Page last updated: 2024-10-31

mitotane and Hyperplasia

mitotane has been researched along with Hyperplasia in 7 studies

Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research Excerpts

ExcerptRelevanceReference
"We report a case of adrenocorticotropic hormone (ACTH)-independent bilateral macronodular adrenocortical hyperplasia (AIMAH), which was successfully treated with mitotane."7.70Adrenocorticotropic hormone-independent bilateral adrenocortical macronodular hyperplasia treated with mitotane. ( Arakawa, M; Komura, S; Nagai, M; Narita, I; Omori, K, 1999)
"We report a case of adrenocorticotropic hormone (ACTH)-independent bilateral macronodular adrenocortical hyperplasia (AIMAH), which was successfully treated with mitotane."3.70Adrenocorticotropic hormone-independent bilateral adrenocortical macronodular hyperplasia treated with mitotane. ( Arakawa, M; Komura, S; Nagai, M; Narita, I; Omori, K, 1999)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nagai, M1
Narita, I1
Omori, K1
Komura, S1
Arakawa, M1
Besser, GM1
Jeffcoate, WJ1
Owens, JM1
Drucker, WD1
Kelly, DF1
Darke, PG1
Butez, J1
Bonnin, A1
Luton, JP2
Pallardy, G1
Ledoux-Lebard, G1
Bricaire, H1
Touitou, Y1
Moolenaar, AJ1
Bogdan, A1
Auzéby, A1
Sizonenko, PC1
Doret, AM1
Riondel, AM1
Paunier, L1

Reviews

2 reviews available for mitotane and Hyperplasia

ArticleYear
Hyperadrenocorticism in the dog: canine Cushing's syndrome.
    The Veterinary clinics of North America, 1977, Volume: 7, Issue:3

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Cortex Function Tests; Adrenal Gland Neoplasms; Adrenal

1977
Cushing's syndrome in the dog.
    The Veterinary record, 1976, Jan-10, Volume: 98, Issue:2

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Animals; Calcinosis; Cu

1976

Other Studies

5 other studies available for mitotane and Hyperplasia

ArticleYear
Adrenocorticotropic hormone-independent bilateral adrenocortical macronodular hyperplasia treated with mitotane.
    Internal medicine (Tokyo, Japan), 1999, Volume: 38, Issue:12

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aged; Humans; Hyperplasia; Male; Mitotane; Neoplasms, M

1999
Endocrine and metabolic diseases. Adrenal diseases.
    British medical journal, 1976, Feb-21, Volume: 1, Issue:6007

    Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Insuffici

1976
[Value of retropneumoperitoneum in the exploration of Cushing's syndrome. 155 cases].
    La Nouvelle presse medicale, 1975, Mar-29, Volume: 4, Issue:13

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Hyperfunction; Angiography; Cushing

1975
o,p'-DDD (mitotane) treatment for Cushing's syndrome: adrenal drug concentration and inhibition in vitro of steroid synthesis.
    European journal of clinical pharmacology, 1985, Volume: 29, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Carcinoma; Child; Cort

1985
Cushing's syndrome due to bilateral adrenal cortical hyperplasia in a 13-year old girl: successful treatment with op'DDD'.
    Helvetica paediatrica acta, 1974, Volume: 29, Issue:3

    Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Diseases; Body Height; Body Weig

1974