mitoxantrone has been researched along with Arthritis, Rheumatoid in 6 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When rats with developing or established adjuvant arthritis are treated with mitoxantrone, the hind paw inflammation associated with the disease is inhibited." | 7.67 | Studies of the effect of mitoxantrone on adjuvant induced arthritis in rats. ( Kerwar, SS; Oronsky, AL; Sloboda, AE, 1986) |
| "When rats with developing or established adjuvant arthritis are treated with mitoxantrone, the hind paw inflammation associated with the disease is inhibited." | 3.67 | Studies of the effect of mitoxantrone on adjuvant induced arthritis in rats. ( Kerwar, SS; Oronsky, AL; Sloboda, AE, 1986) |
| "Azathioprine sodium use was observed more frequently in cases (odds ratio [OR], 7." | 1.46 | Association of Therapy for Autoimmune Disease With Myelodysplastic Syndromes and Acute Myeloid Leukemia. ( Al-Kali, A; Castro, J; Dueck, A; Ertz-Archambault, N; Finn, L; Foran, J; Gauthier, S; Kelemen, K; Kosiorek, H; Marino, R; Mesa, RA; Palmer, J; Sproat, LZ; Taylor, GE; Tibes, R, 2017) |
| "Mitoxantrone was administered as high dose (1 mg/kg body weight five times after immunization or after booster with collagen II) or low dose (3 microg/mouse, 5 days/week starting after collagen II immunization or after booster)." | 1.33 | Topoisomerase II inhibitors, irrespective of their chemical composition, ameliorate experimental arthritis. ( Isaksson, O; Tarkowski, A; Verdrengh, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Sarhan, SA | 1 |
| Kamal, DE | 1 |
| Hamed, MS | 1 |
| Mostafa, DI | 1 |
| Boddu, PC | 1 |
| Zeidan, AM | 1 |
| Atisha-Fregoso, Y | 1 |
| Lima, G | 1 |
| Pascual-Ramos, V | 1 |
| Baños-Peláez, M | 1 |
| Fragoso-Loyo, H | 1 |
| Jakez-Ocampo, J | 1 |
| Contreras-Yáñez, I | 1 |
| Llorente, L | 1 |
| Ertz-Archambault, N | 1 |
| Kosiorek, H | 1 |
| Taylor, GE | 1 |
| Kelemen, K | 1 |
| Dueck, A | 1 |
| Castro, J | 1 |
| Marino, R | 1 |
| Gauthier, S | 1 |
| Finn, L | 1 |
| Sproat, LZ | 1 |
| Palmer, J | 1 |
| Mesa, RA | 1 |
| Al-Kali, A | 1 |
| Foran, J | 1 |
| Tibes, R | 1 |
| Verdrengh, M | 1 |
| Isaksson, O | 1 |
| Tarkowski, A | 1 |
| Sloboda, AE | 1 |
| Oronsky, AL | 1 |
| Kerwar, SS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| INCMNSZ Early Rheumatoid Arthritis Cohort[NCT03389711] | 237 participants (Anticipated) | Observational | 2004-02-04 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for mitoxantrone and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Myeloid disorders after autoimmune disease.
Topics: Arthritis, Rheumatoid; Cyclophosphamide; Genetic Predisposition to Disease; Humans; Immunosuppressiv | 2019 |
5 other studies available for mitoxantrone and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Validity and reliability of the Arabic version of the Self-Efficacy for Managing Chronic Disease scale in rheumatoid arthritis patients.
Topics: Arthritis, Rheumatoid; Chronic Disease; Humans; Mitoxantrone; Psychometrics; Quality of Life; Reprod | 2022 |
Rheumatoid Arthritis Disease Activity Is Determinant for ABCB1 and ABCG2 Drug-Efflux Transporters Function.
Topics: Adult; Arthritis, Rheumatoid; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Tr | 2016 |
Association of Therapy for Autoimmune Disease With Myelodysplastic Syndromes and Acute Myeloid Leukemia.
Topics: Aged; Aged, 80 and over; Arthritis, Rheumatoid; Autoimmune Diseases; Azathioprine; Case-Control Stud | 2017 |
Topoisomerase II inhibitors, irrespective of their chemical composition, ameliorate experimental arthritis.
Topics: Animals; Antibody Formation; Arthritis, Experimental; Arthritis, Rheumatoid; Collagen Type II; Dose- | 2005 |
Studies of the effect of mitoxantrone on adjuvant induced arthritis in rats.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Arthritis, Rh | 1986 |