mitotane has been researched along with Orphan Diseases in 4 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
Orphan Diseases: Rare diseases that have not been well studied.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adrenocortical carcinomas are rare in children and sometimes occur in patients with predisposing syndrome like Li-Fraumeni or Beckwith-Wiedemann syndromes." | 2.47 | [Management of adrenocortical carcinomas in children]. ( Aubert, S; Delebarre, M; Leblond, P, 2011) |
| "Widespread metastatic adrenocortical carcinoma was confirmed on biopsy." | 1.62 | A rare case of right shoulder pain. ( Bansari, A; Kattan, JN; Radhakrishnan, NS, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brönimann, S | 3 |
| Garstka, N | 3 |
| Remzi, M | 3 |
| Bansari, A | 1 |
| Radhakrishnan, NS | 1 |
| Kattan, JN | 1 |
| Sedhom, R | 1 |
| Hu, S | 1 |
| Ohri, A | 1 |
| Infantino, D | 1 |
| Lubitz, S | 1 |
| Leblond, P | 1 |
| Delebarre, M | 1 |
| Aubert, S | 1 |
2 reviews available for mitotane and Orphan Diseases
| Article | Year |
|---|---|
Treatment of adrenocortical carcinoma: oncological and endocrine outcomes.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Humans; Immunotherapy; Medical Oncology; Mitotan | 2023 |
Treatment of adrenocortical carcinoma: oncological and endocrine outcomes.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Humans; Immunotherapy; Medical Oncology; Mitotan | 2023 |
Treatment of adrenocortical carcinoma: oncological and endocrine outcomes.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Humans; Immunotherapy; Medical Oncology; Mitotan | 2023 |
Treatment of adrenocortical carcinoma: oncological and endocrine outcomes.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Humans; Immunotherapy; Medical Oncology; Mitotan | 2023 |
[Management of adrenocortical carcinomas in children].
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Antineoplastic Agents, Hormonal; Beckwith-Wiedem | 2011 |
2 other studies available for mitotane and Orphan Diseases
| Article | Year |
|---|---|
A rare case of right shoulder pain.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Antineoplastic Agents, Hormonal; Fatal Ou | 2021 |
Symptomatic Cushing's syndrome and hyperandrogenemia in a steroid cell ovarian neoplasm: a case report.
Topics: Aged; Antineoplastic Agents, Hormonal; Cushing Syndrome; Disease Progression; Fatal Outcome; Female; | 2016 |