mitotane has been researched along with Melanoma in 2 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adrenal Cancer is an infrequent and very aggressive tumor." | 2.48 | Giant adrenal carcinoma associated with renal vein and inferior vena cava thrombus. Case report and literature review. ( Fernández Arjona, M; Garrido Abad, P; Gómez de Vicente, JM; Herranz Fernández, LM; Jiménez Gálvez, M; Santos Arrontes, D; Suárez Fonseca, C, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Garrido Abad, P | 1 |
| Gómez de Vicente, JM | 1 |
| Herranz Fernández, LM | 1 |
| Jiménez Gálvez, M | 1 |
| Santos Arrontes, D | 1 |
| Suárez Fonseca, C | 1 |
| Fernández Arjona, M | 1 |
| Carey, RM | 1 |
| Orth, DN | 1 |
| Hartmann, WH | 1 |
1 review available for mitotane and Melanoma
| Article | Year |
|---|---|
Giant adrenal carcinoma associated with renal vein and inferior vena cava thrombus. Case report and literature review.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Aged; Antineoplastic Agents; Carcinoma; Contraindications; F | 2012 |
1 other study available for mitotane and Melanoma
| Article | Year |
|---|---|
Malignant melanoma with ectopic production of adrenocorticotropic hormone. Palliative treatment with inhibitors of adrenal steroid biosynthesis.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Adrenocorticotropic Hormon | 1973 |