |
Akagi, K; Kimura, H; Murata, T; Nagata, K; Nasu, R; Tanaka, Y; Uokawa, K | 1 |
Beger, HG; Butzer, U; Gansauge, F; Kornmann, M; Leder, GH; Link, KH; Pillasch, J; Staib, L | 1 |
Beger, HG; Kornmann, M; Leder, G; Link, KH; Pillasch, AF; Pressmar, J; Schatz, M; Sunelaitis, E | 1 |
Fujitake, S; Kataoka, S; Maeda, Y; Nozaki, H; Shimizu, M; Tohyama, M | 1 |
Bashey, A; Corringham, RE; Corringham, S; Garrett, J; Gilpin, EA; Ho, AD; Lane, TA; Law, P | 1 |
Fujii, S; Fukushi, Y; Futagami, M; Higuchi, T; Saito, Y; Sakamoto, T; Sato, S; Takami, H; Yokoyama, Y | 1 |
Beger, HG; Butzer, U; Danenberg, KD; Danenberg, PV; Kornmann, M; Leder, G; Link, KH; Pillasch, J; Salonga, D; Sunelaitis, E | 1 |
Dorey, F; Eilber, FC; Eilber, FR; Forscher, C; Nelson, SD; Rosen, G | 1 |
Carlson, LE; Glück, S; Koski, T | 1 |
Beger, HG; Formentini, A; Gansauge, F; Kornmann, M; Leder, G; Link, KH; Pillasch, J; Schatz, M; Staib, L; Sunelaitis, E | 1 |
Auerbach, M; Elias, EG; Orford, J | 1 |
Bajetta, E; Colleoni, M; de Braud, F; Di Bartolomeo, M; Nole, F | 1 |
Hirayama, R; Ichikawa, W; Kawachi, Y; Mishima, Y; Nihei, Z; Sawai, S; Tamaru, H; Uetake, H; Yamashita, T | 1 |
Charlotte, F; Cherqui, D; Duvoux, C; Julien, M; Lauzet, JY; Le Péchoux, C; Mathieu, D; Métreau, JM; Piedbois, P; Rotman, N | 1 |
Aoki, K; Nose, H; Okada, S; Okazaki, N; Yoshimori, M | 1 |
Pestalozzi, B; Sauter, C; Schwendener, R | 1 |
Moriyama, N; Okada, S; Okazaki, N; Shimada, Y; Takayasu, K; Yoshida, T; Yoshino, M | 1 |
Du, MQ; Hutchinson, WL; Johnson, PJ; Williams, R | 1 |
Hartlapp, J; Heidemann, E; Hossfeld, D; Kunz, S; Neeser, E; Possinger, K; Schumacher, K; Steinke, B; von Ingersleben, G; Waldmann, R | 1 |
Lai, KH; Lee, SD; Lin, HC; Lin, HJ; Lo, GH; Ng, WW; Tam, TN; Teng, HC; Tsai, YT; Wu, JC | 1 |
Duthie, SJ; Grant, MH | 2 |
Coleman, RE; O'Reilly, SM; Rubens, RD | 1 |
Callender, ME; Clarke, R; Dickey, W; Johnston, GW; McAleer, JJ | 1 |
Carbone, PP; Coetzer, BJ; Creech, RH; Falkson, G; Johnson, LA; Ryan, LM; Schutt, AJ; Simson, IW | 1 |
Miyamoto, K; Ohkura, H; Okazaki, N; Shimada, Y; Yoshida, T; Yoshino, M | 1 |
Brook, MG; Dunk, AA; Goh, C; Lever, AM; McDonald, JA; Thomas, HC | 1 |
Dunk, AA; Johnson, PJ; Lok, AS; Melia, W; Murray-Lyon, I; Scott, SC; Thomas, HC; Williams, R | 1 |
Blackstein, ME; Evans, WK; Fine, S; Habal, F; Heathcote, J; Kutas, G; Langer, B; Pritchard, KI; Shepherd, FA; Taylor, B | 1 |
Bai, SH; Chen, XH; Tang, P; Xu, G | 1 |
Berkarda, B; Büyükünal, E; Derman, U; Serdengecti, S | 1 |
Davis, RB; Henderson, ES; Leone, LA; Van Echo, DA | 1 |
Coetzer, BJ; Falkson, G | 1 |
3 review(s) available for mitoxantrone and Cancer of Liver
Article | Year |
---|---|
[Chemotherapy for hepatocellular carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Clinical Trials as Topic; Doxorubicin; Drug Administration Schedule; Fluorouracil; Humans; Liver Neoplasms; Mitoxantrone; Survival Rate; Tamoxifen | 2004 |
Mitoxantrone, 5-FU + folinic acid, mitomycin C for regional chemotherapy of malignant liver tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Mitomycin; Mitoxantrone | 1996 |
Basic research supported developments of chemotherapy in nonresectable isolated colorectal liver metastases to a protocol of hepatic artery infusion using mitoxantrone, 5-FU + folinic acid and mitomycin C.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal Neoplasms; Drug Administration Schedule; Female; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Middle Aged; Mitomycin; Mitoxantrone; Randomized Controlled Trials as Topic; Survival Analysis | 1999 |
