Page last updated: 2024-10-31

mitotane and Vomiting

mitotane has been researched along with Vomiting in 3 studies

Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.

Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.

Research Excerpts

ExcerptRelevanceReference
" Measurement of o,p'-DDD and its metabolites in plasma may prove clinically useful in developing effective but less toxic dosage schedules."1.26o,p'-DDD (mitotane) therapy of adrenal cortical carcinoma: observations on drug dosage, toxicity, and steroid replacement. ( Borden, EC; Citrin, DL; Davis, TE; Hogan, TF; Johnson, BM; Nakamura, S, 1978)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
den Hertog, E1
Braakman, JC1
Teske, E1
Kooistra, HS1
Rijnberk, A1
Ling, GV1
Lowenstine, LJ1
Pulley, LT1
Kaneko, JJ1
Hogan, TF1
Citrin, DL1
Johnson, BM1
Nakamura, S1
Davis, TE1
Borden, EC1

Trials

1 trial available for mitotane and Vomiting

ArticleYear
Results of non-selective adrenocorticolysis by o,p'-DDD in 129 dogs with pituitary-dependent hyperadrenocorticism.
    The Veterinary record, 1999, Jan-02, Volume: 144, Issue:1

    Topics: Adrenal Glands; Animals; Anorexia; Antineoplastic Agents, Hormonal; Body Weight; Cushing Syndrome; D

1999

Other Studies

2 other studies available for mitotane and Vomiting

ArticleYear
Diabetes mellitus in dogs: a review of initial evaluation, immediate and long-term management, and outcome.
    Journal of the American Veterinary Medical Association, 1977, Mar-01, Volume: 170, Issue:5

    Topics: Amylases; Animals; Anorexia; Bicarbonates; Blood Glucose; Blood Urea Nitrogen; Cushing Syndrome; Deh

1977
o,p'-DDD (mitotane) therapy of adrenal cortical carcinoma: observations on drug dosage, toxicity, and steroid replacement.
    Cancer, 1978, Volume: 42, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adult; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Male; M

1978