Page last updated: 2024-10-31

mitoxantrone and Anemia

mitoxantrone has been researched along with Anemia in 11 studies

Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.

Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.

Research Excerpts

ExcerptRelevanceReference
"Grade 3/4 neutropenia was observed in 29 patients (58%) with four neutropenic episodes."6.69First-line treatment of metastatic breast cancer with mitoxantrone, vinorelbine, and carboplatin. ( Agelaki, S; Androulakis, N; Georgoulias, V; Hatzidaki, D; Kakolyris, S; Koukourakis, M; Kourousis, C; Samonis, G; Tsiftsis, D; Vamvakas, L, 1999)
"For previously treated advanced breast cancer, there is no standard second-line therapy."5.30Treatment of previously treated metastatic breast cancer by mitoxantrone and 48-hour continuous infusion of high-dose 5-FU and leucovorin (MFL): low palliative benefit and high treatment-related toxicity. ( Chen, PM; Chiou, TJ; Hsieh, RK; Liu, JH; Tung, SL; Wang, WS; Yen, CC, 1997)
"A comparison of patients receiving combination chemotherapy with mitomycin C, mitozantrone and methotrexate (3M) with and without tamoxifen for treatment of primary breast cancer indicates an increased risk of anaemia (P < 0."5.07A toxic interaction between mitomycin C and tamoxifen causing the haemolytic uraemic syndrome. ( Ashley, SE; Luckit, J; Montes, A; O'Brien, ME; Powles, TJ; Treleaven, J, 1993)
"Mitoxantrone is used for aggressive multiple sclerosis (MS), but concerns about safety, including cardiotoxicity and other laboratory measures, prevail."3.76Cardiotoxicity and other adverse events associated with mitoxantrone treatment for MS. ( Geddes, J; Isserow, S; Kingwell, E; Koch, M; Leung, B; Rieckmann, P; Tremlett, H, 2010)
"Grade 3/4 neutropenia was observed in 29 patients (58%) with four neutropenic episodes."2.69First-line treatment of metastatic breast cancer with mitoxantrone, vinorelbine, and carboplatin. ( Agelaki, S; Androulakis, N; Georgoulias, V; Hatzidaki, D; Kakolyris, S; Koukourakis, M; Kourousis, C; Samonis, G; Tsiftsis, D; Vamvakas, L, 1999)
"For previously treated advanced breast cancer, there is no standard second-line therapy."1.30Treatment of previously treated metastatic breast cancer by mitoxantrone and 48-hour continuous infusion of high-dose 5-FU and leucovorin (MFL): low palliative benefit and high treatment-related toxicity. ( Chen, PM; Chiou, TJ; Hsieh, RK; Liu, JH; Tung, SL; Wang, WS; Yen, CC, 1997)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (45.45)18.2507
2000's4 (36.36)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaneko, H1
Katoh, T1
Hirano, I1
Hasegawa, A1
Tsujita, T1
Yamamoto, M1
Shimizu, R1
Kingwell, E1
Koch, M1
Leung, B1
Isserow, S1
Geddes, J1
Rieckmann, P1
Tremlett, H1
Sheen, WC1
Chen, JS1
Wang, HM1
Yang, TS1
Liaw, CC1
Lin, YC1
Errante, D1
Bianco, A1
Aversa, SML1
Salvagno, L1
Barista, I1
Tekuzman, G1
Firat, D1
Baltali, E1
Kansu, E1
Kars, A1
Ozisik, Y1
Ruacan, S1
Uzunalimoğlu, B1
Karaağaoğlu, E1
Damon, LE1
Rugo, HS1
Ries, CA1
Linker, CA1
Montes, A1
Powles, TJ1
O'Brien, ME1
Ashley, SE1
Luckit, J1
Treleaven, J1
Yen, CC1
Tung, SL1
Hsieh, RK1
Chiou, TJ1
Liu, JH1
Wang, WS1
Chen, PM1
Kakolyris, S1
Kourousis, C1
Koukourakis, M1
Androulakis, N1
Vamvakas, L1
Agelaki, S1
Hatzidaki, D1
Samonis, G1
Tsiftsis, D1
Georgoulias, V1
Thurnher, D1
Kornfehl, J1
Burian, M1
Gedlicka, C1
Selzer, E1
Quint, C1
Neuchrist, C1
Kornek, GV1
Siemens, HJ1
Gerke, P1
Steinhoff, J1
Roth-Isigkeit, A1
Wagner, K1
Brückner, S1

Trials

3 trials available for mitoxantrone and Anemia

ArticleYear
A toxic interaction between mitomycin C and tamoxifen causing the haemolytic uraemic syndrome.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:13

    Topics: Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Interact

1993
First-line treatment of metastatic breast cancer with mitoxantrone, vinorelbine, and carboplatin.
    American journal of clinical oncology, 1999, Volume: 22, Issue:6

    Topics: Adult; Aged; Alopecia; Anemia; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplas

1999
Ifosfamide and mitoxantrone in the treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck.
    Anti-cancer drugs, 2001, Volume: 12, Issue:3

    Topics: Adult; Aged; Anemia; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Carcinoma,

2001

Other Studies

8 other studies available for mitoxantrone and Anemia

ArticleYear
Induction of erythropoietin gene expression in epithelial cells by chemicals identified in GATA inhibitor screenings.
    Genes to cells : devoted to molecular & cellular mechanisms, 2017, Volume: 22, Issue:11

    Topics: Anemia; Animals; Base Sequence; Cells, Cultured; CRISPR-Cas Systems; Epithelial Cells; Erythropoieti

2017
Cardiotoxicity and other adverse events associated with mitoxantrone treatment for MS.
    Neurology, 2010, Jun-01, Volume: 74, Issue:22

    Topics: Adult; Age Factors; Analgesics; Anemia; Female; Follow-Up Studies; Humans; Liver Diseases; Male; Mid

2010
A modified low-dose regimen of mitoxantrone and prednisolone in patients with androgen-independent prostate cancer.
    Japanese journal of clinical oncology, 2004, Volume: 34, Issue:6

    Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Drug Administrati

2004
Comment on: 'Non-Hodgkin's lymphoma in very elderly patients over 80 years. A descriptive analysis of clinical presentation and outcome'.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:7

    Topics: Administration, Oral; Aged, 80 and over; Anemia; Antineoplastic Combined Chemotherapy Protocols; Ble

2008
Non-Hodgkin's lymphomas in Turkey: eighteen years' experience at the Hacettepe University.
    Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Anemia; Antineoplastic Agents; Ant

1994
Post-remission cytopenias following intense induction chemotherapy for acute myeloid leukemia.
    Leukemia, 1994, Volume: 8, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Anemia; Antineoplastic Combined Chemotherapy Protocols; Bone Marro

1994
Treatment of previously treated metastatic breast cancer by mitoxantrone and 48-hour continuous infusion of high-dose 5-FU and leucovorin (MFL): low palliative benefit and high treatment-related toxicity.
    Japanese journal of clinical oncology, 1997, Volume: 27, Issue:5

    Topics: Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasm

1997
A prolonged APTT in a patient with a low grade malignant NHL - a case report.
    Haematologica, 2002, Volume: 87, Issue:2

    Topics: Anemia; Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Blood Coagulation Factors; C

2002