21 trial(s) available for mitoxantrone and Cancer of Liver
Article | Year |
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A Phase I/II trial of continuous hepatic intra-arterial infusion of 5-fluorouracil, mitoxantrone and cisplatin for advanced hepatocellular carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Catheters; Cisplatin; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Mitoxantrone; Treatment Outcome | 2017 |
A randomized multicenter phase II clinical trial of mitoxantrone-loaded nanoparticles in the treatment of 108 patients with unresected hepatocellular carcinoma.
Topics: Adult; Aged; alpha-Fetoproteins; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Male; Middle Aged; Mitoxantrone; Nanomedicine; Nanoparticles; Survival Analysis; Treatment Outcome; Young Adult | 2009 |
A phase I/II study of combined chemotherapy with mitoxantrone and uracil/tegafur for advanced hepatocellular carcinoma.
Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Hepatocellular; Cohort Studies; Female; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Mitoxantrone; Neoplasm Staging; Peritoneal Neoplasms; Survival Rate; Tegafur; Treatment Outcome; Uracil | 2011 |
Is first-line single-agent mitoxantrone in the treatment of high-risk metastatic breast cancer patients as effective as combination chemotherapy? No difference in survival but higher quality of life were found in a multicenter randomized trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Germany; Humans; Liver Neoplasms; Logistic Models; Lung Neoplasms; Middle Aged; Mitoxantrone; Neoplasm Staging; Probability; Proportional Hazards Models; Quality of Life; Risk Assessment; Sensitivity and Specificity; Statistics, Nonparametric; Survival Analysis; Treatment Outcome | 2002 |
A phase II trial of continuous infusion of 5-fluorouracil, mitoxantrone, and cisplatin for metastatic hepatocellular carcinoma.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Humans; Infusions, Intravenous; Liver Neoplasms; Male; Middle Aged; Mitoxantrone; Neoplasm Metastasis | 2005 |
High-dose chemotherapy and autologous stem cell rescue for metastatic breast cancer: superior survival for tandem compared with single transplants.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carboplatin; Cohort Studies; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Liver Neoplasms; Lung Neoplasms; Middle Aged; Mitoxantrone; Organ Specificity; Peripheral Blood Stem Cell Transplantation; Retrospective Studies; Survival Analysis; Thiotepa; Transplantation, Autologous; Treatment Outcome | 2005 |
Mitoxantrone plus vinorelbine in pretreated patients with metastatic breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Female; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Middle Aged; Mitoxantrone; Remission Induction; Salvage Therapy; Skin Neoplasms; Vinblastine; Vinorelbine | 2007 |
[Clinical study on the effect of intra-arterial injection of mitoxantrone-lipiodol emulsion for hepatocellular carcinoma].
Topics: Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Female; Hepatic Artery; Humans; Injections, Intra-Arterial; Iodized Oil; Liver Neoplasms; Male; Middle Aged; Mitoxantrone | 1994 |
A phase II study of mitoxantrone combined with beta-interferon in unresectable hepatocellular carcinoma.
