mitotane has been researched along with Inflammation in 2 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment for advanced adrenocortical carcinoma (ACC) consists of mitotane alone or combined with etoposide, doxorubicin, and cisplatin (EDP)." | 4.31 | Inflammation-based scores as predictors of treatment response in advanced adrenocortical carcinoma. ( Abbas, H; Altieri, B; Asia, M; Detomas, M; Elhassan, YS; Mangone, A; Mantovani, G; Prete, A; Ronchi, CL, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Mangone, A | 1 |
| Altieri, B | 1 |
| Detomas, M | 1 |
| Prete, A | 1 |
| Abbas, H | 1 |
| Asia, M | 1 |
| Elhassan, YS | 1 |
| Mantovani, G | 1 |
| Ronchi, CL | 1 |
2 other studies available for mitotane and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Inflammation-based scores as predictors of treatment response in advanced adrenocortical carcinoma.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Female; Humans; Inflammation; Lymphocytes; Middl | 2023 |