mitoxantrone has been researched along with Cancer of Head in 16 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mitoxantrone is an anthracenedione, showing structural similarities to doxorubicin." | 5.27 | An EORTC phase II study of mitoxantrone in solid tumors and lymphomas. ( Armand, JP; Bastit, P; Cappelaere, P; De Jager, R; Earl, H; Fargeot, P; Keiling, R; Renard, J; Rubens, R; van Glabbeke, M, 1984) |
| "We have recently evaluated the combination of raltitrexed, levofolinic acid (LFA) and 5-fluorouracil (5-FU) in advanced head and neck and colorectal cancer, and we have shown that this combination is well tolerated and has clinical activity." | 5.09 | Phase I study of mitoxantrone, raltitrexed, levofolinic acid and 5-fluorouracil in advanced solid tumours. ( Avallone, A; Caponigro, F; Comella, G; Comella, P; De Rosa, V; Ionna, F; Rivellini, F, 2001) |
| "Leukopenia was mild, moderate, severe (1,000-1,999/mm3), and life-threatening (less than 1,000/mm3) in 17%, 23%, 42%, and 2% of courses, respectively." | 1.28 | Phase II trial of mitoxantrone in head and neck carcinoma. ( Ardalan, B; Benedetto, P; Desai, P; Feun, LG; Hussein, AM; Richman, SP; Savaraj, N; Sridhar, KS; Waldman, SM, 1991) |
| "Twenty patients with advanced squamous cell carcinomas (SCC) of the head and neck were entered into a phase II study of mitoxantrone at a dosage of either 12 mg/m2 or 14 mg/m2 given at 3 weekly intervals." | 1.28 | A phase II study of mitoxantrone in advanced squamous cell cancer of the head and neck. ( Levi, J; Page, J; Wheeler, H; Woods, RL, 1990) |
| " We have carried out a phase II trial of mitoxantrone using an every three weeks dosing schedule in patients with advanced head and neck cancers." | 1.27 | Phase II trial of mitoxantrone in head and neck cancer. ( Aapro, MS; Alberts, DS, 1984) |
| "Mitoxantrone is an anthracenedione, showing structural similarities to doxorubicin." | 1.27 | An EORTC phase II study of mitoxantrone in solid tumors and lymphomas. ( Armand, JP; Bastit, P; Cappelaere, P; De Jager, R; Earl, H; Fargeot, P; Keiling, R; Renard, J; Rubens, R; van Glabbeke, M, 1984) |
| " Fifty-three evaluable patients were treated with this agent at a dosage of 5 mg/M2/week." | 1.27 | Phase II study of mitoxantrone in advanced squamous cell carcinoma of the head and neck. A Southeastern Cancer Study Group trial. ( Birch, R; Gams, R; Velez-Garcia, E; Williams, SD, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (43.75) | 18.7374 |
| 1990's | 6 (37.50) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spugnini, EP | 1 |
| Fanciulli, M | 1 |
| Citro, G | 1 |
| Baldi, A | 1 |
| Aapro, MS | 1 |
| Alberts, DS | 2 |
| Mattox, DE | 2 |
| Clark, GM | 1 |
| Balcerzak, SP | 2 |
| O'Bryan, RM | 1 |
| Oishi, N | 1 |
| Stuckey, WJ | 1 |
| De Jager, R | 1 |
| Cappelaere, P | 1 |
| Armand, JP | 1 |
| Keiling, R | 1 |
| Fargeot, P | 1 |
| Bastit, P | 1 |
| van Glabbeke, M | 1 |
| Renard, J | 1 |
| Earl, H | 1 |
| Rubens, R | 1 |
| Peng, YM | 1 |
| Leigh, S | 1 |
| Davis, TP | 1 |
| Woodward, DL | 1 |
| Barista, I | 1 |
| Tekuzman, G | 1 |
| Firat, D | 1 |
| Baltali, E | 1 |
| Kansu, E | 1 |
| Kars, A | 1 |
| Ozisik, Y | 1 |
| Ruacan, S | 1 |
| Uzunalimoğlu, B | 1 |
| Karaağaoğlu, E | 1 |
| Verweij, J | 1 |
| de Mulder, PH | 1 |
| de Graeff, A | 1 |
| Vermorken, JB | 1 |
| Wildiers, J | 1 |
| Kerger, J | 1 |
| Schornagel, J | 1 |
| Cognetti, F | 1 |
| Kirkpatrick, A | 1 |
| Sahmoud, T | 1 |
| Lefebvre, JL | 1 |
| Caponigro, F | 1 |
| Avallone, A | 1 |
| Rivellini, F | 1 |
| Comella, P | 1 |
| Ionna, F | 1 |
| De Rosa, V | 1 |
| Comella, G | 1 |
| Thurnher, D | 1 |
| Kornfehl, J | 1 |
| Burian, M | 1 |
| Gedlicka, C | 1 |
| Selzer, E | 1 |
| Quint, C | 1 |
| Neuchrist, C | 1 |
| Kornek, GV | 1 |
| Sridhar, KS | 1 |
| Hussein, AM | 1 |
| Benedetto, P | 1 |