Topics: Adult; Aged; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Drug Administration Schedule; Feasibility Studies; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Interferon-beta; Leukopenia; Liver Neoplasms; Male; Middle Aged; Mitoxantrone; Remission Induction; Survival Rate; Thrombocytopenia | 1993 |
A phase I-II trial of mitoxantrone by hepatic arterial infusion in patients with hepatocellular carcinoma or colorectal carcinoma metastatic to the liver.
Topics: Adult; Aged; Carcinoma; Carcinoma, Hepatocellular; Colorectal Neoplasms; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Mitoxantrone | 1993 |
Intra-arterial chemotherapy followed by chemo-embolisation in unresectable hepatocellular carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Combined Modality Therapy; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Mitoxantrone; Survival Rate | 1997 |
Thymidylate synthase is a predictor for response and resistance in hepatic artery infusion chemotherapy.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Colorectal Neoplasms; Drug Administration Schedule; Drug Resistance, Neoplasm; Epirubicin; Female; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Middle Aged; Mitoxantrone; Polymerase Chain Reaction; Predictive Value of Tests; Prognosis; RNA, Messenger; Survival Rate; Thymidylate Synthase; Transcription, Genetic | 1997 |
[Effect on hepatic function of hepatic artery infusion chemotherapy using epirubicin and mitoxantrone for advanced hepatocellular carcinoma].
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Hepatocellular; Drug Administration Schedule; Epirubicin; Female; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver; Liver Neoplasms; Male; Middle Aged; Mitoxantrone | 1998 |
Regional chemotherapy directed by individual chemosensitivity testing in vitro: a prospective decision-aiding trial.
Topics: Adult; Aged; Antidotes; Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Middle Aged; Mitomycin; Mitoxantrone; Neoplastic Stem Cells; Prospective Studies; Tumor Stem Cell Assay | 1996 |
A phase II study of two cycles of high-dose chemotherapy with autologous stem cell support in patients with metastatic breast cancer who meet eligibility criteria for a single cycle.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carboplatin; Cyclophosphamide; Disease-Free Survival; Dose-Response Relationship, Drug; Etoposide; Female; Graft Survival; Hematopoietic Stem Cell Transplantation; Humans; Liver Neoplasms; Middle Aged; Mitoxantrone; Platelet Count; Soft Tissue Neoplasms; Survival Rate; Tamoxifen; Thiotepa; Transplantation, Autologous | 2000 |
Thymidylate synthase quantitation and in vitro chemosensitivity testing predicts responses and survival of patients with isolated nonresectable liver tumors receiving hepatic arterial infusion chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Epirubicin; Female; Fluorouracil; Folic Acid; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Mitomycin; Mitoxantrone; Predictive Value of Tests; Prospective Studies; Thymidylate Synthase; Treatment Outcome; Tumor Stem Cell Assay | 2000 |
Regional chemotherapy of nonresectable colorectal liver metastases with mitoxantrone, 5-fluorouracil, folinic acid, and mitomycin C may prolong survival.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Male; Middle Aged; Mitomycin; Mitoxantrone; Survival Analysis; Treatment Outcome | 2001 |
Randomized clinical trial comparing mitoxantrone with epirubicin and with doxorubicin, each combined with cyclophosphamide in the first-line treatment of patients with metastatic breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Epirubicin; Female; Humans; Liver Neoplasms; Lung Neoplasms; Middle Aged; Mitoxantrone; Quality of Life; Randomized Controlled Trials as Topic; Survival Rate | 1990 |
A random phase II study of mitoxantrone and cisplatin in patients with hepatocellular carcinoma. An ECOG study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Drug Evaluation; Female; Humans; Liver Neoplasms; Male; Middle Aged; Mitoxantrone; Prognosis; Random Allocation | 1987 |
