mitotane has been researched along with Primary Myelofibrosis in 1 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
Primary Myelofibrosis: A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bennett, BD | 1 |
| McKenna, TJ | 1 |
| Hough, AJ | 1 |
| Dean, R | 1 |
| Page, DL | 1 |
1 other study available for mitotane and Primary Myelofibrosis
| Article | Year |
|---|---|
Adrenal myelolipoma associated with Cushing's disease.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Gland Neoplasms; Cushing Syndrome; Humans; Male; Mito | 1980 |