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mitotane and Hypertriglyceridemia

mitotane has been researched along with Hypertriglyceridemia in 1 studies

Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.

Hypertriglyceridemia: A condition of elevated levels of TRIGLYCERIDES in the blood.

Research Excerpts

ExcerptRelevanceReference
"We found that the distribution of the lipophilic chemotherapeutic agent o,p'-DDD (mitotane) among serum (lipo)proteins was altered in hypertriglyceridemia, with relatively more o,p'-DDD accumulating in the chylomicron and very-low-density lipoprotein (VLDL) fraction."7.68The distribution of o,p'-DDD (mitotane) among serum lipoproteins in normo- and hypertriglyceridemia. ( Gebhardt, DO; Gevers Leuven, JA; Moolenaar, AJ; van der Velde, EA; van Seters, AP, 1992)
"We found that the distribution of the lipophilic chemotherapeutic agent o,p'-DDD (mitotane) among serum (lipo)proteins was altered in hypertriglyceridemia, with relatively more o,p'-DDD accumulating in the chylomicron and very-low-density lipoprotein (VLDL) fraction."3.68The distribution of o,p'-DDD (mitotane) among serum lipoproteins in normo- and hypertriglyceridemia. ( Gebhardt, DO; Gevers Leuven, JA; Moolenaar, AJ; van der Velde, EA; van Seters, AP, 1992)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gebhardt, DO1
Moolenaar, AJ1
van Seters, AP1
van der Velde, EA1
Gevers Leuven, JA1

Other Studies

1 other study available for mitotane and Hypertriglyceridemia

ArticleYear
The distribution of o,p'-DDD (mitotane) among serum lipoproteins in normo- and hypertriglyceridemia.
    Cancer chemotherapy and pharmacology, 1992, Volume: 29, Issue:4

    Topics: Adrenal Cortex Neoplasms; Carcinoma; Chromatography, Gas; Chylomicrons; Humans; Hypertriglyceridemia

1992