mitotane has been researched along with Hypercholesterolemia in 4 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
Hypercholesterolemia: A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We herein report a case of marked transient hypercholesterolemia in a man receiving low-dose mitotane as adjuvant chemotherapy for adrenocortical carcinoma." | 7.80 | Marked transient hypercholesterolemia caused by low-dose mitotane as adjuvant chemotherapy for adrenocortical carcinoma. ( Inazu, A; Kawashiri, MA; Mabuchi, H; Nohara, A; Tada, H; Yamagishi, M, 2014) |
| "We herein report a case of marked transient hypercholesterolemia in a man receiving low-dose mitotane as adjuvant chemotherapy for adrenocortical carcinoma." | 3.80 | Marked transient hypercholesterolemia caused by low-dose mitotane as adjuvant chemotherapy for adrenocortical carcinoma. ( Inazu, A; Kawashiri, MA; Mabuchi, H; Nohara, A; Tada, H; Yamagishi, M, 2014) |
| "Ortho,para,dichlorodiphenyl dichloroethane (o,p'DDD, Mitotane (Roussell)) is used as an adrenolytic drug to reduce adrenocortical mass and circulating cortisol levels in Cushing's syndrome but has the unwanted side-effect of inducing hypercholesterolaemia." | 3.68 | Possible mechanism and treatment of o,p'DDD-induced hypercholesterolaemia. ( Anderson, JV; Besser, GM; Maher, VM; Scoppola, A; Thompson, GR; Trainer, PJ, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tada, H | 1 |
| Nohara, A | 1 |
| Kawashiri, MA | 1 |
| Inazu, A | 1 |
| Mabuchi, H | 1 |
| Yamagishi, M | 1 |
| Trainer, PJ | 2 |
| Besser, M | 1 |
| Maher, VM | 1 |
| Scoppola, A | 1 |
| Anderson, JV | 1 |
| Thompson, GR | 1 |
| Besser, GM | 1 |
| Vassilopoulou-Sellin, R | 1 |
| Samaan, NA | 1 |
4 other studies available for mitotane and Hypercholesterolemia
| Article | Year |
|---|---|
Marked transient hypercholesterolemia caused by low-dose mitotane as adjuvant chemotherapy for adrenocortical carcinoma.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Antineoplastic Agents; Chemotherapy, Adjuvant; C | 2014 |
Cushing's disease.
Topics: Antineoplastic Agents, Hormonal; Cushing Syndrome; Humans; Hypercholesterolemia; Mitotane | 2000 |
Possible mechanism and treatment of o,p'DDD-induced hypercholesterolaemia.
Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cushing Syndrome; Cytochrome P-450 Enzyme System | 1992 |
Mitotane administration: an unusual cause of hypercholesterolemia.
Topics: Adrenal Gland Neoplasms; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Mitotane | 1991 |