mitotane has been researched along with Hypertriglyceridemia in 1 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
Hypertriglyceridemia: A condition of elevated levels of TRIGLYCERIDES in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We found that the distribution of the lipophilic chemotherapeutic agent o,p'-DDD (mitotane) among serum (lipo)proteins was altered in hypertriglyceridemia, with relatively more o,p'-DDD accumulating in the chylomicron and very-low-density lipoprotein (VLDL) fraction." | 7.68 | The distribution of o,p'-DDD (mitotane) among serum lipoproteins in normo- and hypertriglyceridemia. ( Gebhardt, DO; Gevers Leuven, JA; Moolenaar, AJ; van der Velde, EA; van Seters, AP, 1992) |
| "We found that the distribution of the lipophilic chemotherapeutic agent o,p'-DDD (mitotane) among serum (lipo)proteins was altered in hypertriglyceridemia, with relatively more o,p'-DDD accumulating in the chylomicron and very-low-density lipoprotein (VLDL) fraction." | 3.68 | The distribution of o,p'-DDD (mitotane) among serum lipoproteins in normo- and hypertriglyceridemia. ( Gebhardt, DO; Gevers Leuven, JA; Moolenaar, AJ; van der Velde, EA; van Seters, AP, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gebhardt, DO | 1 |
| Moolenaar, AJ | 1 |
| van Seters, AP | 1 |
| van der Velde, EA | 1 |
| Gevers Leuven, JA | 1 |
1 other study available for mitotane and Hypertriglyceridemia
| Article | Year |
|---|---|
The distribution of o,p'-DDD (mitotane) among serum lipoproteins in normo- and hypertriglyceridemia.
Topics: Adrenal Cortex Neoplasms; Carcinoma; Chromatography, Gas; Chylomicrons; Humans; Hypertriglyceridemia | 1992 |