Page last updated: 2024-10-31

mitoxantrone and Bacteremia

mitoxantrone has been researched along with Bacteremia in 5 studies

Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.

Bacteremia: The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.

Research Excerpts

ExcerptRelevanceReference
" Because both P-glycoprotein- and platinum-induced resistance appear to be clinically important and can be reversed in vitro with a short exposure of cyclosporin A (CSA) at 2000 and 5000 ng/ml, respectively, we undertook a trial of high-dose chemotherapy with carboplatin (1500mg/m2), mitoxantrone (75 mg/m2), and cyclophosphamide (120 mg/kg) over a 5-day period combined with escalating doses of CSA."2.68High-dose chemotherapy combined with escalating doses of cyclosporin A and an autologous bone marrow transplant for the treatment of drug-resistant solid tumors: a phase I clinical trial. ( Bayer, R; Camarda, M; Kinch, L; Loutfi, S; Peace, D; Rad, N; Sosman, J; Stiff, PJ; Tan, S, 1995)
"Neutropenia was present in 74."1.32Infectious complications in pediatric acute myeloid leukemia: analysis of the prospective multi-institutional clinical trial AML-BFM 93. ( Creutzig, U; Kaiser, J; Klingebiel, T; Lehrnbecher, T; Reinhardt, D; Varwig, D, 2004)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Roy Moulik, N1
Keerthivasagam, S1
Velagala, SV1
Gollamudi, VRM1
Agiwale, J1
Dhamne, C1
Chichra, A1
Srinivasan, S1
Shetty, D1
Jain, H1
Subramanian, PG1
Tembhare, P1
Chatterjee, G1
Patkar, N1
Narula, G1
Banavali, S1
Lehrnbecher, T1
Varwig, D1
Kaiser, J1
Reinhardt, D1
Klingebiel, T1
Creutzig, U1
Khalil, A1
Ciobanu, N1
Sparano, JA1
Gucalp, R1
Dutcher, JP1
Wiernik, PH1
Brodsky, AL1
Melero, MJ1
Minissale, CJ1
Sánchez Avalos, JC1
Stiff, PJ1
Bayer, R1
Tan, S1
Camarda, M1
Sosman, J1
Peace, D1
Kinch, L1
Rad, N1
Loutfi, S1

Trials

3 trials available for mitoxantrone and Bacteremia

ArticleYear
Pilot study of high-dose mitoxantrone and busulfan plus autologous bone transplantation in patients with advanced malignancies.
    Bone marrow transplantation, 1995, Volume: 15, Issue:1

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Bone Marrow Trans

1995
[Chemotherapy schedules and bacteremia in adult patients with acute leukemia].
    Medicina, 1996, Volume: 56, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Anti

1996
High-dose chemotherapy combined with escalating doses of cyclosporin A and an autologous bone marrow transplant for the treatment of drug-resistant solid tumors: a phase I clinical trial.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Bone Marrow Transplantation; Carb

1995

Other Studies

2 other studies available for mitoxantrone and Bacteremia

ArticleYear
Treating relapsed B cell-precursor ALL in children with a setting-adapted mitoxantrone-based intensive chemotherapy protocol (TMH rALL-18 PROTOCOL) - experience from Tata Memorial Hospital, India.
    Annals of hematology, 2023, Volume: 102, Issue:10

    Topics: Bacteremia; Child; Hospitals; Humans; India; Mitoxantrone; Prospective Studies; Retrospective Studie

2023
Infectious complications in pediatric acute myeloid leukemia: analysis of the prospective multi-institutional clinical trial AML-BFM 93.
    Leukemia, 2004, Volume: 18, Issue:1

    Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Bacteria; Chi

2004