mitotane has been researched along with Necrotizing Pyelonephritis in 1 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In untreated hyperadrenocorticism, clinical problems may result from metastasis of an adrenocortical carcinoma, growth of a pituitary tumor, or complications associated with sustained hypercortisolemia itself, such as hypertension, cardiovascular disease, thromboembolism, glucose intolerance, and increased susceptibility to infection." | 2.40 | Complications and concurrent disease associated with canine hyperadrenocorticism. ( Nichols, R, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nichols, R | 1 |
1 review available for mitotane and Necrotizing Pyelonephritis
| Article | Year |
|---|---|
Complications and concurrent disease associated with canine hyperadrenocorticism.
Topics: Adrenal Cortex Diseases; Adrenocortical Hyperfunction; Animals; Antineoplastic Agents; Diabetes Comp | 1997 |