Page last updated: 2024-10-31

mitoxantrone and Body Weight

mitoxantrone has been researched along with Body Weight in 12 studies

Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"Age is a known susceptibility factor for the cardiotoxicity of several anticancer drugs, including mitoxantrone (MTX)."7.81The age factor for mitoxantrone's cardiotoxicity: multiple doses render the adult mouse heart more susceptible to injury. ( Bastos, Mde L; Carvalho, F; Costa, VM; Dores-Sousa, JL; Duarte, JA; Seabra, V, 2015)
"In an attempt to improve the therapeutic effect of mitoxantrone (MTO) against breast cancer and its lymph node metastases, solid lipid nanoparticles (SLN) of MTO were prepared, characterized and evaluated on mice."7.73Solid lipid nanoparticles of mitoxantrone for local injection against breast cancer and its lymph node metastases. ( Chao, RB; Lu, B; Xiong, SB; Yang, H; Yin, XD, 2006)
"Age is a known susceptibility factor for the cardiotoxicity of several anticancer drugs, including mitoxantrone (MTX)."3.81The age factor for mitoxantrone's cardiotoxicity: multiple doses render the adult mouse heart more susceptible to injury. ( Bastos, Mde L; Carvalho, F; Costa, VM; Dores-Sousa, JL; Duarte, JA; Seabra, V, 2015)
"In an attempt to improve the therapeutic effect of mitoxantrone (MTO) against breast cancer and its lymph node metastases, solid lipid nanoparticles (SLN) of MTO were prepared, characterized and evaluated on mice."3.73Solid lipid nanoparticles of mitoxantrone for local injection against breast cancer and its lymph node metastases. ( Chao, RB; Lu, B; Xiong, SB; Yang, H; Yin, XD, 2006)
" Angiogenesis was induced in normal adult rat mesentery by intraperitoneal injection of a low dosage of VEGF-A."1.38Low-dosage metronomic chemotherapy and angiogenesis: topoisomerase inhibitors irinotecan and mitoxantrone stimulate VEGF-A-mediated angiogenesis. ( Albertsson, P; Lennernäs, B; Norrby, K, 2012)
"Mitoxantrone (MXN) has demonstrated therapeutic efficacy in the intraperitoneal treatment of malignancies."1.30Toxicity of a particulate formulation for the intraperitoneal application of mitoxantrone. ( Eichler, HG; Luftensteiner, CP; Paul, B; Schwendenwein, I; Viernstein, H; Wölfl, G, 1999)
"Ametantrone acetate is an antineoplastic drug chemically described as 1,4-bis [[2-[(2-hydroxyethyl)-amino] ethyl]amino] -9,10-anthracenedione diacetate salt."1.27Teratology studies of ametantrone acetate in rats and rabbits. ( Anderson, JA; de la Iglesia, FA; Fitzgerald, JE; Kim, SN; Petrere, JA; Schardein, JL, 1986)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19904 (33.33)18.7374
1990's2 (16.67)18.2507
2000's2 (16.67)29.6817
2010's3 (25.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Brandão, SR1
Reis-Mendes, A1
Domingues, P1
Duarte, JA2
Bastos, ML1
Carvalho, F2
Ferreira, R1
Costa, VM2
Dores-Sousa, JL1
Seabra, V1
Bastos, Mde L1
Niang, M1
Soukup, T1
Zivný, P1
Tomšík, P1
Bukač, J1
Rezáčová, M1
Stoklasová, A1
Cerman, J1
Sišpera, L1
Albertsson, P1
Lennernäs, B1
Norrby, K1
Almond, BA1
Hadba, AR1
Freeman, ST1
Cuevas, BJ1
York, AM1
Detrisac, CJ1
Goldberg, EP1
Lu, B1
Xiong, SB1
Yang, H1
Yin, XD1
Chao, RB1
Mullen, BM1
Mattox, DE1
Von Hoff, DD1
Hearne, EM1
Luftensteiner, CP1
Schwendenwein, I1
Eichler, HG1
Paul, B1
Wölfl, G1
Viernstein, H1
Los, G1
Nagel, JD1
McVie, JG1
Mulder, PO1
Bouman, JG1
Gietema, JA1
Van Rijsbergen, H1
Mulder, NH1
Van der Geest, S1
De Vries, EG1
Chandrasekaran, B1
Dimling, J1
Capizzi, RL1
Petrere, JA1
Kim, SN1
Anderson, JA1
Fitzgerald, JE1
de la Iglesia, FA1
Schardein, JL1