Human lymphoblastoid interferon does not increase survival when added to mitozantrone in the treatment of hepatocellular carcinomas.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Child; Female; Humans; Interferon-alpha; Liver Neoplasms; Male; Middle Aged; Mitoxantrone | 1987 |
A clinical trial of mitoxantrone (novantrone) versus doxorubicin (adriamycin) in combination chemotherapy for metastatic breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Middle Aged; Mitoxantrone; Neoplasm Metastasis | 1987 |
55 other study(ies) available for mitoxantrone and Cancer of Liver
Article | Year |
---|---|
Synthesis and biological properties of polyamine modified flavonoids as hepatocellular carcinoma inhibitors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Aspirin; Carcinoma, Hepatocellular; Cell Line; Flavonoids; Liver Neoplasms; Neoplasm Metastasis; Polyamines | 2016 |
High-throughput screening identified mitoxantrone to induce death of hepatocellular carcinoma cells with autophagy involvement.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Death; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Hep G2 Cells; High-Throughput Screening Assays; Humans; Liver Neoplasms; Mitoxantrone; Small Molecule Libraries; Tumor Cells, Cultured | 2020 |
Validation of prognostic accuracy of MESH, HKLC, and BCLC classifications in a large German cohort of hepatocellular carcinoma patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Carcinoma, Hepatocellular; Etoposide; Female; Germany; Humans; Ifosfamide; Kaplan-Meier Estimate; Liver; Liver Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Mitoxantrone; Neoplasm Staging; Predictive Value of Tests; Prognosis; Retrospective Studies; Risk Assessment; ROC Curve; Tomography, X-Ray Computed; Young Adult | 2020 |
miR-130-3p Promotes MTX-Induced Immune Killing of Hepatocellular Carcinoma Cells by Targeting EPHB4.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Liver Neoplasms; MicroRNAs; Mitoxantrone; Receptor, EphB4; Tumor Microenvironment | 2021 |
Mycoplasma-associated multidrug resistance of hepatocarcinoma cells requires the interaction of P37 and Annexin A2.
Topics: Adaptor Proteins, Signal Transducing; Annexin A2; Anti-Bacterial Agents; Antineoplastic Agents; Azithromycin; Carcinoma, Hepatocellular; Cell Line, Tumor; Deoxycytidine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluoroquinolones; Gemcitabine; Humans; Liver Neoplasms; Mitoxantrone; Moxifloxacin; Mycoplasma hyorhinis; Protein Binding; Real-Time Polymerase Chain Reaction | 2017 |
Theranostic micelles based on upconversion nanoparticles for dual-modality imaging and photodynamic therapy in hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Delivery Systems; Epithelial Cell Adhesion Molecule; Female; Humans; Liver Neoplasms; Luminescence; Magnetic Resonance Imaging; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Mitoxantrone; Nanoparticles; Neoplasms, Experimental; Photochemotherapy; RAW 264.7 Cells; Theranostic Nanomedicine | 2018 |
Vaccination With Mitoxantrone-Treated Primary Colon Cancer Cells Enhances Tumor-Infiltrating Lymphocytes and Clinical Responses in Colorectal Liver Metastases.
Topics: Animals; Antineoplastic Agents; Cancer Vaccines; Cell Cycle Checkpoints; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Female; Humans; Liver Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Mice; Mitoxantrone; Treatment Outcome | 2019 |
Functional characterization of stromal osteopontin in melanoma progression and metastasis.
Topics: Animals; Carcinogenesis; Cell Communication; Cell Proliferation; Cell Separation; Disease Progression; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Liver Neoplasms; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Knockout; Mitoxantrone; Neoplastic Stem Cells; Neovascularization, Pathologic; Osteopontin; Phenotype; Side-Population Cells; Signal Transduction; Stromal Cells | 2013 |
Dual properties of hispidulin: antiproliferative effects on HepG2 cancer cells and selective inhibition of ABCG2 transport activity.
