mitotane has been researched along with Genetic Predisposition in 3 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adrenocortical carcinomas are rare in children and sometimes occur in patients with predisposing syndrome like Li-Fraumeni or Beckwith-Wiedemann syndromes." | 2.47 | [Management of adrenocortical carcinomas in children]. ( Aubert, S; Delebarre, M; Leblond, P, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Patalano, A | 1 |
| Brancato, V | 1 |
| Mantero, F | 1 |
| Wandoloski, M | 1 |
| Bussey, KJ | 1 |
| Demeure, MJ | 1 |
| Leblond, P | 1 |
| Delebarre, M | 1 |
| Aubert, S | 1 |
3 reviews available for mitotane and Genetic Predisposition
| Article | Year |
|---|---|
Adrenocortical cancer treatment.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Algorithms; Antineoplastic Combined Chemotherapy | 2009 |
Adrenocortical cancer.
Topics: Adrenal Cortex Neoplasms; Antineoplastic Agents, Hormonal; Combined Modality Therapy; Diagnosis, Dif | 2009 |
[Management of adrenocortical carcinomas in children].
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Antineoplastic Agents, Hormonal; Beckwith-Wiedem | 2011 |