mitotane has been researched along with Syndrome in 4 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
Syndrome: A characteristic symptom complex.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of the study was to evaluate intermediate adrenal steroid hormones (ISH) in neutered dogs with hair cycle arrest (Alopecia X) during treatment with melatonin, and to see if hair re-growth is associated with sex hormone concentrations within the normal ranges." | 9.11 | Adrenal steroid hormone concentrations in dogs with hair cycle arrest (Alopecia X) before and during treatment with melatonin and mitotane. ( Frank, LA; Hnilica, KA; Oliver, JW, 2004) |
| "The purpose of the study was to evaluate intermediate adrenal steroid hormones (ISH) in neutered dogs with hair cycle arrest (Alopecia X) during treatment with melatonin, and to see if hair re-growth is associated with sex hormone concentrations within the normal ranges." | 5.11 | Adrenal steroid hormone concentrations in dogs with hair cycle arrest (Alopecia X) before and during treatment with melatonin and mitotane. ( Frank, LA; Hnilica, KA; Oliver, JW, 2004) |
| " This dosage was maintained for an additional 16 weeks (cumulative dose 602 g, plasma MT maximum level 12 microg/ml), and then stopped because of sustained signs of hypoadrenalism requiring prednisone replacement." | 1.33 | A six month mitotane course induced sustained correction of hypercortisolism in a young woman with PPNAD and Carney complex. ( Campo, M; Cignarelli, M; Giorgino, F; Logoluso, F; Margaglione, M; Marino, A; Picca, G, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Patalano, A | 1 |
| Brancato, V | 1 |
| Mantero, F | 1 |
| Frank, LA | 1 |
| Hnilica, KA | 1 |
| Oliver, JW | 1 |
| Cignarelli, M | 1 |
| Picca, G | 1 |
| Campo, M | 1 |
| Margaglione, M | 1 |
| Marino, A | 1 |
| Logoluso, F | 1 |
| Giorgino, F | 1 |
| Austin, VH | 1 |
1 review available for mitotane and Syndrome
| Article | Year |
|---|---|
Adrenocortical cancer treatment.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Algorithms; Antineoplastic Combined Chemotherapy | 2009 |
1 trial available for mitotane and Syndrome
| Article | Year |
|---|---|
Adrenal steroid hormone concentrations in dogs with hair cycle arrest (Alopecia X) before and during treatment with melatonin and mitotane.
Topics: Administration, Oral; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Alopecia; Androstenedion | 2004 |
2 other studies available for mitotane and Syndrome
| Article | Year |
|---|---|
A six month mitotane course induced sustained correction of hypercortisolism in a young woman with PPNAD and Carney complex.
Topics: Adrenal Cortex Diseases; Adrenal Glands; Adult; Antineoplastic Agents, Hormonal; DNA; Female; Humans | 2005 |
Selected case reports in small animal dermatology.
Topics: Alopecia Areata; Animals; Calcinosis; Cat Diseases; Cats; Dermatitis; Dog Diseases; Dogs; Epinephrin | 1975 |