| Waldman, SM | 1 |
| Feun, LG | 1 |
| Savaraj, N | 1 |
| Richman, SP | 1 |
| Ardalan, B | 1 |
| Desai, P | 1 |
| Schnabel, T | 1 |
| Zamboglou, N | 1 |
| Schmitt, G | 1 |
| Von Hoff, DD | 1 |
| Wheeler, H | 1 |
| Woods, RL | 1 |
| Page, J | 1 |
| Levi, J | 1 |
| Stewart, DJ | 1 |
| Cripps, C | 1 |
| Maroun, JA | 1 |
| Fujita, J | 1 |
| Saijo, N | 1 |
| Williams, SD | 1 |
| Birch, R | 1 |
| Velez-Garcia, E | 1 |
| Gams, R | 1 |
2 reviews available for mitoxantrone and Cancer of Head
| Article | Year |
|---|---|
Preclinical models in electrochemotherapy: the role of veterinary patients.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma | 2012 |
[The role of chemotherapy in metastatic pulmonary tumors in a disease-oriented phase II study of anticancer agent].
Topics: Anthraquinones; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Drug Evaluation; Head and Neck | 1985 |
4 trials available for mitoxantrone and Cancer of Head
| Article | Year |
|---|---|
Phase II study on mitoxantrone in adenoid cystic carcinomas of the head and neck. EORTC Head and Neck Cancer Cooperative Group.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Adenoid Cystic; Confidence Intervals; Disease-Free Su | 1996 |
Phase I study of mitoxantrone, raltitrexed, levofolinic acid and 5-fluorouracil in advanced solid tumours.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluoroura | 2001 |
Ifosfamide and mitoxantrone in the treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Anemia; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, | 2001 |
Southwest Oncology Group study of mitoxantrone for treatment of patients with advanced adenoid cystic carcinoma of the head and neck.
Topics: Adult; Aged; Carcinoma, Adenoid Cystic; Head and Neck Neoplasms; Humans; Male; Middle Aged; Mitoxant | 1990 |
10 other studies available for mitoxantrone and Cancer of Head
| Article | Year |
|---|---|
Phase II trial of mitoxantrone in head and neck cancer.
Topics: Adult; Aged; Anthraquinones; Antineoplastic Agents; Drug Evaluation; Female; Head and Neck Neoplasms | 1984 |
Southwest Oncology Group study of Mitoxantrone for treatment of patients with advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Anthraquinones; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Femal | 1984 |
An EORTC phase II study of mitoxantrone in solid tumors and lymphomas.
Topics: Adolescent; Adult; Aged; Alopecia; Anthraquinones; Antineoplastic Agents; Breast Neoplasms; Carcinom | 1984 |
Disposition of mitoxantrone in patients.
Topics: Adenocarcinoma; Anthraquinones; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Fe | 1983 |
Non-Hodgkin's lymphomas in Turkey: eighteen years' experience at the Hacettepe University.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Anemia; Antineoplastic Agents; Ant | 1994 |
Phase II trial of mitoxantrone in head and neck carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Dose-Response R | 1991 |
[Intravenous mitoxantrone use and simultaneous radiotherapy as a palliative treatment in recurrent head and neck tumors].
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Combined Modality Therapy; Female; Head | 1991 |
A phase II study of mitoxantrone in advanced squamous cell cancer of the head and neck.
Topics: Aged; Carcinoma, Squamous Cell; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Mito | 1990 |
Phase II study of high-dose mitoxantrone in the treatment of recurrent squamous cell carcinoma of the head and neck.
Topics: Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Drug Evaluation; Drug Tolerance; Female; Head and | 1987 |
Phase II study of mitoxantrone in advanced squamous cell carcinoma of the head and neck. A Southeastern Cancer Study Group trial.
Topics: Anthraquinones; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Head and Neck Neop | 1985 |