mitotane has been researched along with Hormone-Dependent Neoplasms in 2 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berruti, A | 1 |
| Baudin, E | 1 |
| Gelderblom, H | 1 |
| Haak, HR | 1 |
| Porpiglia, F | 1 |
| Fassnacht, M | 1 |
| Pentheroudakis, G | 1 |
| Kvacheniuk, AM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Mitotane With or Without Cisplatin and Etoposide After Surgery in Treating Participants With Stage I-III Adrenocortical Cancer With High Risk of Recurrence[NCT03723941] | Phase 3 | 240 participants (Anticipated) | Interventional | 2018-07-01 | Recruiting | ||
| Activity of Abiraterone Acetate in the Management of Cushing's Syndrome in Patients With Adrenocortical Carcinoma[NCT03145285] | Phase 2 | 10 participants (Anticipated) | Interventional | 2017-04-18 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for mitotane and Hormone-Dependent Neoplasms
| Article | Year |
|---|---|
Adrenal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Antineoplastic Agents, Hormonal; A | 2012 |
Adrenal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Antineoplastic Agents, Hormonal; A | 2012 |
Adrenal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Antineoplastic Agents, Hormonal; A | 2012 |
Adrenal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Antineoplastic Agents, Hormonal; A | 2012 |
[Features of clinical presentation of malignant adrenocortical tumor cortex metabolism over time].
Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Antineoplastic Agents, Hormon | 2003 |