mitotane has been researched along with Innate Inflammatory Response in 2 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment for advanced adrenocortical carcinoma (ACC) consists of mitotane alone or combined with etoposide, doxorubicin, and cisplatin (EDP)." | 4.31 | Inflammation-based scores as predictors of treatment response in advanced adrenocortical carcinoma. ( Abbas, H; Altieri, B; Asia, M; Detomas, M; Elhassan, YS; Mangone, A; Mantovani, G; Prete, A; Ronchi, CL, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Mangone, A | 1 |
| Altieri, B | 1 |
| Detomas, M | 1 |
| Prete, A | 1 |
| Abbas, H | 1 |
| Asia, M | 1 |
| Elhassan, YS | 1 |
| Mantovani, G | 1 |
| Ronchi, CL | 1 |
2 other studies available for mitotane and Innate Inflammatory Response
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Inflammation-based scores as predictors of treatment response in advanced adrenocortical carcinoma.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Female; Humans; Inflammation; Lymphocytes; Middl | 2023 |