Topics: Animals; Antioxidants; Apoptosis; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Carcinoma, Hepatocellular; Catalase; Cell Line, Tumor; Cell Proliferation; Cell Survival; Flavones; Glutathione; HEK293 Cells; Hep G2 Cells; Humans; L Cells; Liver Neoplasms; Mice; Mitoxantrone; Multidrug Resistance-Associated Proteins; Plants, Medicinal; Reactive Oxygen Species; RNA, Messenger | 2015 |
Predictive factors of outcome and tumor response to systemic chemotherapy in patients with metastatic hepatocellular carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Mitoxantrone; Neoplasm Staging; Prognosis; Remission Induction; Survival Rate; Treatment Outcome | 2008 |
Retrospective comparison between a regular and a split-dose protocol of 5-fluorouracil, cisplatin, and mitoxantrone for the treatment of far advanced hepatocellular carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Clinical Protocols; Disease Progression; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Mitoxantrone; Retrospective Studies; Survival Analysis | 2011 |
GALNT14 SNP as a potential predictor of response to combination chemotherapy using 5-FU, mitoxantrone and cisplatin in advanced HCC.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Pharmacological; Carcinoma, Hepatocellular; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Genome-Wide Association Study; Humans; Linkage Disequilibrium; Liver Neoplasms; Male; Middle Aged; Mitoxantrone; N-Acetylgalactosaminyltransferases; Neoplasm Staging; Polymorphism, Single Nucleotide; Prospective Studies; Retrospective Studies | 2011 |
Dual-functional liposome for tumor targeting and overcoming multidrug resistance in hepatocellular carcinoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Resistance, Multiple; Humans; Liposomes; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mitoxantrone; Neoplasm Transplantation; Neoplasms; Polymers; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2012 |
Chemotherapy using 5-fluorouracil, mitoxantrone, and cisplatin for patients with advanced hepatocellular carcinoma: an analysis of 63 cases.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Mitoxantrone; Neoplasm Staging; Prognosis; Survival Analysis; Treatment Outcome | 2004 |
Relationship between therapeutic efficacy of arterial infusion chemotherapy and expression of P-glycoprotein and p53 protein in advanced hepatocellular carcinoma.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Carboplatin; Carcinoma, Hepatocellular; Epirubicin; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Immunohistochemistry; Infusions, Intra-Arterial; Liver Neoplasms; Mitoxantrone; Retrospective Studies | 2006 |
[A case of multiple lung metastases of hepatocellular carcinoma after resection of liver and tumor thrombi in the inferior vena cava responding to chemotherapy using 5-FU, mitoxantrone and CDDP].
Topics: alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Drug Administration Schedule; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Mitoxantrone; Neoplastic Cells, Circulating; Postoperative Period; Remission Induction; Vena Cava, Inferior | 2007 |
N-glycan alterations are associated with drug resistance in human hepatocellular carcinoma.
Topics: Antibiotics, Antineoplastic; Carbohydrate Sequence; Carcinoma, Hepatocellular; Down-Regulation; Drug Resistance, Neoplasm; Drug Tolerance; Epirubicin; Fucosyltransferases; Glycosylation; Glycosyltransferases; Humans; Liver Neoplasms; Mitoxantrone; N-Acetylglucosaminyltransferases; Oligosaccharides, Branched-Chain; Polysaccharides; Tumor Cells, Cultured; Up-Regulation | 2007 |
[Mitoxantrone in the primary treatment of metastasizing breast cancer].
Topics: Aged; Alopecia; Anthraquinones; Brain Neoplasms; Breast Neoplasms; Drug Tolerance; Electrocardiography; Female; Humans; Leukocyte Count; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Mitoxantrone; Skin Neoplasms; Time Factors | 1984 |
Phase II trial of mitoxantrone in patients with primary liver cancer.
Topics: Adolescent; Adult; Aged; Anthraquinones; Antineoplastic Agents; Drug Evaluation; Female; Humans; Leukopenia; Liver Neoplasms; Male; Middle Aged; Mitoxantrone | 1984 |
Phase II evaluation of dihydroxyanthracenedione (DHAD, NSC 301739) in patients with upper gastrointestinal tumors. A preliminary report.
