mitoxantrone has been researched along with Adenocystic Carcinoma in 5 studies
Mitoxantrone: An anthracenedione-derived antineoplastic agent.
mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leukopenia was mild, moderate, severe (1,000-1,999/mm3), and life-threatening (less than 1,000/mm3) in 17%, 23%, 42%, and 2% of courses, respectively." | 1.28 | Phase II trial of mitoxantrone in head and neck carcinoma. ( Ardalan, B; Benedetto, P; Desai, P; Feun, LG; Hussein, AM; Richman, SP; Savaraj, N; Sridhar, KS; Waldman, SM, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, JW | 1 |
| Qiu, WL | 1 |
| He, RG | 1 |
| Verweij, J | 1 |
| de Mulder, PH | 1 |
| de Graeff, A | 1 |
| Vermorken, JB | 1 |
| Wildiers, J | 1 |
| Kerger, J | 1 |
| Schornagel, J | 1 |
| Cognetti, F | 1 |
| Kirkpatrick, A | 1 |
| Sahmoud, T | 1 |
| Lefebvre, JL | 1 |
| Sridhar, KS | 1 |
| Hussein, AM | 1 |
| Benedetto, P | 1 |
| Waldman, SM | 1 |
| Feun, LG | 1 |
| Savaraj, N | 1 |
| Richman, SP | 1 |
| Ardalan, B | 1 |
| Desai, P | 1 |
| Mattox, DE | 1 |
| Von Hoff, DD | 2 |
| Balcerzak, SP | 1 |
| Shenkenberg, TD | 1 |
2 trials available for mitoxantrone and Adenocystic Carcinoma
| Article | Year |
|---|---|
Phase II study on mitoxantrone in adenoid cystic carcinomas of the head and neck. EORTC Head and Neck Cancer Cooperative Group.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Adenoid Cystic; Confidence Intervals; Disease-Free Su | 1996 |
Southwest Oncology Group study of mitoxantrone for treatment of patients with advanced adenoid cystic carcinoma of the head and neck.
Topics: Adult; Aged; Carcinoma, Adenoid Cystic; Head and Neck Neoplasms; Humans; Male; Middle Aged; Mitoxant | 1990 |
3 other studies available for mitoxantrone and Adenocystic Carcinoma
| Article | Year |
|---|---|
[Verapamil enhancement of antitumor effect of mitoxantrone on ACC-2 cell line in vitro and in vivo].
Topics: Animals; Carcinoma, Adenoid Cystic; DNA, Neoplasm; Drug Synergism; Female; Humans; Male; Mice; Mice, | 1994 |
Phase II trial of mitoxantrone in head and neck carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Dose-Response R | 1991 |
Possible mitoxantrone-induced amenorrhea.
Topics: Adult; Amenorrhea; Anthraquinones; Carcinoma, Adenoid Cystic; Estradiol; Female; Follicle Stimulatin | 1986 |