Page last updated: 2024-10-31

mitotane and Syndrome

mitotane has been researched along with Syndrome in 4 studies

Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.

Syndrome: A characteristic symptom complex.

Research Excerpts

ExcerptRelevanceReference
"The purpose of the study was to evaluate intermediate adrenal steroid hormones (ISH) in neutered dogs with hair cycle arrest (Alopecia X) during treatment with melatonin, and to see if hair re-growth is associated with sex hormone concentrations within the normal ranges."9.11Adrenal steroid hormone concentrations in dogs with hair cycle arrest (Alopecia X) before and during treatment with melatonin and mitotane. ( Frank, LA; Hnilica, KA; Oliver, JW, 2004)
"The purpose of the study was to evaluate intermediate adrenal steroid hormones (ISH) in neutered dogs with hair cycle arrest (Alopecia X) during treatment with melatonin, and to see if hair re-growth is associated with sex hormone concentrations within the normal ranges."5.11Adrenal steroid hormone concentrations in dogs with hair cycle arrest (Alopecia X) before and during treatment with melatonin and mitotane. ( Frank, LA; Hnilica, KA; Oliver, JW, 2004)
" This dosage was maintained for an additional 16 weeks (cumulative dose 602 g, plasma MT maximum level 12 microg/ml), and then stopped because of sustained signs of hypoadrenalism requiring prednisone replacement."1.33A six month mitotane course induced sustained correction of hypercortisolism in a young woman with PPNAD and Carney complex. ( Campo, M; Cignarelli, M; Giorgino, F; Logoluso, F; Margaglione, M; Marino, A; Picca, G, 2005)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Patalano, A1
Brancato, V1
Mantero, F1
Frank, LA1
Hnilica, KA1
Oliver, JW1
Cignarelli, M1
Picca, G1
Campo, M1
Margaglione, M1
Marino, A1
Logoluso, F1
Giorgino, F1
Austin, VH1

Reviews

1 review available for mitotane and Syndrome

ArticleYear
Adrenocortical cancer treatment.
    Hormone research, 2009, Volume: 71 Suppl 1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Algorithms; Antineoplastic Combined Chemotherapy

2009

Trials

1 trial available for mitotane and Syndrome

ArticleYear
Adrenal steroid hormone concentrations in dogs with hair cycle arrest (Alopecia X) before and during treatment with melatonin and mitotane.
    Veterinary dermatology, 2004, Volume: 15, Issue:5

    Topics: Administration, Oral; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Alopecia; Androstenedion

2004

Other Studies

2 other studies available for mitotane and Syndrome

ArticleYear
A six month mitotane course induced sustained correction of hypercortisolism in a young woman with PPNAD and Carney complex.
    Journal of endocrinological investigation, 2005, Volume: 28, Issue:1

    Topics: Adrenal Cortex Diseases; Adrenal Glands; Adult; Antineoplastic Agents, Hormonal; DNA; Female; Humans

2005
Selected case reports in small animal dermatology.
    Modern veterinary practice, 1975, Volume: 56, Issue:1

    Topics: Alopecia Areata; Animals; Calcinosis; Cat Diseases; Cats; Dermatitis; Dog Diseases; Dogs; Epinephrin

1975