mitotane has been researched along with Hyperplasia in 7 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of adrenocorticotropic hormone (ACTH)-independent bilateral macronodular adrenocortical hyperplasia (AIMAH), which was successfully treated with mitotane." | 7.70 | Adrenocorticotropic hormone-independent bilateral adrenocortical macronodular hyperplasia treated with mitotane. ( Arakawa, M; Komura, S; Nagai, M; Narita, I; Omori, K, 1999) |
| "We report a case of adrenocorticotropic hormone (ACTH)-independent bilateral macronodular adrenocortical hyperplasia (AIMAH), which was successfully treated with mitotane." | 3.70 | Adrenocorticotropic hormone-independent bilateral adrenocortical macronodular hyperplasia treated with mitotane. ( Arakawa, M; Komura, S; Nagai, M; Narita, I; Omori, K, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nagai, M | 1 |
| Narita, I | 1 |
| Omori, K | 1 |
| Komura, S | 1 |
| Arakawa, M | 1 |
| Besser, GM | 1 |
| Jeffcoate, WJ | 1 |
| Owens, JM | 1 |
| Drucker, WD | 1 |
| Kelly, DF | 1 |
| Darke, PG | 1 |
| Butez, J | 1 |
| Bonnin, A | 1 |
| Luton, JP | 2 |
| Pallardy, G | 1 |
| Ledoux-Lebard, G | 1 |
| Bricaire, H | 1 |
| Touitou, Y | 1 |
| Moolenaar, AJ | 1 |
| Bogdan, A | 1 |
| Auzéby, A | 1 |
| Sizonenko, PC | 1 |
| Doret, AM | 1 |
| Riondel, AM | 1 |
| Paunier, L | 1 |
2 reviews available for mitotane and Hyperplasia
| Article | Year |
|---|---|
Hyperadrenocorticism in the dog: canine Cushing's syndrome.
Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Cortex Function Tests; Adrenal Gland Neoplasms; Adrenal | 1977 |
Cushing's syndrome in the dog.
Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Animals; Calcinosis; Cu | 1976 |
5 other studies available for mitotane and Hyperplasia
| Article | Year |
|---|---|
Adrenocorticotropic hormone-independent bilateral adrenocortical macronodular hyperplasia treated with mitotane.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aged; Humans; Hyperplasia; Male; Mitotane; Neoplasms, M | 1999 |
Endocrine and metabolic diseases. Adrenal diseases.
Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Insuffici | 1976 |
[Value of retropneumoperitoneum in the exploration of Cushing's syndrome. 155 cases].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Hyperfunction; Angiography; Cushing | 1975 |
o,p'-DDD (mitotane) treatment for Cushing's syndrome: adrenal drug concentration and inhibition in vitro of steroid synthesis.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Carcinoma; Child; Cort | 1985 |
Cushing's syndrome due to bilateral adrenal cortical hyperplasia in a 13-year old girl: successful treatment with op'DDD'.
Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Diseases; Body Height; Body Weig | 1974 |