Trials

1 trial available for mitoxantrone and Body Weight

ArticleYear
Hyperalimentation in autologous bone marrow transplantation for solid tumors. Comparison of total parenteral versus partial parenteral plus enteral nutrition.
    Cancer, 1989, Nov-15, Volume: 64, Issue:10

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Bone Marrow Transplantation; Com

1989

Other Studies

11 other studies available for mitoxantrone and Body Weight

ArticleYear
Exploring the aging effect of the anticancer drugs doxorubicin and mitoxantrone on cardiac mitochondrial proteome using a murine model.
    Toxicology, 2021, Volume: 459

    Topics: Aging; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Body Weight; Citrate (si)-Syntha

2021
The age factor for mitoxantrone's cardiotoxicity: multiple doses render the adult mouse heart more susceptible to injury.
    Toxicology, 2015, Mar-02, Volume: 329

    Topics: Age Factors; Animals; Antineoplastic Agents; Aspartate Aminotransferases; Biomarkers; Body Weight; C

2015
Biochemical and pharmacological effects of mitoxantrone and acetyl-L-carnitine in mice with a solid form of Ehrlich tumour.
    Chemotherapy, 2011, Volume: 57, Issue:1

    Topics: Acetylcarnitine; Animals; Antineoplastic Agents; Bilirubin; Body Weight; Carcinoma, Ehrlich Tumor; F

2011
Low-dosage metronomic chemotherapy and angiogenesis: topoisomerase inhibitors irinotecan and mitoxantrone stimulate VEGF-A-mediated angiogenesis.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2012, Volume: 120, Issue:2

    Topics: Animals; Body Weight; Camptothecin; Endothelial Cells; Irinotecan; Male; Mesentery; Mitoxantrone; Ne

2012
Efficacy of mitoxantrone-loaded albumin microspheres for intratumoral chemotherapy of breast cancer.
    Journal of controlled release : official journal of the Controlled Release Society, 2003, Aug-28, Volume: 91, Issue:1-2

    Topics: Adenocarcinoma; Albumins; Animals; Antineoplastic Agents; Body Weight; Female; Mammary Neoplasms, Ex

2003
Solid lipid nanoparticles of mitoxantrone for local injection against breast cancer and its lymph node metastases.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2006, Volume: 28, Issue:1-2

    Topics: Algorithms; Animals; Antineoplastic Agents; Body Weight; Breast Neoplasms; Cell Line, Tumor; Chlorof

2006
The effect of preoperative adriamycin and dihydroxyanthracenedione on wound healing.
    The Laryngoscope, 1981, Volume: 91, Issue:9 Pt 1

    Topics: Animals; Anthraquinones; Antineoplastic Agents; Body Weight; Doxorubicin; Female; Mitoxantrone; Preo

1981
Toxicity of a particulate formulation for the intraperitoneal application of mitoxantrone.
    International journal of pharmaceutics, 1999, Apr-15, Volume: 180, Issue:2

    Topics: Animals; Antineoplastic Agents; Blood Cell Count; Body Weight; Eating; Female; Humans; Injections, I

1999
Anti-tumor effect of cisplatin, carboplatin, mitoxantrone, and doxorubicin on peritoneal tumor growth after intraperitoneal and intravenous chemotherapy: a comparative study.
    Selective cancer therapeutics, 1990,Summer, Volume: 6, Issue:2

    Topics: Animals; Antineoplastic Agents; Body Weight; Carboplatin; Cisplatin; Doxorubicin; Injections, Intrap

1990
Cross-resistance of menogaril and mitoxantrone in a subline of P388 leukemia resistant to doxorubicin.
    Cancer treatment reports, 1987, Volume: 71, Issue:2

    Topics: Animals; Antineoplastic Agents; Body Weight; Cell Line; Daunorubicin; Doxorubicin; Drug Resistance;

1987
Teratology studies of ametantrone acetate in rats and rabbits.
    Teratology, 1986, Volume: 34, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Dose-Response Relationship, Drug; Female; Gestati

1986