Topics: Adult; Aged; Anthraquinones; Antineoplastic Agents; Drug Evaluation; Female; Humans; Leukocyte Count; Leukopenia; Liver Neoplasms; Male; Middle Aged; Mitoxantrone; Neoplasm Metastasis; Pancreatic Neoplasms; Platelet Count; Stomach Neoplasms; Thrombocytopenia | 1983 |
[A case of recurrent breast cancer responding to combination therapy with mitoxantrone (MIT), 5'-deoxy-5-fluorouridine (5'-DFUR) and medroxyprogesterone acetate (MPA)].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Administration Schedule; Female; Floxuridine; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver Neoplasms; Mastectomy, Radical; Medroxyprogesterone Acetate; Middle Aged; Mitoxantrone; Ovariectomy | 1994 |
[Study on mitoxantrone polycyanoacrylate nanospheres].
Topics: Animals; Cyanoacrylates; Drug Carriers; Humans; Liver Neoplasms; Mice; Mice, Nude; Microspheres; Mitoxantrone; Neoplasm Transplantation | 1994 |
[Clinical study of cyclic intra-arterial chemotherapy using mitoxantrone for advanced hepatocellular carcinoma].
Topics: Aged; Carcinoma, Hepatocellular; Drug Administration Schedule; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Mitoxantrone | 1994 |
[An observation of the anticarcinogenic effect of mitoxantrone-polybutylcyanoacrylate-nanosperes].
Topics: Animals; Carcinoma, Hepatocellular; Drug Carriers; Drug Delivery Systems; Enbucrilate; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Microspheres; Mitoxantrone; Neoplasm Transplantation | 1993 |
[A model of orthotopic transplantation of human hepatoma established in nude mice tumor inhibition studies].
Topics: Animals; Disease Models, Animal; Drug Delivery Systems; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Mitoxantrone; Neoplasm Transplantation | 1993 |
Multimodal adjuvant treatment and liver transplantation for advanced hepatocellular carcinoma. A pilot study.
Topics: Adult; Carcinoma, Hepatocellular; Combined Modality Therapy; Embolization, Therapeutic; Female; Follow-Up Studies; Humans; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Neoplasm Staging; Pilot Projects | 1994 |
Cytochrome P-450-induced cytotoxicity of mitoxantrone by formation of electrophilic intermediates.
Topics: Animals; Bile; Biotransformation; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Humans; Kinetics; Liver; Liver Neoplasms; Male; Mass Spectrometry; Mitoxantrone; Molecular Structure; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 1993 |
[Combined mitoxantrone therapy for heavily pretreated metastatic breast cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Doxorubicin; Epirubicin; Female; Humans; Liver Neoplasms; Middle Aged; Mitoxantrone; Salvage Therapy; Skin Neoplasms | 1993 |
[Percutaneous drainage of refractory necrotizing tumors: experience in 9 patients].
Topics: Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Cystadenocarcinoma; Drainage; Female; Histiocytoma, Benign Fibrous; Humans; Leiomyosarcoma; Liver Neoplasms; Lymphoma, Non-Hodgkin; Male; Middle Aged; Mitoxantrone; Necrosis; Neoplasm Recurrence, Local; Neoplasms; Pancreatic Neoplasms; Rectal Neoplasms; Sclerotherapy; Tomography, X-Ray Computed; Uterine Cervical Neoplasms; Uterine Neoplasms | 1995 |
[Effects of intra-hepatic arterial injection of mitoxantrone for hepatocellular carcinoma].
Topics: Adult; Aged; Antineoplastic Agents; Bone Marrow; Carcinoma, Hepatocellular; Drug Administration Schedule; Hepatic Artery; Humans; Injections, Intra-Arterial; Liver Neoplasms; Middle Aged; Mitoxantrone | 1996 |
[The effect of hepatic arterial infusion chemotherapy on the prognosis after hepatectomy for hepatocellular carcinoma].
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Hepatocellular; Doxorubicin; Embolization, Therapeutic; Female; Hepatectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Iodized Oil; Liver Neoplasms; Male; Middle Aged; Mitoxantrone; Prognosis; Retrospective Studies | 1998 |
[A case of breast cancer with liver metastases responding remarkably to combination therapy of mitoxantrone (MIT), doxifluridine (5'-DFUR) and medroxyprogesterone acetate (MPA)].
Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Resistance, Neoplasm; Epirubicin; Female; Floxuridine; Fluorouracil; Humans; Liver Neoplasms; Medroxyprogesterone Acetate; Middle Aged; Mitoxantrone; Tamoxifen | 1999 |
Secondary acute nonlymphocytic leukemia following successful chemotherapy combining cisplatin, doxorubicin, and cyclophosphamide for stage IV epithelial ovarian cancer.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow; Cisplatin; Cyclophosphamide; Cystadenocarcinoma, Mucinous; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Liver Neoplasms; Middle Aged; Mitoxantrone; Ovarian Neoplasms; Prednisolone; Remission Induction; Reoperation | 2000 |
Recurrent gastrointestinal stromal sarcomas.
Topics: Antineoplastic Agents; Chemotherapy, Adjuvant; Female; Gastrointestinal Neoplasms; Humans; Injections, Intraperitoneal; Liver Neoplasms; Male; Mitoxantrone; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Retrospective Studies; Sarcoma; Survival Rate; Treatment Outcome | 2000 |
Longitudinal effects of high-dose chemotherapy and autologous stem cell transplantation on quality of life in the treatment of metastatic breast cancer.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Anxiety; Arthralgia; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Depression; Female; Hematopoietic Stem Cell Transplantation; Humans; Liver Neoplasms; Longitudinal Studies; Lung Neoplasms; Middle Aged; Mitoxantrone; Paclitaxel; Quality of Life; Surveys and Questionnaires; Time Factors; Transplantation, Autologous | 2001 |
Experience with methotrexate, 5-fluorouracil, and leucovorin (MFL): a first line effective, minimally toxic regimen for metastatic breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Disease-Free Survival; Female; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Middle Aged; Mitoxantrone; Prospective Studies | 2002 |
Mitoxantrone in patients affected by hepatocellular carcinoma with unfavorable prognostic factors.
Topics: Aged; Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Male; Middle Aged; Mitoxantrone; Prognosis | 1992 |
[Successful preparation of mitoxantrone emulsion containing non-ionic contrast medium].
Topics: Carcinoma, Hepatocellular; Delayed-Action Preparations; Drug Therapy, Combination; Emulsions; Humans; Iodized Oil; Iohexol; Liver Neoplasms; Male; Middle Aged; Mitoxantrone | 1992 |
[Liver transplantation associated with combined adjuvant treatment in hepatocellular carcinoma. Feasibility and preliminary results].
Topics: Adult; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Doxorubicin; Embolization, Therapeutic; Female; Humans; Iodized Oil; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Mitoxantrone; Postoperative Care; Preoperative Care; Prospective Studies | 1992 |
Prognostic factors in patients with hepatocellular carcinoma receiving systemic chemotherapy.
Topics: alpha-Fetoproteins; Analysis of Variance; Antineoplastic Agents; Ascites; Bilirubin; Carcinoma, Hepatocellular; Cisplatin; Doxorubicin; Etoposide; Female; Fluorouracil; Follow-Up Studies; Humans; Interferon-gamma; Liver Neoplasms; Male; Middle Aged; Mitoxantrone; Multivariate Analysis; Prognosis; Regression Analysis; Risk Factors; Serum Albumin; Tegafur; Time Factors | 1992 |
Phase I/II study of liposome-complexed mitoxantrone in patients with advanced breast cancer.
Topics: Adenocarcinoma; Agranulocytosis; Breast Neoplasms; Dose-Response Relationship, Drug; Drug Carriers; Drug Evaluation; Female; Humans; Liposomes; Liver Neoplasms; Mitoxantrone | 1992 |
Changes in mode of response to chemotherapy for hepatocellular carcinoma induced by transarterial embolization. A case report.
Topics: Carcinoma, Hepatocellular; Combined Modality Therapy; Embolization, Therapeutic; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Mitoxantrone; Remission Induction; Tomography, X-Ray Computed | 1991 |
Serum and tissue alpha-L-fucosidase activity in the pre-clinical and clinical stages of hepatocellular carcinoma.
Topics: Adult; Aged; alpha-Fetoproteins; alpha-L-Fucosidase; Carcinoma, Hepatocellular; Doxorubicin; Female; Glycoside Hydrolases; Humans; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Mitoxantrone | 1991 |
Phase II study of mitoxantrone in unresectable primary hepatocellular carcinoma following hepatitis B infection.
