mitotane and Thyroid Neoplasms studies

mitotane and Thyroid Neoplasms

mitotane has been researched along with Thyroid Neoplasms in 4 studies

Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.

Thyroid Neoplasms: Tumors or cancer of the THYROID GLAND.

Research Excerpts

Excerpt	Relevance	Reference
"Treatment with mitotane (50 µM for 24 h) decreased the viability of FTC‑133, BCPAP, SW1736, C643 and TT cells by 12, 59, 54, 31 and 66%, respectively."	1.51	Mitotane induces mitochondrial membrane depolarization and apoptosis in thyroid cancer cells. ( Bikas, A; Burman, K; Costello, J; Hoperia, V; Jensen, K; Kaltsas, G; Patel, A; Vasko, V; Wartofsky, L, 2019)

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (25.00)	18.2507
2000's	2 (50.00)	29.6817
2010's	1 (25.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

1 (25.00)

18.2507

2000's

2 (50.00)

29.6817

2010's

1 (25.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Bikas, A	1
Jensen, K	1
Patel, A	1
Costello, J	1
Kaltsas, G	1
Hoperia, V	1
Wartofsky, L	1
Burman, K	1
Vasko, V	1
Valo, I	1
Verrièle, V	1
Giraud, P	1
Lorimier, G	1
Guyétant, S	1
Sommelet, D	1
Solomon, CG	1
Dluhy, RG	1
Schott, M	1
Scherbaum, WA	1
Feldkamp, J	1

Studies

Bikas, A

Jensen, K

Patel, A

Costello, J

Kaltsas, G

Hoperia, V

Wartofsky, L

Burman, K

Vasko, V

Valo, I

Verrièle, V

Giraud, P

Lorimier, G

Guyétant, S

Sommelet, D

Solomon, CG

Dluhy, RG

Schott, M

Scherbaum, WA

Feldkamp, J

Reviews

1 review available for mitotane and Thyroid Neoplasms

Article	Year
[Drug therapy of endocrine neoplasms. Part I: Thyroid neoplasms, adrenal neoplasms and parathyroid neoplasms]. Medizinische Klinik (Munich, Germany : 1983), 2000, Jan-15, Volume: 95, Issue:1 Topics: Adrenal Gland Neoplasms; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Proto	2000

Article

Year

[Drug therapy of endocrine neoplasms. Part I: Thyroid neoplasms, adrenal neoplasms and parathyroid neoplasms].

Medizinische Klinik (Munich, Germany : 1983), 2000, Jan-15, Volume: 95, Issue:1

Topics: Adrenal Gland Neoplasms; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Proto

2000

Other Studies

3 other studies available for mitotane and Thyroid Neoplasms

Article	Year
Mitotane induces mitochondrial membrane depolarization and apoptosis in thyroid cancer cells. International journal of oncology, 2019, Volume: 55, Issue:1 Topics: Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Damage; Ge	2019
[Thyroid metastases of an adrenocortical carcinoma 41 years after the diagnosis of the primary tumor]. Annales de pathologie, 2004, Volume: 24, Issue:3 Topics: Adenocarcinoma, Clear Cell; Adrenal Cortex Neoplasms; Adrenalectomy; Antineoplastic Agents; Biomarke	2004
Paraneoplastic endocrine syndromes. Current therapy in endocrinology and metabolism, 1994, Volume: 5 Topics: Acromegaly; Adrenocorticotropic Hormone; Aminoglutethimide; Bromocriptine; Calcitonin; Cushing Syndr	1994

Article

Year

Mitotane induces mitochondrial membrane depolarization and apoptosis in thyroid cancer cells.

International journal of oncology, 2019, Volume: 55, Issue:1

Topics: Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Damage; Ge

2019

[Thyroid metastases of an adrenocortical carcinoma 41 years after the diagnosis of the primary tumor].

Annales de pathologie, 2004, Volume: 24, Issue:3

Topics: Adenocarcinoma, Clear Cell; Adrenal Cortex Neoplasms; Adrenalectomy; Antineoplastic Agents; Biomarke

2004

Paraneoplastic endocrine syndromes.

Current therapy in endocrinology and metabolism, 1994, Volume: 5

Topics: Acromegaly; Adrenocorticotropic Hormone; Aminoglutethimide; Bromocriptine; Calcitonin; Cushing Syndr

1994