mitotane has been researched along with Remission, Spontaneous in 5 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
Remission, Spontaneous: A spontaneous diminution or abatement of a disease over time, without formal treatment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Measurement of o,p'-DDD and its metabolites in plasma may prove clinically useful in developing effective but less toxic dosage schedules." | 1.26 | o,p'-DDD (mitotane) therapy of adrenal cortical carcinoma: observations on drug dosage, toxicity, and steroid replacement. ( Borden, EC; Citrin, DL; Davis, TE; Hogan, TF; Johnson, BM; Nakamura, S, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Luton, JP | 1 |
| Mahoudeau, JA | 1 |
| Bouchard, P | 1 |
| Thieblot, P | 1 |
| Hautecouverture, M | 1 |
| Simon, D | 1 |
| Laudat, MH | 1 |
| Touitou, Y | 1 |
| Bricaire, H | 1 |
| Hogan, TF | 1 |
| Citrin, DL | 1 |
| Johnson, BM | 1 |
| Nakamura, S | 1 |
| Davis, TE | 1 |
| Borden, EC | 1 |
| Kirkegaard, C | 1 |
| Kolendorf, K | 1 |
| Lubitz, JA | 1 |
| Freeman, L | 1 |
| Okun, R | 1 |
| Komissarenko, VP | 1 |
5 other studies available for mitotane and Remission, Spontaneous
| Article | Year |
|---|---|
Treatment of Cushing's disease by O,p'DDD. Survey of 62 cases.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; | 1979 |
o,p'-DDD (mitotane) therapy of adrenal cortical carcinoma: observations on drug dosage, toxicity, and steroid replacement.
Topics: Adrenal Cortex Neoplasms; Adult; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Male; M | 1978 |
[Prolonged remission in Cushing's syndrome following treatment with ortho-para-dichlordiphenyldichlorethane].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Aldosterone; Cushing | 1974 |
Mitotane use in inoperable adrenal cortical carcinoma.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Diabetic Retinopathy; Female; Follow-Up Studies; Gastroi | 1973 |
[Letter to the editor].
Topics: Cushing Syndrome; Humans; Mitotane; Remission, Spontaneous | 1973 |