mitotane has been researched along with Pregnancy in 14 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A 33-year-old woman who underwent surgery for adrenocortical carcinoma and treated with mitotane was referred for infertility." | 8.12 | Live birth after in-vitro maturation of oocytes in a patient with specific ovarian insufficiency caused by long-term mitotane treatment for adrenocortical carcinoma. ( Belin, F; Bry-Gauillard, H; Grynberg, M; Massin, N; Renoult-Pierre, P; Sifer, C; Vinolas, C; Young, J, 2022) |
| "We present the case of a female patient with virilising adrenocortical carcinoma treated surgically who conceived during adjuvant treatment with mitotane." | 7.77 | Pregnancy in a patient with adrenocortical carcinoma during treatment with Mitotane - a case report. ( Baszko-Błaszyk, D; Ochmańska, K; Sowiński, J; Waśko, R, 2011) |
| "Mitotane was stopped at gestation week 6." | 6.49 | Pregnancy in a patient with adrenal carcinoma treated with mitotane: a case report and review of literature. ( Blumenfeld, Z; Bronshtein, M; Jaffe, A; Salmon, A; Tripto-Shkolnik, L, 2013) |
| "The pregnancy was complicated by fetal exposure to mitotane and dexamethasone." | 5.37 | Normal adrenal function in an infant following a pregnancy complicated by maternal adrenal cortical carcinoma and mitotane exposure. ( Burym, C; Cronin, CM; Kojori, F; Salamon, E; Sellers, EA, 2011) |
| "Mitotane proved to be an efficacious drug which in exceptional cases can be used without significant side effects in low dosage for the long-term treatment of hypothalamic-pituitary Cushing disease." | 5.30 | [The long-term therapy of hypothalamic-hypophyseal Cushing's syndrome with mitotane (o,p'-DDD)]. ( Gerl, H; Knappe, G; Rohde, W; Ventz, M, 1997) |
| " A 33-year-old woman who underwent surgery for adrenocortical carcinoma and treated with mitotane was referred for infertility." | 4.12 | Live birth after in-vitro maturation of oocytes in a patient with specific ovarian insufficiency caused by long-term mitotane treatment for adrenocortical carcinoma. ( Belin, F; Bry-Gauillard, H; Grynberg, M; Massin, N; Renoult-Pierre, P; Sifer, C; Vinolas, C; Young, J, 2022) |
| "We present the case of a female patient with virilising adrenocortical carcinoma treated surgically who conceived during adjuvant treatment with mitotane." | 3.77 | Pregnancy in a patient with adrenocortical carcinoma during treatment with Mitotane - a case report. ( Baszko-Błaszyk, D; Ochmańska, K; Sowiński, J; Waśko, R, 2011) |
| "Although adrenocortical carcinoma (ACC) during pregnancy is rare, a retrospective review of a case series at our hospital revealed that almost one third of our patients were women in childbearing age." | 3.01 | Pregnancy in patients with adrenocortical carcinoma: a case-based discussion. ( Basile, V; Puglisi, S; Sperone, P; Terzolo, M, 2023) |
| "Mitotane was stopped at gestation week 6." | 2.49 | Pregnancy in a patient with adrenal carcinoma treated with mitotane: a case report and review of literature. ( Blumenfeld, Z; Bronshtein, M; Jaffe, A; Salmon, A; Tripto-Shkolnik, L, 2013) |
| "Virilizing adrenal carcinoma is a rare disease, especially in women of reproductive age." | 2.39 | Virilizing adrenal carcinoma in a woman of reproductive age: a case presentation and literature review. ( Coonrod, DV; Rizkallah, TH, 1995) |
| "The pregnancy was complicated by fetal exposure to mitotane and dexamethasone." | 1.37 | Normal adrenal function in an infant following a pregnancy complicated by maternal adrenal cortical carcinoma and mitotane exposure. ( Burym, C; Cronin, CM; Kojori, F; Salamon, E; Sellers, EA, 2011) |
| "Mitotane proved to be an efficacious drug which in exceptional cases can be used without significant side effects in low dosage for the long-term treatment of hypothalamic-pituitary Cushing disease." | 1.30 | [The long-term therapy of hypothalamic-hypophyseal Cushing's syndrome with mitotane (o,p'-DDD)]. ( Gerl, H; Knappe, G; Rohde, W; Ventz, M, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Bry-Gauillard, H | 1 |
| Belin, F | 1 |
| Vinolas, C | 1 |
| Renoult-Pierre, P | 1 |
| Massin, N | 1 |
| Young, J | 2 |
| Sifer, C | 1 |
| Grynberg, M | 1 |
| Puglisi, S | 3 |
| Basile, V | 3 |
| Sperone, P | 3 |
| Terzolo, M | 3 |
| Salle, L | 1 |
| Mas, R | 1 |
| Teissier-Clément, MP | 1 |
| Magkou, D | 1 |
| Do Cao, C | 1 |
| Bouvattier, C | 1 |
| Douillard, C | 1 |
| de Marcellus, C | 1 |
| Cazabat, L | 1 |
| Gérard, M | 1 |
| Raffin-Sanson, ML | 1 |
| Baszko-Błaszyk, D | 1 |
| Ochmańska, K | 1 |
| Waśko, R | 1 |
| Sowiński, J | 1 |
| Kojori, F | 1 |
| Cronin, CM | 1 |
| Salamon, E | 1 |
| Burym, C | 1 |
| Sellers, EA | 1 |
| Tripto-Shkolnik, L | 1 |
| Blumenfeld, Z | 1 |
| Bronshtein, M | 1 |
| Salmon, A | 1 |
| Jaffe, A | 1 |
| Wassermann, M | 1 |
| Bercovici, B | 1 |
| Cucos, S | 1 |
| Wassermann, D | 1 |
| Ron, M | 1 |
| Coonrod, DV | 1 |
| Rizkallah, TH | 1 |