Topics: Adult; Aged; Carcinoma, Hepatocellular; Drug Evaluation; Female; Hepatitis B; Humans; Liver Neoplasms; Male; Middle Aged; Mitoxantrone | 1989 |
The toxicity of menadione and mitozantrone in human liver-derived Hep G2 hepatoma cells.
Topics: Adult; Biotransformation; Carcinoma, Hepatocellular; Cell Survival; Epoxide Hydrolases; Glutathione; Glutathione Transferase; Humans; Inactivation, Metabolic; Liver Neoplasms; Mitoxantrone; Oxidation-Reduction; Oxidoreductases; Tumor Cells, Cultured; Vitamin K | 1989 |
The role of reductive and oxidative metabolism in the toxicity of mitoxantrone, adriamycin and menadione in human liver derived Hep G2 hepatoma cells.
Topics: Carcinoma, Hepatocellular; Doxorubicin; Humans; Liver Neoplasms; Mitoxantrone; Oxidation-Reduction; Tumor Cells, Cultured; Vitamin K | 1989 |
Phase II study of mitoxantrone for liver metastases from breast cancer.
Topics: Bone Marrow; Breast Neoplasms; Depression, Chemical; Drug Evaluation; Female; Humans; Infusions, Intravenous; Liver Neoplasms; Mitoxantrone; Time Factors | 1989 |
Regional lipiodolized chemotherapy for cholangiocarcinoma associated with oral contraceptives.
Topics: Adenoma, Bile Duct; Adult; Antineoplastic Combined Chemotherapy Protocols; Common Bile Duct Neoplasms; Contraceptives, Oral, Combined; Diatrizoate; Diatrizoate Meglumine; Doxorubicin; Female; Humans; Injections, Intra-Arterial; Iodized Oil; Liver Neoplasms; Mitoxantrone | 1987 |
Phase II trial of mitoxantrone in patients with hepatocellular carcinoma.
Topics: Aged; Carcinoma, Hepatocellular; Drug Evaluation; Female; Humans; Leukopenia; Liver Neoplasms; Male; Middle Aged; Mitoxantrone; Thrombocytopenia | 1988 |
Mitozantrone as single agent therapy in hepatocellular carcinoma. A phase II study.
Topics: Adult; Aged; Anthraquinones; Carcinoma, Hepatocellular; Child; Drug Evaluation; Female; Heart Diseases; Humans; Leukopenia; Liver Neoplasms; Male; Middle Aged; Mitoxantrone; Thrombocytopenia | 1985 |
Hepatic arterial infusion of mitoxantrone in the treatment of primary hepatocellular carcinoma.
Topics: Adult; Aged; Carcinoma, Hepatocellular; Doxorubicin; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Mitoxantrone | 1987 |
[A study of antineoplastic activity of DHAQ on human adenocarcinoma cells of lung hepatoma and gastric cancer cells in vitro].
Topics: Adenocarcinoma; Carcinoma, Hepatocellular; Cell Line; Humans; Liver Neoplasms; Lung Neoplasms; Mitotic Index; Mitoxantrone; Stomach Neoplasms; Tumor Stem Cell Assay | 1986 |
Phase II trial of mitoxantrone in advanced primary liver cancer: a Cancer and Leukemia Group B Study.
Topics: Adolescent; Adult; Aged; Anthraquinones; Drug Evaluation; Female; Humans; Liver Neoplasms; Male; Middle Aged; Mitoxantrone | 1986 |
Mitozantrone.
Topics: Breast Neoplasms; Humans; Leukemia; Liver Neoplasms; Lymphoma; Mitoxantrone; Neoplasms | 1986 |
Phase II studies of mitoxantrone in patients with primary liver cancer.
Topics: Adult; Aged; Anthraquinones; Antineoplastic Agents; Drug Evaluation; Humans; Leukopenia; Liver Neoplasms; Middle Aged; Mitoxantrone; Thrombocytopenia | 1985 |