mitoxantrone has been researched along with Bilirubinemia in 4 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the safety and efficacy of mitoxantrone use in hyperbilirubinemic breast cancer patients, a prospectively determined dosage schedule was evaluated in a multi-center trial." | 9.06 | Mitoxantrone use in breast cancer patients with elevated bilirubin. ( Bulcavage, L; Chlebowski, RT; Elashoff, R; Henderson, IC; Rivest, R; Woodcock, T, 1989) |
| "To determine the safety and efficacy of mitoxantrone use in hyperbilirubinemic breast cancer patients, a prospectively determined dosage schedule was evaluated in a multi-center trial." | 5.06 | Mitoxantrone use in breast cancer patients with elevated bilirubin. ( Bulcavage, L; Chlebowski, RT; Elashoff, R; Henderson, IC; Rivest, R; Woodcock, T, 1989) |
| " In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome." | 4.80 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tukey, RH | 1 |
| Strassburg, CP | 1 |
| Feldman, EJ | 1 |
| Seiter, K | 1 |
| Traganos, F | 1 |
| Darzynkiewicz, Z | 1 |
| Goff, H | 1 |
| Pozzuoli, M | 1 |
| Baskind, P | 1 |
| Santos, S | 1 |
| Ahmed, T | 1 |
| Bennett, JM | 1 |
| Young, MS | 1 |
| Liesveld, JL | 1 |
| Paietta, E | 1 |
| Miller, KB | 1 |
| Lazarus, HM | 1 |
| Marsh, RD | 1 |
| Friedenberg, WR | 1 |
| Saba, HT | 1 |
| Hayes, FA | 1 |
| Dewald, GW | 1 |
| Hiddemann, W | 1 |
| Rowe, JM | 1 |
| Chlebowski, RT | 1 |
| Bulcavage, L | 1 |
| Henderson, IC | 1 |
| Woodcock, T | 1 |
| Rivest, R | 1 |
| Elashoff, R | 1 |
1 review available for mitoxantrone and Bilirubinemia
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; | 2000 |
3 trials available for mitoxantrone and Bilirubinemia
| Article | Year |
|---|---|
Phase II evaluation of a high-dose mitoxantrone based induction regimen in untreated adults with acute myeloid leukemia.
Topics: Actuarial Analysis; Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marro | 2000 |
Phase II study of combination human recombinant GM-CSF with intermediate-dose cytarabine and mitoxantrone chemotherapy in patients with high-risk myelodysplastic syndromes (RAEB, RAEBT, and CMML): an Eastern Cooperative Oncology Group Study.
Topics: Aged; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Bon | 2001 |
Mitoxantrone use in breast cancer patients with elevated bilirubin.
Topics: Adenocarcinoma; Breast Neoplasms; Female; Humans; Hyperbilirubinemia; Liver Diseases; Middle Aged; M | 1989 |