| Knappe, G | 1 |
| Gerl, H | 1 |
| Ventz, M | 1 |
| Rohde, W | 1 |
| Foster, W | 1 |
| Chan, S | 1 |
| Platt, L | 1 |
| Hughes, C | 1 |
| Leiba, S | 1 |
| Weinstein, R | 1 |
| Shindel, B | 1 |
| Lapidot, M | 1 |
| Stern, E | 1 |
| Levavi, H | 1 |
| Rusecki, Y | 1 |
| Abramovici, A | 1 |
| Freeman, DA | 1 |
| Yamada, S | 1 |
4 reviews available for mitotane and Pregnancy
| Article | Year |
|---|---|
Pregnancy in patients with adrenocortical carcinoma: a case-based discussion.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Female; Humans; Male; Mitotane; Pregnancy; Retro | 2023 |
Pregnancy in patients with adrenocortical carcinoma: a case-based discussion.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Female; Humans; Male; Mitotane; Pregnancy; Retro | 2023 |
Pregnancy in patients with adrenocortical carcinoma: a case-based discussion.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Female; Humans; Male; Mitotane; Pregnancy; Retro | 2023 |
Pregnancy in patients with adrenocortical carcinoma: a case-based discussion.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Female; Humans; Male; Mitotane; Pregnancy; Retro | 2023 |
Pregnancy in patients with adrenocortical carcinoma: a case-based discussion.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Female; Humans; Male; Mitotane; Pregnancy; Retro | 2023 |
Pregnancy in patients with adrenocortical carcinoma: a case-based discussion.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Female; Humans; Male; Mitotane; Pregnancy; Retro | 2023 |
Pregnancy in patients with adrenocortical carcinoma: a case-based discussion.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Female; Humans; Male; Mitotane; Pregnancy; Retro | 2023 |
Pregnancy in patients with adrenocortical carcinoma: a case-based discussion.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Female; Humans; Male; Mitotane; Pregnancy; Retro | 2023 |
Pregnancy in patients with adrenocortical carcinoma: a case-based discussion.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Female; Humans; Male; Mitotane; Pregnancy; Retro | 2023 |
Pregnancy in a patient with adrenal carcinoma treated with mitotane: a case report and review of literature.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Antineoplastic Agents, Hormonal; Fatal Ou | 2013 |
Virilizing adrenal carcinoma in a woman of reproductive age: a case presentation and literature review.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Carcinoma; Female; Hirsutism; Humans; Infertility, F | 1995 |
Steroid hormone-producing tumors in man.
Topics: 17-Ketosteroids; Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Androgens; C | 1986 |
10 other studies available for mitotane and Pregnancy
| Article | Year |
|---|---|
Live birth after in-vitro maturation of oocytes in a patient with specific ovarian insufficiency caused by long-term mitotane treatment for adrenocortical carcinoma.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Female; Humans; In Vitro Oocyte Maturation Techn | 2022 |
Ectopic adrenocortical carcinoma of the ovary: An unexpected outcome.
Topics: ACTH Syndrome, Ectopic; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Antineoplastic Ag | 2020 |
Foetal exposure to mitotane/Op'DDD: Post-natal study of four children.
Topics: Adult; Child, Preschool; Dichlorodiphenyldichloroethane; Female; Fetus; Humans; Infant; Infant, Newb | 2018 |
Pregnancy in a patient with adrenocortical carcinoma during treatment with Mitotane - a case report.
Topics: Abortion, Induced; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Antineoplastic Agents, | 2011 |
Normal adrenal function in an infant following a pregnancy complicated by maternal adrenal cortical carcinoma and mitotane exposure.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Carcinoma; Antineoplastic Agents, Hormonal; | 2011 |
Storage of some organochlorine compounds in toxemia of pregnancy.
Topics: Adult; Chromatography; Chromatography, Gas; DDT; Dichlorodiphenyl Dichloroethylene; Female; Humans; | 1980 |
[The long-term therapy of hypothalamic-hypophyseal Cushing's syndrome with mitotane (o,p'-DDD)].
Topics: Adult; Chronic Disease; Combined Modality Therapy; Cushing Syndrome; Drug Evaluation; Female; Humans | 1997 |
Detection of endocrine disrupting chemicals in samples of second trimester human amniotic fluid.
Topics: Adult; Amniotic Fluid; Dichlorodiphenyl Dichloroethylene; Female; Gas Chromatography-Mass Spectromet | 2000 |
The protracted effect of o,p'-DDD in Cushing's disease and its impact on adrenal morphogenesis of young human embryo.
Topics: Abortion, Therapeutic; Adrenal Glands; Adult; Cushing Syndrome; Female; Fetus; Humans; Middle Aged; | 1989 |
[Urinary 6beta-hydroxycortisol. II. Urinary 6beta-hydroxycortisol in different diseases and after administration of drugs].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Carcinoma; Cushing Syndrome; F | 1973 |